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CD1c Molecule Proteins (CD1C)

CD1C encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping CD1c Antibodies (142) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD1C 911 P29017
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Top CD1c Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CD1C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for CD1c Molecule (CD1C) Interaction Partners

Human CD1c Molecule (CD1C) interaction partners

  1. human CD1c adopts different conformations dependent on ligand occupancy of its groove, with CE and ASG (show ARSG Proteins) stabilizing CD1c conformations that provide a footprint for binding of CD1c self-reactive T-cell receptors

  2. There was a significant increase of blood CD1c(+) myeloid dendritic cells in autoimmune uveitis patients. The mature phenotype and function of CD1c(+) mDC1 were regulated by TNFalpha (show TNF Proteins) via a p38 MAPK (show MAPK14 Proteins)-dependent pathway.

  3. decidual CD1c(+) dendritic cells with Toxoplasma gondii infection have enhanced cytotoxicity of decidual natural killer cells

  4. hMPV-infected BDCA-1(+) and BDCA-3 (show THBD Proteins)(+) mDCs induced expansion of Th17 cells, in response to RSV, BDCA-1(+) mDCs induced expansion of Th1 (show TH1L Proteins) cells and BDCA-3 (show THBD Proteins)(+) mDCs induced expansion of Th2 cells and Tregs

  5. mLPA-specific T cells efficiently kill CD1c(+) acute leukemia cells, poorly recognize nontransformed CD1c-expressing cells, and protect immunodeficient mice against CD1c(+) human leukemia cells.

  6. [review] Humans express both Group 1 (CD1a, CD1b and CD1c) and Group 2 (CD1d) CD1 molecules with nonredundant functions in response to the presentation of endogenous lipids.

  7. Activated dendritic cell subsets expressing CD141 (show THBD Proteins)/CLEA9A/CD1c, likely recruited into the tubulointerstitium, are positioned to play a role in the development of fibrosis and, thus, progression to chronic kidney disease.

  8. CD1c+ myeloid dendritic cells were increased in idiopathic pulmonary fibrosis patients versus controls.

  9. RSV infection induces a distinct pattern of costimulatory molecule (show CD276 Proteins) expression and cytokine production by BDCA-1(+) and BDCA-3 (show THBD Proteins)(+) mDCs, and impairs their ability to stimulate T cell proliferation.

  10. for isoforms CD1b (show CD1B Proteins) through CD1e (show CD1e Proteins), our simulations show the near-complete collapse of the hydrophobic cavities in the absence of the antigen. This event results from the spontaneous closure of the binding domain entrance, flanked by two alpha-helices.

Rhesus Monkey CD1c Molecule (CD1C) interaction partners

  1. GMM-specific, CD1c-restricted T cells were detected in the circulation of all 4 rhesus macaque monkeys tested after but not before vaccination with BCG (show SLC11A1 Proteins).

  2. Data show that the CD1c+ cells were found to be mononuclear leukocytes rather than granulocytes, and most of them expressed CD20 (show MS4A1 Proteins).

CD1c (CD1C) Protein Profile

Protein Summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Gene names and symbols associated with CD1c Molecule Proteins (CD1C)

  • CD1c molecule (CD1C)
  • BDCA1 protein
  • CD1 protein
  • CD1A protein
  • R7 protein

Protein level used designations for CD1c Molecule Proteins (CD1C)

CD1C antigen, c polypeptide , T-cell surface glycoprotein CD1c , cortical thymocyte antigen CD1C , differentiation antigen CD1-alpha-3

GENE ID SPECIES
911 Homo sapiens
717148 Macaca mulatta
101116198 Ovis aries
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