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CD2 Molecule Proteins (CD2)

CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). Additionally we are shipping CD2 Antibodies (849) and CD2 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD2 12481 P08920
CD2 914 P06729
CD2 497761 P08921
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Top CD2 Proteins at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$272.80
Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 11 Days
$385.00
Details
HOST_Human Cells Cynomolgus Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Dog Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details

CD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
,
Human , , , , , ,
, , ,
Rat (Rattus) , ,
,

Top referenced CD2 Proteins

  1. Human CD2 Protein expressed in Human Cells - ABIN2003689 : Moingeon, Chang, Sayre, Clayton, Alcover, Gardner, Reinherz: The structural biology of CD2. in Immunological reviews 1990 (PubMed)
    Show all 2 references for ABIN2003689

  2. Human CD2 Protein expressed in Escherichia coli (E. coli) - ABIN1098728 : Yang, Ye, Carroll, Yang, Lee: Structural biology of the cell adhesion protein CD2: alternatively folded states and structure-function relation. in Current protein & peptide science 2002 (PubMed)
    Show all 2 references for ABIN1098728

  3. Mouse (Murine) CD2 Protein expressed in Human Cells - ABIN2007943 : McNerney, Kumar: The CD2 family of natural killer cell receptors. in Current topics in microbiology and immunology 2005 (PubMed)
    Show all 2 references for ABIN2007943

  4. Human CD2 Protein expressed in HEK-293 Cells - ABIN2180720 : Bodian, Jones, Harlos, Stuart, Davis: Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution. in Structure (London, England : 1993) 1995 (PubMed)
    Show all 2 references for ABIN2180720

More Proteins for CD2 Molecule (CD2) Interaction Partners

Mouse (Murine) CD2 Molecule (CD2) interaction partners

  1. Ptpn22 (show PTPN22 Proteins) and Cd2 (show CCND2 Proteins) Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes

  2. CD2 (show CCND2 Proteins) stimuli were mandatory for Treg cell survival with reduced Bim (show BCL2L11 Proteins) expression, but CD2 (show CCND2 Proteins) may not function as a direct receptor for molecules on stromal cells.

  3. CD2 (show CCND2 Proteins) is important for the efficient development of CD4 (show CD4 Proteins) single-positive thymocytes and TCR-dependent activation of mature CD4 (show CD4 Proteins) lymph node T cells, but does not direct a particular helper T cell subset polarity.

  4. molecular mechanism of heterophilic adhesion between the murine T-cell adhesion glycoprotein (show CD226 Proteins) CD2 (show CCND2 Proteins) and its ligand CD48 (show CD48 Proteins)

  5. Despite normal T cell numbers, mice deficient in the costimulatory molecules CD2 (show CCND2 Proteins) and CD28 (show CD28 Proteins) spontaneously develop Pneumocystis carinii pneumonia.

  6. autoimmunity may be mediated by a combination of genes in the SLAM (show SLAMF1 Proteins)/CD2 (show CCND2 Proteins) family cluster

  7. Analysis of the ligand-receptor pairs involved in induction of germline transcripts (Igamma2a) necessary for switch recombination revealed that expression of CD48 (show CD48 Proteins) on B cells and ligands CD2 (show CCND2 Proteins) and CD244 (show CD244 Proteins) on NK cells are able to stimulate Igamma2a

  8. CD2 (show CCND2 Proteins) deficient mice are more resistant to T. gondii infection than wild type mice

  9. nanoscale increases in CD2 (show CCND2 Proteins)-CD48 (show CD48 Proteins)-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse

  10. CD244 (show CD244 Proteins) inhibition and activation depends on CD2 (show CCND2 Proteins) and phospholipase C (show PLC Proteins)-gamma1

Human CD2 Molecule (CD2) interaction partners

  1. the fundamental mechanism of glycosylation of human CD2 is to promote CD2-CD58 (show CD58 Proteins) binding by conformational adjustment of CD2

  2. CD58 (show CD58 Proteins)/CD2 is the primary costimulatory pathway in human CD28 (show CD28 Proteins)-CD8 (show CD8A Proteins)+ T cells.

  3. Both the mRNA expression levels and protein expression levels of HSP27 (show HSPB1 Proteins) were increased in astrocytes from POAG patients compared with those from normal control, suggesting that mutation in CD2 might pose a risk for POAG in Chinese population.

  4. Although sMCs displayed immunoreactivity for one of the neoplastic antigens in the majority of SM patients, the aberrant CD2 and/or CD25 (show IL2RA Proteins) expression on sMCs is not as indicative of SM as the BMMC immunophenotype.

  5. ERGdel may be a pure surrogate of CD2-positivity--which has been suggested to be a good prognositc marker in childhood ALL

  6. Altogether, these results show that a high CD2 expression level is a hallmark of latently infected resting memory CD4 (show CD4 Proteins)(+) T cells in vivo.

  7. Aberrant CD2 expression appears to further determine a shorter progression free survival

  8. CD2-CD58 (show CD58 Proteins)/48 receptor-ligand interaction promotes and is required for nanotube formation in human natural killer cells.

  9. CD2 expression does not contribute to improve the diagnosis of systemic mastocytosis when compared with aberrant CD25 (show IL2RA Proteins) expression alone.

  10. CD2-mediated priming of resting natural killer (NK) cells is unaffected by their degree of functional maturation.

Pig (Porcine) CD2 Molecule (CD2) interaction partners

  1. CD2- gammadelta T cells showed CD2 de novo expression after ConA/IL-2 (show IL2 Proteins)/IL-12 (show IL12A Proteins)/IL-18 (show IL18 Proteins) stimulation.

  2. Porcine gamma-delta T lymphocytes can be categorized into two functionally and developmentally distinct subsets according to expression of CD2 and level of TCR.

CD2 Protein Profile

Protein Summary

CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986

Gene names and symbols associated with CD2 Molecule Proteins (CD2)

  • CD2 molecule (CD2)
  • CD2 antigen (Cd2)
  • Cd2 molecule (Cd2)
  • CD2 protein
  • CD2R protein
  • LFA-2 protein
  • LFA2 protein
  • Ly-37 protein
  • Ly37 protein
  • OX-34 protein
  • OX34 protein
  • SRBC protein
  • T11 protein

Protein level used designations for CD2 Molecule Proteins (CD2)

CD2 antigen (p50), sheep red blood cell receptor , T-cell surface antigen CD2 , cluster of differentiation 2 , CD2 antigen , CD2 molecule , LFA-3 receptor , T-cell surface antigen T11/Leu-5 , lymphocyte antigen 37 , erythrocyte receptor , lymphocyte-function antigen-2 , rosette receptor , OX-34 antigen , OX-45 surface antigen homolog to human T lymphocyte CD2 antigen , T-lymphocyte surface antigen precursor CD2

GENE ID SPECIES
449512 Pan troglodytes
493790 Felis catus
677855 Macaca mulatta
768858 Gallus gallus
100126712 Papio anubis
100598578 Nomascus leucogenys
12481 Mus musculus
914 Homo sapiens
497761 Rattus norvegicus
497022 Bos taurus
101106727 Ovis aries
396662 Sus scrofa
100034205 Equus caballus
607448 Canis lupus familiaris
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