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CUE Domain Containing 2 Proteins (CUEDC2)

Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation (By similarity).. Additionally we are shipping CUEDC2 Antibodies (65) and CUEDC2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CUEDC2 79004 Q9H467
CUEDC2 67116 Q9CXX9
CUEDC2 294009 A1L131
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Top CUEDC2 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,693.17
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,740.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,744.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CUEDC2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for CUE Domain Containing 2 (CUEDC2) Interaction Partners

Human CUE Domain Containing 2 (CUEDC2) interaction partners

  1. Results suggest that decreased expression of CUEDC2 contributes to tumor growth in lung adenocarcinoma, leading to a poor clinical outcome.

  2. CUEDC2 plays a crucial role in modulating macrophage function and is associated with both colitis and colon tumorigenesis.

  3. High CUEDC2 sensitizes chronic myeloid leukemic cells to imatinib treatment.

  4. In response to UV irradiation, CUEDC2 undergoes ERK1/2-dependent phosphorylation and ubiquitin-dependent degradation, leading to APC (show APC Proteins)/C(Cdh1 (show CDH1 Proteins))-mediated cyclin A (show CCNA2 Proteins) destruction, cyclin-dependent kinase 2 (show KKIAMRE Proteins) inactivation, and G1 arrest.

  5. a new biological activity for CUEDC2 as the regulator of JAK1 (show JAK1 Proteins)/STAT3 (show STAT3 Proteins) signaling and the mechanism by which SOCS3 (show SOCS3 Proteins) has been linked to suppression of the JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) pathway

  6. CUEDC2 is a cell-cycle regulator that promotes spindle checkpoint inactivation and releases APC (show APC Proteins)/C from checkpoint inhibition. CUEDC2 is phosphorylated by Cdk1 (show CDK1 Proteins) during mitosis.

  7. These results identify a key post-translational mechanism that controls progesterone receptor (show PGR Proteins) protein levels and for the first time provide an important insight into the function of CUEDC2 in breast cancer proliferation.

Mouse (Murine) CUE Domain Containing 2 (CUEDC2) interaction partners

  1. These findings demonstrate that CUEDC2 plays an important role in protection from colonic inflammation, primarily by inhibiting the NF-kappaB (show NFKB1 Proteins) and STAT3 (show STAT3 Proteins) signaling pathways and preventing excessive proliferation of the inflammatory epithelial cell.

  2. CUEDC2 plays a crucial role in modulating macrophage function and is associated with both colitis and colon tumorigenesis.

CUEDC2 Protein Profile

Protein Summary

Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation (By similarity).

Gene names and symbols associated with CUEDC2

  • CUE domain containing 2 (cuedc2-a)
  • CUE domain containing 2 (CUEDC2)
  • CUE domain containing 2 (cuedc2-b)
  • CUE domain containing 2 (cuedc2)
  • CUE domain containing 2 (Cuedc2)
  • 3010002G01Rik protein
  • bA18I14.5 protein
  • C10orf66 protein
  • cuedc2 protein
  • MGC81368 protein
  • wu:fi42e02 protein
  • zgc:92255 protein

Protein level used designations for CUEDC2

CUE domain-containing protein 2-A , mitotic phosphoprotein 38 , CUE domain containing 2 , CUE domain-containing protein 2-B , CUE domain-containing protein 2

GENE ID SPECIES
398317 Xenopus laevis
423761 Gallus gallus
447300 Xenopus laevis
713243 Macaca mulatta
745600 Pan troglodytes
100145279 Xenopus (Silurana) tropicalis
79004 Homo sapiens
67116 Mus musculus
294009 Rattus norvegicus
486861 Canis lupus familiaris
516091 Bos taurus
334351 Danio rerio
Selected quality suppliers for CUEDC2 Proteins (CUEDC2)
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