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CKLF-Like MARVEL Transmembrane Domain Containing 5 Proteins (CMTM5)

CMTM5 belongs to the chemokine-like factor gene superfamily. Additionally we are shipping CMTM5 Antibodies (60) and CMTM5 Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CMTM5 116173 Q96DZ9
CMTM5 67272 Q9D6G9
Rat CMTM5 CMTM5 290214  
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Top CMTM5 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CMTM5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for CKLF-Like MARVEL Transmembrane Domain Containing 5 (CMTM5) Interaction Partners

Human CKLF-Like MARVEL Transmembrane Domain Containing 5 (CMTM5) interaction partners

  1. results indicate that CMTM5 is down-regulated in prostate cancer and exhibit tumor suppressor activities in androgen-independent prostate cancer cells

  2. In the OSCC cell lines CAL27 and GNM, the ectopic expression of CMTM5-v1 strongly inhibited cell proliferation and migration and induced apoptosis.

  3. The reduced expression of CMTM5 correlates significantly with poorly differentiated ovarian cancer and high preoperative CA125 (show MUC16 Proteins) level.

  4. Data suggest that CMTM5 may be involved in the pathomechanism of myeloid leukemias.

  5. The expression level of cmtm5 gene is abnormally lower in the bone marrow cells from the multiple myeloma patients, and are associated with ISS stages.

  6. HER2 (show ERBB2 Proteins) was up regulated in prostate cancer epithelium while CMTM5 was down regulated. Overexpression of CMTM5 in PC3 (show PCSK1 Proteins) cells could lower the HER2 (show ERBB2 Proteins) and Cyclin D1 (show CCND1 Proteins) protein level.

  7. CMTM5-v1 might be secreted via a different vesicle-mediated secretory pathway, which will be helpful for the studies of vesicle-mediated secretion and MARVEL domain-containing proteins.

  8. Bioinformatics based on CKLF2 cDNA and protein sequences in combination with experimental validation identified CKLFSF1-8 gene clusters, between the SCY and the TM4SF (show TSPAN1 Proteins) gene families. The 8 family members were cloned and characterized.

  9. CMTM5 exhibits tumor suppressor activities, but with frequent epigenetic inactivation in carcinoma cell lines

  10. These findings verify that CMTM5-v1 inhibits the growth of CC cell lines via inducing apoptosis.

CMTM5 Protein Profile

Protein Summary

This gene belongs to the chemokine-like factor gene superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Gene names and symbols associated with CMTM5

  • chemokine-like factor superfamily 5 (LOC100346131)
  • CKLF-like MARVEL transmembrane domain containing 5 (CMTM5)
  • CKLF-like MARVEL transmembrane domain containing 5 (Cmtm5)
  • 1500005P16Rik protein
  • 2900052H21Rik protein
  • Cklfsf5 protein

Protein level used designations for CMTM5

CKLF-like MARVEL transmembrane domain-containing protein 5 , chemokine-like factor super family 5 , chemokine-like factor superfamily member 5 , chemokine-like factor super family five variant 4 , chemokine-like factor superfamily 5

GENE ID SPECIES
100346131 Oryctolagus cuniculus
116173 Homo sapiens
67272 Mus musculus
608193 Canis lupus familiaris
100514659 Sus scrofa
510145 Bos taurus
290214 Rattus norvegicus
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