C-Type Lectin Domain Family 10, Member A (CLEC10A) ELISA Kits

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC10A Antibodies (136) and CLEC10A Proteins (22) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CLEC10A 10462 Q8IUN9
Anti-Mouse CLEC10A CLEC10A 17312 P49300
Anti-Rat CLEC10A CLEC10A 64195  
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More ELISA Kits for CLEC10A Interaction Partners

Human C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. this paper shows that key gene of intermediate proinflammatory monocytes, such as CLEC10A, is expressed three- to fourfold more in juvenile idiopathic arthritis-enthesitis-related arthritis

  2. BRAF (show BRAF ELISA Kits)(V600E) mutation induces MGL ligand expression, thereby providing a direct link between oncogenic transformation and aberrant expression of immunosuppressive glycans in colorectal neoplasms.

  3. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

  4. expression of GalNAc moieties mirrors the T cell activation status, and thus only highly stimulated T cells are prone to the suppressive action of MGL.

  5. MGL triggering synergized with TLR2 (show TLR2 ELISA Kits)-induced pathways, leading to elevated IL-10 (show IL10 ELISA Kits) mRNA levels & enhanced TNF-alpha (show TNF ELISA Kits) mRNA stability. It promoted phosphorylation of the ERK (show EPHB2 ELISA Kits) & CREB (show CREB1 ELISA Kits), fine-tuning the DC maturation phenotype.

  6. Described is the use of recombinant CLEC10A (CD301), a human glycoreceptor of the C-type lectin (show MBL2 ELISA Kits) family, for the detection of ligands in sections from formalin-fixed, paraffin-embedded normal and cancerous mammary tissues.

  7. MGL engagement improved DC performance as antigen-presenting cells, promoting the upregulation of maturation markers, a decrease in phagocytosis, an enhancement of motility, and most importantly an increase in antigen-specific CD8 (show CD8A ELISA Kits)(+) T-cell activation.

Mouse (Murine) C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia

  2. Mgl1 (show LLGL1 ELISA Kits)-deficient mice displayed accelerated colonic propulsion and were hypersensitive to mu receptor-mediated inhibition of colonic motility.

  3. MGL1 (show LLGL1 ELISA Kits) is involved in T. crassiceps recognition and subsequent innate immune activation and resistance.

  4. The MGL1 (show LLGL1 ELISA Kits) functions as an attachment and entry receptor for influenza A virus.

  5. Syk (show SYK ELISA Kits) was involved in the CLR (show CALCR ELISA Kits)-mediated activation of mast cells by BP

  6. Hoxc8 (show HOXC8 ELISA Kits) downregulates Mgl1 (show LLGL1 ELISA Kits) tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  7. The authors conclude that lectin-mediated interactions of influenza virus with the MMR (show MRC1 ELISA Kits) or the MGL are required for the endocytic uptake of the virus into macrophages.

  8. mMGL1 preferentially binds Lewis X (show FUT4 ELISA Kits)-conjugated soluble polyacrylamides

  9. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.

  10. sialoadhesin (show SIGLEC1 ELISA Kits) acts as an endogenous counter-receptor for MGL1 (show LLGL1 ELISA Kits)

CLEC10A Antigen Profile

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with CLEC10A

  • C-type lectin domain family 10, member A (CLEC10A) antibody
  • C-type lectin domain family 10, member A (Clec10a) antibody
  • CD301 antibody
  • CD301a antibody
  • CLEC10A antibody
  • CLECSF13 antibody
  • CLECSF14 antibody
  • HML antibody
  • HML2 antibody
  • M-ASGP-BP-1 antibody
  • Mgl antibody
  • Mgl1 antibody
  • Mgll antibody

Protein level used designations for CLEC10A

C-type lectin domain family 10, member A , C-type lectin, superfamily member 14 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived) , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) , C-type lectin domain family 10 member A , macrophage lectin 2 (calcium dependent) , macrophage asialoglycoprotein-binding protein 1 , macrophage galactose N-acetyl-galactosamine specific lectin 1 , Gal/GalNAc-specific lectin , M-ASGP-BP , M-ASGP-BP-1 , MMGL , macrophage galactose/N-acetylgalactosamine-specific lectin , monoglyceride lipase

607405 Canis lupus familiaris
748824 Pan troglodytes
10462 Homo sapiens
17312 Mus musculus
64195 Rattus norvegicus
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