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CDC-Like Kinase 2 Proteins (CLK2)

CLK2 encodes a member of the CLK family of dual specificity protein kinases. Additionally we are shipping CLK2 Antibodies (95) and CLK2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLK2 1196 P49760
CLK2 12748 O35491
Rat CLK2 CLK2 365842  
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Top CLK2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

CLK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for CDC-Like Kinase 2 (CLK2) Interaction Partners

Human CDC-Like Kinase 2 (CLK2) interaction partners

  1. Clk1 (show CDK11B Proteins), Clk2 and Clk4 (show CLK4 Proteins) prevent chromatin breakage by regulating the Aurora B (show AURKB Proteins)-dependent abscission checkpoint.

  2. Loss of CLK2 in luminal breast cancer cells leads to the upregulation of epithelial-to-mesenchymal transition (EMT (show ITK Proteins))-related genes and a switch to mesenchymal splice variants of several genes.

  3. LAMMER/Cdc2 (show CDK1 Proteins)-like kinase, represented by Doa and its mammalian homolog CLK2, is a critical and conserved component in the regulatory program of the mitosis-to-meiosis switch

  4. CLK1 (show CDK11B Proteins) Increases While CLK2 Decreases HIV-1 Gene Expression.

  5. AKT (show AKT1 Proteins) activation controls cell survival to ionizing radiation by phosphorylating CLK2, revealing an important regulatory mechanism required for promoting cell survival.

  6. Cdc2 (show CDK1 Proteins)-like kinases and DNA topoisomerase I (show TOP1 Proteins) regulate alternative splicing of tissue factor (show F3 Proteins) in human endothelial cells.

Mouse (Murine) CDC-Like Kinase 2 (CLK2) interaction partners

  1. Liver-specific Clk2 knockout mice fed a high-fat diet exhibit increased fasting levels of blood ketone bodies, reduced respiratory exchange ratio, and increased gene expression of fatty acid oxidation and ketogenic pathways.

  2. LAMMER/Cdc2 (show CDK1 Proteins)-like kinase, represented by Doa and its mammalian homolog CLK2, is a critical and conserved component in the regulatory program of the mitosis-to-meiosis switch

  3. Cdc2-like kinase 2 (Clk2) directly phosphorylates the SR domain on PGC-1alpha, resulting in repression of gluconeogenic gene expression and hepatic glucose output.

CLK2 Protein Profile

Protein Summary

This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.

Gene names and symbols associated with CDC-Like Kinase 2 Proteins (CLK2)

  • CDC-like kinase 2 (CLK2)
  • CDC-like kinase 2 (clk2)
  • CDC-like kinase 2a (clk2a)
  • CDC-like kinase 2 (Clk2)
  • AU041688 protein
  • clk2 protein
  • fb20c02 protein
  • hCLK2 protein
  • MGC53993 protein
  • MGC131228 protein
  • si:ch211-81a5.7 protein
  • Tu52 protein
  • wu:fb20c02 protein

Protein level used designations for CDC-Like Kinase 2 Proteins (CLK2)

CDC-like kinase 2 , dual specificity protein kinase CLK2 , CLK kinase , Clk2-Scamp3 protein

GENE ID SPECIES
100063546 Equus caballus
379763 Xenopus laevis
457364 Pan troglodytes
496828 Xenopus (Silurana) tropicalis
558981 Danio rerio
734822 Xenopus laevis
1196 Homo sapiens
12748 Mus musculus
365842 Rattus norvegicus
425060 Gallus gallus
100155149 Sus scrofa
490427 Canis lupus familiaris
512737 Bos taurus
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