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CD109 Molecule Proteins (CD109)

CD109 encodes a member of the alpha2-macroglobulin/complement superfamily. Additionally we are shipping CD109 Antibodies (74) and CD109 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD109 235505 Q8R422
CD109 135228 Q6YHK3
CD109 363104  
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Top CD109 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details

CD109 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human
,
Rat (Rattus)

More Proteins for CD109 Molecule (CD109) Interaction Partners

Mouse (Murine) CD109 Molecule (CD109) interaction partners

  1. GP96 (show HSP90B1 Proteins) serves as an essential chaperone for the cell-surface protein (show CD28 Proteins) glycoprotein A repetitions predominant (GARP (show LRRC32 Proteins)), which is a docking receptor for latent membrane-associated TGF-beta (show TGFB1 Proteins) (mLTGF-beta).

  2. CD109 decreases extracellular matrix production and fibrotic responses during hypoxic wound healing

  3. CD109 is present in serum as a soluble form, and suggest its potential as a novel tumor marker in patients with cancers that express CD109.

  4. CD109 might be an important regulator of osteoclastogenesis.

  5. findings demonstrate that CD109 overexpression in the epidermis reduces inflammation and granulation tissue area and improves collagen organization in vivo.

  6. Induction of both Th17-producing cells and Tregs is caused preferentially by Tregs expressing the latent TGF-beta1 (show TGFB1 Proteins)/GARP (show LRRC32 Proteins) complex on their cell surface rather than by secreted latent TGF-beta1 (show TGFB1 Proteins).

  7. CD109 overexpression ameliorates skin fibrosis in a mouse model of bleomycin-induced scleroderma.

  8. CD109 regulates differentiation of keratinocytes via a signaling pathway involving Stat3 (show STAT3 Proteins).

Human CD109 Molecule (CD109) interaction partners

  1. sCD109 can bind TGF-beta (show TGFB1 Proteins), inhibit TGF-beta (show TGFB1 Proteins) binding to its receptors and decrease TGF-beta (show TGFB1 Proteins) signalling and TGF-beta (show TGFB1 Proteins)-induced cellular responses.

  2. These findings indicate that CD109 is an exosomal protein and that the C-terminal region of CD109 is required for its presence in the exosome.

  3. CD109 may be a potential pathology marker for gallbladder squamous cell/adenosquamous carcinomas.

  4. CD109 is specifically expressed in endothelial cells of cutaneous cavernous haemangioma.

  5. The results suggest that circulating endothelial cells express CD109 and represent a rare population of circulating tumor endothelial cells, that play a potentially useful prognostic role in patients with glioblastoma.

  6. CD109 overexpression was significantly associated with surgical stage, distant metastasis, and poor prognosis in myxofibrosarcoma.

  7. Three glioblastoma cell lines, SK-MG-1, U251MG and MG178, were tested and CD109 overexpression attenuated TGF-beta1 (show TGFB1 Proteins) signaling and enhanced EGF (show EGF Proteins) signaling in SK-MG-1, but not in U251MG or MG178.

  8. CD109 is highly expressed in TNBC and is a potential biomarker for the initiation, progression, and differentiation of breast cancer tumors.

  9. CD109 plays a critical role in non-small-cell lung cancer (NSCLC) progression, and is overexpressed in advanced NSCLC

  10. High expression of CD109 antigen regulates the phenotype of cancer stem-like cells/cancer-initiating cells in a novel epithelioid sarcoma cell line ESX (show ELF3 Proteins) and is related to poor prognosis of soft tissue sarcoma.

CD109 Protein Profile

Protein Summary

This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD109 Molecule Proteins (CD109)

  • CD109 molecule (CD109)
  • CD109 molecule (cd109)
  • CD109 antigen (Cd109)
  • CD109 molecule (Cd109)
  • 9930012E15Rik protein
  • AI480638 protein
  • CD109 protein
  • CPAMD7 protein
  • GARP protein
  • RP11-525G3.1 protein

Protein level used designations for CD109 Molecule Proteins (CD109)

CD109 molecule , CD109 antigen-like , GPI-anchored alpha 2 macroglobulin-related protein , GPI-anchored alpha-2 macroglobulin-related protein , Gov platelet alloantigens , 150 kDa TGF-beta-1-binding protein , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7 , CD109 antigen , activated T-cell marker CD109 , p180 , platelet-specific Gov antigen , r150

GENE ID SPECIES
100068163 Equus caballus
421862 Gallus gallus
462825 Pan troglodytes
569058 Danio rerio
100385557 Callithrix jacchus
100471342 Ailuropoda melanoleuca
100486953 Xenopus (Silurana) tropicalis
235505 Mus musculus
135228 Homo sapiens
474970 Canis lupus familiaris
100155478 Sus scrofa
534043 Bos taurus
363104 Rattus norvegicus
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