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anti-CD46 Molecule, Complement Regulatory Protein (CD46) Antibodies

The protein encoded by CD46 is a type I membrane protein and is a regulatory part of the complement system. Additionally we are shipping CD46 Molecule, Complement Regulatory Protein Proteins (28) and CD46 Molecule, Complement Regulatory Protein Kits (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD46 822 P40121
CD46 17221 O88174
CD46 29333 Q9Z0M4
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Top anti-CD46 Molecule, Complement Regulatory Protein Antibodies at antibodies-online.com

Showing 10 out of 263 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IHC (fro), IP, WB Table 1. Tissue distribution of CD46 (Johnstone et al., modified) 0.2 mg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of CD46 Antibody (C-term) (ABIN650982) in CEM ce... CD46 Antibody (C-term) (ABIN650982) immunohistochemistry analysis in f... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IP, WB Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN C... 0.2 mg Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated IP, IHC (p), ELISA Immunochemical staining of human CD46 in human placenta with rabbit po... 100 μg Log in to see 16 Days
$218.90
Details
Human Mouse Biotin FACS Surface staining of human peripheral blood cells with anti-CD46 (MEM-2... 0.1 mg Log in to see 4 to 5 Days
$288.75
Details
Cow Mouse Biotin FACS   0.1 mg Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated FACS, IP, WB Surface staining of human peripheral blood cells with anti-CD46 (MEM-2... 0.1 mg Log in to see 4 to 5 Days
$242.55
Details
Cow Mouse Un-conjugated FACS, IP, WB   0.1 mg Log in to see 6 to 8 Days
$286.00
Details
Human Mouse FITC FACS Surface staining of human peripheral blood cells with anti-CD46 (MEM-2... 100 Tests Log in to see 4 to 5 Days
$288.75
Details
Human Mouse APC FACS Surface staining of human peripheral blood cells with anti-CD46 (MEM-2... 100 Tests Log in to see 4 to 5 Days
$334.95
Details

CD46 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-CD46 Molecule, Complement Regulatory Protein Antibodies

  1. Cow (Bovine) Monoclonal CD46 Primary Antibody for FACS, IP - ABIN616770 : Gaggar, Shayakhmetov, Lieber: CD46 is a cellular receptor for group B adenoviruses. in Nature medicine 2003 (PubMed)
    Show all 14 references for ABIN616770

  2. Cow (Bovine) Monoclonal CD46 Primary Antibody for FACS - ABIN616771 : Liszewski, Kemper, Price, Atkinson: Emerging roles and new functions of CD46. in Springer seminars in immunopathology 2005 (PubMed)
    Show all 14 references for ABIN616771

  3. Human Monoclonal CD46 Primary Antibody for FACS - ABIN94151 : Oliaro, Pasam, Waterhouse, Browne, Ludford-Menting, Trapani, Russell: Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 14 references for ABIN94151

  4. Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN94149 : Marie, Astier, Rivailler, Rabourdin-Combe, Wild, Horvat: Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation. in Nature immunology 2002 (PubMed)
    Show all 13 references for ABIN94149

  5. Human Monoclonal CD46 Primary Antibody for FACS - ABIN94152 : Okada, Liszewski, Atkinson, Caparon: Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Show all 12 references for ABIN94152

  6. Human Monoclonal CD46 Primary Antibody for FACS - ABIN192263 : Kälin, Amstutz, Gastaldelli, Wolfrum, Boucke, Havenga, DiGennaro, Liska, Hemmi, Greber: Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35. in Journal of virology 2010 (PubMed)
    Show all 12 references for ABIN192263

  7. Human Monoclonal CD46 Primary Antibody for FACS, IHC (fro) - ABIN111918 : Johnstone, Russell, Loveland, McKenzie: Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing. in Molecular immunology 1993 (PubMed)
    Show all 5 references for ABIN111918

  8. Human Polyclonal CD46 Primary Antibody for FACS, IF - ABIN650982 : Weyand, Calton, Higashi, Kanack, So: Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infection. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN650982

  9. Human Polyclonal CD46 Primary Antibody for IP, IHC (p) - ABIN1999639 : Miyaji, Paul, Shahrizaila, Umapathi, Yuki: Complement regulatory proteins (CD46, 55 and 59) expressed on Schwann cells: immune targets in demyelinating neuropathies? in Journal of neuroimmunology 2014 (PubMed)

  10. Human Monoclonal CD46 Primary Antibody for FACS, IP - ABIN119580 : Sirena, Lilienfeld, Eisenhut, Kälin, Boucke, Beerli, Vogt, Ruedl, Bachmann, Greber, Hemmi: The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3. in Journal of virology 2004 (PubMed)

More Antibodies against CD46 Molecule, Complement Regulatory Protein Interaction Partners

Human CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. CD46 controls both Th1 (show TH1L Antibodies) activation and regulation via a miR (show MLXIP Antibodies)-150-dependent mechanism.

  2. The composite biomarker, CAPG (show NCAPG Antibodies) and GIPC1 (show GIPC1 Antibodies) in primary breast tumors, predicted disease outcomes and benefit from zoledronate and may facilitate patient selection for adjuvant bisphosphonate treatment.

  3. Data show that CD28 antigen (show CD28 Antibodies) costimulation modulates CD46 antigen surface expression on activated T cells.

  4. This review summarizes our current knowledge of disease-associated mutations in this complement inhibitor(CD46).

  5. It was not discover any association between A304V or other CD46 SNPs and preeclampsia.

  6. gene deficiency results in defective Th1 (show TH1L Antibodies) cell induction due to failure in metabolic reprogramming

  7. Each mutant C3b bound MCP at reduced affinity, providing a molecular basis for its reduced cofactor activity in atypical hemolytic uremic syndrome.

  8. The mutations in the regulators CFH (show CFH Antibodies), CFI (show CFI Antibodies) and MCP involve loss-of-function, whereas those for C3 involve gain-of-function.

  9. Results suggest a possible role for multidrug resistance genes ABCA10 (show ABCA10 Antibodies) and ABCA6 (show ABCA6 Antibodies) in follicular lymphoma survival and add to the evidence that genetic variation in CD46 and IL8 (show IL8 Antibodies) may have prognostic implications follicular lymphoma.

  10. Expression of membrane complement regulators, CD46, CD55 (show CD55 Antibodies) and CD59 (show CD59 Antibodies), in mesothelial cells of patients on peritoneal dialysis therapy.

Mouse (Murine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. Changes in CD46 expression may lead to changes in VEGF and play a pathologic role in the development of age-related macular degeneration.

  2. Our findings provide evidence for expression of CD46 in the mouse eye and a role for CD46 in protection against laser-induced choroidal neovascularization

  3. This fusion is mediated by the interaction between viral glycoproteins expressed on the membrane of the infected cells and CD46 on the glial targets, and is also observed using cells expressing recombinant MV glycoproteins.

  4. CD46 isoforms function as receptors for human herpesvirus 6 and measles virus

  5. Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm and increased male fertility

  6. CD46 has a role as a receptor for fusion and entry of human herpesvirus 6 into target cells

Cow (Bovine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. Study shows the existence of 10 distinct allelic versions of the CCP1 (show AGTPBP1 Antibodies) module of CD46; ectopic expression of the 10 bovine CD46 isoforms rendered the PK15 cells permissive to bovine viral diarrhea virus.

  2. localization of CD46 on bovine sperm membrane

Pig (Porcine) CD46 Molecule, Complement Regulatory Protein (CD46) interaction partners

  1. The results obtained in this study showed that both porcine CD46 and heparan sulfates play a major role in the initial steps of classical swine fever virus infection.

CD46 Molecule, Complement Regulatory Protein (CD46) Antigen Profile

Protein Summary

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with CD46

  • capping protein (actin filament), gelsolin-like (CAPG) antibody
  • CD46 antigen, complement regulatory protein (Cd46) antibody
  • CD46 molecule, complement regulatory protein (CD46) antibody
  • CD46 molecule, complement regulatory protein (Cd46) antibody
  • Membrane cofactor protein-like (LOC100341359) antibody
  • AFCP antibody
  • AHUS2 antibody
  • Mcp antibody
  • MIC10 antibody
  • TLX antibody
  • TRA2.10 antibody

Protein level used designations for CD46

actin regulatory protein CAP-G , actin-regulatory protein CAP-G , gelsolin-like capping protein , macrophage capping protein , macrophage-capping protein , membrane cofactor protein , membrane cofactor protein(GMP1-full) , CD46 antigen, complement regulatory protein , antigen identified by monoclonal antibody TRA-2-10 , complement membrane cofactor protein , measles virus receptor , membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) , trophoblast leucocyte common antigen , trophoblast leukocyte common antigen , trophoblast-lymphocyte cross-reactive antigen , brain microvascular membrane cofactor

GENE ID SPECIES
822 Homo sapiens
17221 Mus musculus
100135498 Cavia porcellus
4179 Homo sapiens
616002 Bos taurus
280851 Bos taurus
396922 Sus scrofa
29333 Rattus norvegicus
100341359 Oryctolagus cuniculus
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