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CD79a Molecule, Immunoglobulin-Associated alpha Proteins (CD79A)

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Additionally we are shipping CD79a Molecule, Immunoglobulin-Associated alpha Antibodies (460) and CD79a Molecule, Immunoglobulin-Associated alpha Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD79A 12518 P11911
CD79A 973 P11912
Rat CD79A CD79A 681236  
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Top CD79a Molecule, Immunoglobulin-Associated alpha Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Mouse ECD,Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,203.67
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,234.83
Details
HOST_HEK-293 Cells Human His-DYKDDDDK-Strep II Tag   25 μg Log in to see 11 to 12 Days
$883.68
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

CD79A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
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Human , , , ,
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More Proteins for CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) Interaction Partners

Mouse (Murine) CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) interaction partners

  1. BCR (show BCR Proteins) activation is accompanied by asymmetric conformational changes, possibly promoting the binding of Igalpha and Igbeta to differently localized signaling complexes

  2. CD79a myeloid cells showed enhanced ability to promote primary tumor growth and metastasis.

  3. Data indicate that in the absence of DGKzeta (show DGKZ Proteins), the threshold for B cell antigen receptor (BCR (show BCR Proteins)) signaling, measured as activation of the Ras-extracellular signal-regulated kinase (ERK (show EPHB2 Proteins)) pathway, was markedly reduced in mature follicular B cells.

  4. Data show that the B cell antigen receptor (BCR (show BCR Proteins)) and Igalpha may be required for B cell survival because they function as adaptor proteins in a BAFFR (show TNFRSF13C Proteins) signaling pathway leading to activation of Syk (show SYK Proteins), indicating crosstalk between the two receptors.

  5. The mouse B cell-specific mb-1 (show PSMB5 Proteins) gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.

  6. endocytosed BCR (show BCR Proteins) sequentially regulates MAPK (show MAPK1 Proteins) and Akt (show AKT1 Proteins) signaling pathways from intracellular compartments

  7. Arginine 198 in the tail of the Igalpha subunit of the BCR (show BCR Proteins) is methylated by the protein arginine methyltransferase 1 (show PRMT1 Proteins). Methylation negatively regulates the calcium and PI-3 (show PI3 Proteins) kinase pathways of the BCR (show BCR Proteins), promoting signals leading to B (show TDO2 Proteins) cell differentiation.

  8. The direct recruitment of BLNK (show BLNK Proteins) to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

  9. IgA deficiency in lymphotoxin-deficient (LT(-/-)) mice could be fully reversed by reconstitution with LT-expressing bone marrow, despite the absence of both LNs and PPs.

  10. The VHDJH recombination process at the IgH locus and the survival of pro-B cells that carry these rearrangements do not depend on the expression of Ig-alpha molecules.

Human CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) interaction partners

  1. Data show that Bruton tyrosine kinase (BTK (show BTK Proteins))inhibitor Ibrutinib augments MALT lymphoma associated translocation (show MALT1 Proteins) protein (MALT1 (show MALT1 Proteins)) inhibition by S-Mepazine in CD79 antigen mutant activated B cell-subtype (ABC (show ABCB6 Proteins)) of diffuse large B cell lymphoma (DLBCL).

  2. Phosphorylation of CD79a causes a decrease in helical propensity in the C-terminal region, for CD79b (show CD79B Proteins), the opposite was observed and phosphorylation resulted in an increase of helical propensity in the C-terminal part.

  3. High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase (show LPO Proteins).

  4. CD79a plays a functional role in the tumor promoting effects of myeloid cells, and may represent a novel target for cancer therapy.

  5. STN (show EEF1A2 Proteins) produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.

  6. CD79a may be helpful marker in the differential diagnosis of classical Hodgkin's lymphoma and primary mediastinal B-cell lymphoma

  7. Unlike the B29 (show CD79B Proteins) octamer motif, the mb-1 (show PSMB5 Proteins) octamer motif does not have the essential sequence required for OBF-1/Bob1 (show POU2AF1 Proteins) interaction, therefore its promoter is not transactivated by OBF-1/Bob1 (show POU2AF1 Proteins).

  8. B cell-restricted mb-1 (show PSMB5 Proteins) gene: expression, function, and lineage infidelity. Review.

  9. Results indicate that PAX5 (show PAX5 Proteins) is a more specific marker than CD79a for B-cell ALL diagnosis.

  10. lower levels of B-cell receptor surface expression observed in chronic lymphocytic leukemia are accounted for by an impaired glycosylation and folding of the mu and CD79a chains.

CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) Protein Profile

Protein Summary

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with CD79A

  • CD79a molecule, immunoglobulin-associated alpha (CD79A)
  • CD79A antigen (immunoglobulin-associated alpha) (Cd79a)
  • CD79a molecule, immunoglobulin-associated alpha (Cd79a)
  • Cd79a molecule, immunoglobulin-associated alpha (Cd79a)
  • CD79A protein
  • IG-alpha protein
  • IGA protein
  • Igalpha protein
  • Ly-54 protein
  • Ly54 protein
  • MB-1 protein

Protein level used designations for CD79A

CD79a molecule, immunoglobulin-associated alpha , B-cell antigen receptor complex-associated protein alpha chain , Ig alpha , MB-1 membrane glycoprotein , immunoglobulin-associated alpha , membrane-bound immunoglobulin-associated protein , surface IgM-associated protein , CD79a antigen (immunoglobulin-associated alpha) , ig-alpha , CD79-alpha protein , CD79A antigen (immunoglobulin-associated alpha) , B-cell antigen receptor complex-associated protein alpha-chain

GENE ID SPECIES
740560 Pan troglodytes
12518 Mus musculus
973 Homo sapiens
100052219 Equus caballus
100190992 Sus scrofa
281674 Bos taurus
100724815 Cavia porcellus
484483 Canis lupus familiaris
681236 Rattus norvegicus
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