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CCR4-NOT Transcription Complex, Subunit 3 Proteins (CNOT3)

The CCR4-NOT complex functions as general transcription regulation complex.. Additionally we are shipping CNOT3 Antibodies (61) and CNOT3 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNOT3 4849 O75175
CNOT3 232791 Q8K0V4
Rat CNOT3 CNOT3 308311  
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Top CNOT3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CNOT3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for CCR4-NOT Transcription Complex, Subunit 3 (CNOT3) Interaction Partners

Human CCR4-NOT Transcription Complex, Subunit 3 (CNOT3) interaction partners

  1. A mutation in PRPF31 (show PRPF31 Proteins) is hypostatic to a trait acting on CNOT3, with the RP11 (show PRPF31 Proteins) phenotype only being observed when there is homozygous (recessive) inheritance of the higher expressivity CNOT3 ("symptomatic" or risk) allele.

  2. The CNOT2-CNOT3 heterodimer is stabilized and tightly anchored to the surface of CNOT1 through an unexpected intertwined arrangement of peptide regions lacking defined secondary structure.

  3. In asymptomatic carriers CNOT3 is expressed at low levels, allowing higher amounts of wild-type PRPF31 (show PRPF31 Proteins) transcripts to be produced and preventing manifestation of retinal degeneration.

  4. CNOT3 is a tumor suppressor mutated in 7 of 89 (7.9%) adult T-cell acute lymphoblastic leukemias, and its knockdown causes tumors in a sensitized Drosophila melanogaster model.

  5. Cnot1, Cnot2 (show CNOT2 Proteins), and Cnot3 represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs (show NR2E3 Proteins).

  6. A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis.

  7. CNOT3 depletion stabilizes the MAD1 (show MXD1 Proteins) mRNA, and MAD1 (show MXD1 Proteins) knockdown attenuates the CNOT3 depletion-induced increase of the mitotic index.

  8. TBP-interacting protein 120B (show CAND2 Proteins) binds to NOT3

Mouse (Murine) CCR4-NOT Transcription Complex, Subunit 3 (CNOT3) interaction partners

  1. CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins, Ripk1 (show RIPK1 Proteins) and Ripk3 (show RIPK3 Proteins).

  2. data suggest that the CCR4 (show CCR4 Proteins)-NOT complex regulates B cell differentiation by controlling Igh rearrangement and destabilizing p53 (show TP53 Proteins) mRNA.

  3. These data have uncovered a novel role of core components of the Ccr4 (show CCR4 Proteins)-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  4. CNOT3 is a critical regulator of bone mass acting on bone resorption through posttranscriptional down-regulation of RANK mRNA stability, at least in part, even in aging-induced osteoporosis.

  5. Cnot1, Cnot2 (show CNOT2 Proteins), and Cnot3 represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs (show NR2E3 Proteins).

  6. CNOT3 responds to feeding conditions to regulate deadenylation-specific mRNAs and energy metabolism

CNOT3 Protein Profile

Protein Summary

The CCR4-NOT complex functions as general transcription regulation complex.

Gene names and symbols associated with CNOT3

  • CCR4-NOT transcription complex, subunit 3b (cnot3b)
  • CCR4-NOT transcription complex, subunit 3 (CNOT3)
  • CCR4-NOT transcription complex, subunit 3 (AFUA_2G02070)
  • CCR4-NOT transcription complex, subunit 3 (NFIA_034440)
  • CCR4-NOT transcription complex, subunit 3 (ACLA_092760)
  • CCR4-NOT transcription complex, subunit 3 (PMAA_089540)
  • CCR4-NOT transcription complex, subunit 3 (AFLA_043060)
  • CCR4-NOT transcription complex, subunit 3 (TSTA_125290)
  • CCR4-NOT transcription complex, subunit 3 (ANI_1_738064)
  • CCR4-NOT transcription complex, subunit 3 (AOR_1_812054)
  • lethal (2) NC136 (l(2)NC136)
  • CCR4-NOT transcription complex, subunit 3 (cnot3)
  • CCR4-NOT transcription complex, subunit 3 (Cnot3)
  • CCR4-NOT transcription complex, subunit 3a (cnot3a)
  • A930039N10Rik protein
  • Afu2g02070 protein
  • AO090011000479 protein
  • CG8426 protein
  • CNOT3 protein
  • Dmel\\CG8426 protein
  • fb73b06 protein
  • fc17h07 protein
  • LENG2 protein
  • not3 protein
  • NOT3.5 protein
  • not3/5 protein
  • NOT3H protein
  • wu:fb73b06 protein
  • wu:fc17h07 protein
  • wu:fi20g07 protein
  • zgc:55934 protein
  • zgc:92813 protein

Protein level used designations for CNOT3

CCR4-NOT transcription complex, subunit 3 , CG8426-PA , CG8426-PB , l(2)NC136-PA , l(2)NC136-PB , lethal(2)NC136 , CCR4-NOT transcription complex subunit 3-like , CCR4-NOT transcription complex subunit 3 , CCR4-associated factor 3 , NOT3 (negative regulator of transcription 3, yeast) homolog , leukocyte receptor cluster member 2

GENE ID SPECIES
327627 Danio rerio
456279 Pan troglodytes
3507170 Aspergillus fumigatus Af293
4593054 Neosartorya fischeri NRRL 181
4705265 Aspergillus clavatus NRRL 1
7026081 Talaromyces marneffei ATCC 18224
7913080 Aspergillus flavus NRRL3357
8100308 Talaromyces stipitatus ATCC 10500
100137337 Papio anubis
4981861 Aspergillus niger CBS 513.88
5998212 Aspergillus oryzae RIB40
35501 Drosophila melanogaster
693292 Macaca mulatta
100464278 Ailuropoda melanoleuca
100520963 Sus scrofa
100564141 Anolis carolinensis
4849 Homo sapiens
484312 Canis lupus familiaris
527305 Bos taurus
100328776 Oryctolagus cuniculus
232791 Mus musculus
308311 Rattus norvegicus
449540 Danio rerio
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