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Cadherin EGF LAG Seven Pass G-Type Receptor 2 Proteins (CELSR2)

The protein encoded by CELSR2 is a member of the flamingo subfamily, part of the cadherin superfamily. Additionally we are shipping CELSR2 Antibodies (45) and CELSR2 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CELSR2 1952 Q9HCU4
Rat CELSR2 CELSR2 83465  
CELSR2 53883  
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Top CELSR2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$803.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details

CELSR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) Interaction Partners

Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) interaction partners

  1. no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2-PSRC1 (show PSRC1 Proteins)-SORT1 (show SORT1 Proteins) and the risk of coronary artery disease or ischemic stroke

  2. CELSR2 in the cholesterol gene cluster shows a significant association with coronary artery disease and its single nucleotide polymorphism regulates plasma cholesterol levels.

  3. The novel CAD-associated locus in the vicinity of the PSRC1 and CELSR2 genes on chromosome 1 probably enhances CAD risk through an effect on plasma LDL cholesterol.

Mouse (Murine) Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) interaction partners

  1. The first signal, controlled by cadherin, EGF (show EGF Proteins)-like, laminin G-like, seven-pass, G-type receptor (Celsr) 2, Celsr3 (show CELSR3 Proteins), Frizzled3 (Fzd3 (show FZD3 Proteins)) and Van Gogh (show VANGL2 Proteins) like2 (Vangl2 (show VANGL2 Proteins)) organizes multicilia in individual cells (single-cell polarity)

  2. Celsr2-3 and Fzd3 regulate axonal navigation in the forebrain by using mechanisms different from classical epithelial core planar cell polarity, and require interacting partners other than Vangl1-2 that remain to be identified.

  3. Study shows Flamingo (Fmi) and Frizzled (Fz) 8, members of noncanonical Wnt signaling, both express in and functionally maintain quiescent long-term hematopoietic stem cells.

  4. Celsr2 and Celsr3 (show CELSR3 Proteins) control the development and function of ependymal cilia; findings suggest that planar cell polarity signaling is involved in ependymal cilia development and in the pathophysiology of hydrocephalus, and possibly other ciliopathies

  5. Developmental expression profiles of Celsr (Flamingo) genes in the mouse

  6. Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development

  7. Upregulation of Flamingo1/Celsr2 gene expression in both early and chronic phases of enlargement in the granule cells of the hypertrophic dentate gyrus may correlate mouse Flamingo1/Celsr2 to the development of hippocampal sclerosis.

CELSR2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins\; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Gene names and symbols associated with CELSR2

  • cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) (CELSR2)
  • cadherin, EGF LAG seven-pass G-type receptor 2 (CELSR2)
  • cadherin, EGF LAG seven-pass G-type receptor 2 (Celsr2)
  • cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) (Celsr2)
  • CDHF10 protein
  • EGFL2 protein
  • flamingo protein
  • Flamingo1 protein
  • Megf3 protein
  • mfmi1 protein
  • mKIAA0279 protein

Protein level used designations for CELSR2

EGF-like protein 2 , EGF-like-domain, multiple 2 , cadherin EGF LAG seven-pass G-type receptor 2 , cadherin family member 10 , cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) , epidermal growth factor-like 2 , epidermal growth factor-like protein 2 , flamingo homolog 3 , multiple EGF-like domains protein 3 , multiple epidermal growth factor-like domains 3 , multiple epidermal growth factor-like domains protein 3 , Flamingo1 , cadherin EGF LAG seven-pas G-type receptor 2 , flamingo-like protein celsr2 , seven-pass transmembrane cadherin , flamingo homolog

GENE ID SPECIES
100061311 Equus caballus
1952 Homo sapiens
83465 Rattus norvegicus
53883 Mus musculus
479916 Canis lupus familiaris
538194 Bos taurus
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