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CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Additionally we are shipping CDH16 Antibodies (19) and and many more products for this protein.
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Mutations in CDH17 gene is associated with idiopathic hypereosinophilic syndrome.
Review/Meta-analysis: data reflect the role of CDH17 in tumor proliferation and metastasis among gastric cancer patients.
CDH17 is a sensitive (81%) and highly specific (100%) marker for metanephric adenoma.
RGD motif present in cadherin 17 induces integrin activation and tumor growth
Data suggest that combined tumor expression of CDH17 (cadherin-17) and SATB2 (special AT-rich sequence binding protein 2 (show SATB2 Proteins)) may be used as diagnostic biomarkers in subjects with medullary carcinoma of the large intestine (colon; cecum).
Data reveal a new function for CDH17, which is to regulate alpha2beta1 integrin signaling in cell adhesion and proliferation in colon cancer cells for liver metastasis.
The SNPs of the CDH17 gene c.2216 A>C might be clinically important in the prognosis of colorectal carcinoma.
This study demonstrates that the secreted form of cadherin-17 (ectodomain) is truncated at the C-terminus.
results identify CDH17 as a biomarker of gastric carcinoma and attractive therapeutic target for this aggressive malignancy.
Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFkappaB signaling pathway.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
, kidney-specific cadherin
, HPT-1 cadherin
, LI cadherin
, human intestinal peptide-associated transporter HPT-1
, human peptide transporter 1
, intestinal peptide-associated transporter HPT-1
, liver-intestine cadherin