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Associates with the NF-kappa-B complex and suppresses its transcriptional activity (By similarity). Additionally we are shipping COMM Domain Containing 7 Antibodies (19) and COMM Domain Containing 7 Proteins (6) and many more products for this protein.
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High COMMD7 expression was specifically detected in pancreatic ductal adenocarcinoma tissues and pancreatic ductal adenocarcinoma cell lines. In addition, COMMD7 overexpression positively correlated with histological differentiation and tumor node metastasis (TNM (show ODZ1 ELISA Kits)) stage.
The present data suggests a potential role of CXCL10 (show CXCL10 ELISA Kits) in the oncogenic function of COMMD7.
COMMD7's binding to NEMO (show IKBKG ELISA Kits) does not interfere with the binding to the IKKs, and that the disruption of the IKK (show CHUK ELISA Kits) complex through the use of the NBP (show NUBP1 ELISA Kits) competitor impairs the termination of NF-kappaB (show NFKB1 ELISA Kits) activity
COMMD7 contributes to hepatocellular carcinoma progression by reducing cell apoptosis and overcoming cell cycle arrest.
Associates with the NF-kappa-B complex and suppresses its transcriptional activity (By similarity).
COMM domain containing 7
, COMM domain-containing protein 7