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Ca++-Dependent Secretion Activator 2 (CADPS2) ELISA Kits

CADPS2 encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Additionally we are shipping CADPS2 Antibodies (16) and CADPS2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CADPS2 CADPS2 26989 Q62717
CADPS2 93664 Q86UW7
CADPS2 320405 Q8BYR5
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Top CADPS2 ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for CADPS2 Interaction Partners

Human Ca++-Dependent Secretion Activator 2 (CADPS2) interaction partners

  1. Mutation screening of 187 patients with autism spectrum disorders and 36 with intellectual disability identified a missense change of maternal origin disrupting CADPS2/D2DR (show DRD2 ELISA Kits) interaction.

  2. We speculate that haploinsufficiency of CADPS2 contributes to ASDs.

  3. identification, cloning, and comparative characterization of a second mammalian CAPS (show CAPS ELISA Kits) isoform, CAPS2 (show CAPS2 ELISA Kits); concluded that at the functional level, CAPS2 (show CAPS2 ELISA Kits) is largely redundant with CAPS1 (show CAPS ELISA Kits)

  4. Results from Cadps2-deficient mice and human data suggest that a disturbance in CADPS2-mediated neurotrophin release contributes to autistic-like cellular and behavioral phenotypes.

  5. CAPS (show CAPS ELISA Kits) proteins are involved in optimizing vesicular monoamine uptake and storage mediated by VMAT1 (show SLC18A1 ELISA Kits) and VMAT2 (show Slc18a2 ELISA Kits)

Mouse (Murine) Ca++-Dependent Secretion Activator 2 (CADPS2) interaction partners

  1. CAPS2 plays an important role in subcellular locality (axonal vs. somato (show SSTR5 ELISA Kits)-dendritic) of enhanced BDNF (show BDNF ELISA Kits) and NT-3 (show NTF3 ELISA Kits) release, which is indispensable for proper development of postnatal cerebellum.

  2. Data suggest that adequate levels of CAPS2 are critical for normal brain development and normal behavior; allelic changes due to copy number variation may contribute to autistic behavior.

  3. Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF (show BDNF ELISA Kits) and causes autistic-like behavior in mice

  4. identification, cloning, and comparative characterization of a second mammalian CAPS (show CAPS ELISA Kits) isoform, CAPS2; concluded that at the functional level, CAPS2 is largely redundant with CAPS1 (show CAPS ELISA Kits)

  5. results suggest that CAPS2 mediates the depolarization-dependent release of NT-3 (show NTF3 ELISA Kits) and BDNF (show BDNF ELISA Kits) from granule cells, leading to regulation in cell differentiation and survival during cerebellar development

  6. CADPS2-KO mice show autistic-like phenotypes. Moreover, the results show that some autistic patients have an aberrant splicing variant of CADPS2 mRNA, suggesting that a disturbance in CADPS2-mediated neurotrophin (show BDNF ELISA Kits) release contributes to autism.

  7. CADPS2/CAPS2-knockout mice exhibit pronounced impairments in cerebellar development and functions. These results are also suggestive of an involvement of the CADPS2/CAPS2 gene, which is located within the AUTS1, in the cerebellar deficits of autism.

  8. The results show the immunohistochemical localization of the CAPS (show CAPS ELISA Kits) family proteins in various mouse tissues.

  9. The two CAPS (show CAPS ELISA Kits) family proteins are complementarily distributed throughout the various brain regions of mice.

CADPS2 Antigen Profile

Antigen Summary

This gene encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CADPS2

  • Ca++-dependent secretion activator 2 (CADPS2) antibody
  • Ca++-dependent secretion activator (Cadps) antibody
  • Ca++-dependent secretion activator 2 (Cadps2) antibody
  • Ca2+-dependent activator protein for secretion 2 (Cadps2) antibody
  • A230044C21Rik antibody
  • Caps antibody
  • Caps-2 antibody
  • Caps1 antibody
  • Caps2 antibody
  • Cpd2 antibody
  • RGD1559440 antibody

Protein level used designations for CADPS2

Ca2+-dependent activator protein for secretion 2 , Ca++-dependent secretion activator 2 , CAPS-1 , Ca2+-dependent activator protein , Ca2+-dependent secretion activator , Ca<2+-dependent activator protein for secretion , calcium-dependent activator protein for secretion 1 , calcium-dependent secretion activator 1 , rCAPS , CAPS-2 , calcium-dependent activator protein for secretion 2 , calcium-dependent secretion activator 2 , cerebellum postnatal development associated protein 2

GENE ID SPECIES
100056300 Equus caballus
472494 Pan troglodytes
26989 Rattus norvegicus
93664 Homo sapiens
312166 Rattus norvegicus
475304 Canis lupus familiaris
100525671 Sus scrofa
519444 Bos taurus
320405 Mus musculus
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