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Calcium Homeostasis Modulator 1 Proteins (CALHM1)

CALHM1 encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. Additionally we are shipping CALHM1 Antibodies (37) and CALHM1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CALHM1 255022 Q8IU99
Rat CALHM1 CALHM1 499367  
CALHM1 546729  
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Top CALHM1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

CALHM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Calcium Homeostasis Modulator 1 (CALHM1) Interaction Partners

Human Calcium Homeostasis Modulator 1 (CALHM1) interaction partners

  1. In the presence of antibody, P86L-CALHM1 shifts the balance between neurodegeneration and neuronal survival toward the stimulation of pro-cytotoxic pathways, thus potentially contributing to its deleterious effects in Alzheimer's disease.

  2. CALHM1 polymorphism may be potential biomarker in patients with Alzheimer disease. [meta-analysis]

  3. The rare R154H variant interferes with CALHM1 control of cytosolic Ca2 (show CA2 Proteins)+ and Abeta (show APP Proteins) accumulation.

  4. CALHM1 p.P86L variation may not be an AD susceptibility factor in the Han Chinese population.

  5. This study showed that No association between polymorphisms in the calcium homeostasis modulator 1 gene and mesial temporal lobe epilepsy risk in a Chinese population

  6. rare genetic variants in CALHM1 lead to Ca(2 (show CA2 Proteins)+) dysregulation and may contribute to the risk of EOAD through a mechanism independent from the classical Ass (show ASS1 Proteins) cascade.

  7. The study identifies a previously uncharacterized mechanism of control of Ca(2 (show CA2 Proteins)+)-dependent ERK1/2 signaling in neurons, and further establishes CALHM1 as a critical ion channel for neuronal signaling and function.

  8. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins.

  9. CALHM1 is a voltage-gated ATP-release channel required for sweet, bitter and umami taste perception

  10. An association between the CALHM1 polymorphism and the risk for Alzheimer's disease, was not detected.

Mouse (Murine) Calcium Homeostasis Modulator 1 (CALHM1) interaction partners

  1. Abeta (show APP Proteins) level reduction by CALHM1 could be explained by an increase in extracellular Abeta (show APP Proteins) degradation by insulin-degrading enzyme (show IDE Proteins).

  2. Multiple transduction pathways make complex, concentration-dependent contributions to salty taste perception. One of these pathways depends on CALHM1 to detect hypertonic NaCl in the mouth and signal the aversive taste of concentrated salt.

  3. This study demonistrated that the Calhm1 knockot mice consumed only half as much sugar per day as did Wild type mice.

  4. The study identifies a previously uncharacterized mechanism of control of Ca(2 (show CA2 Proteins)+)-dependent ERK1/2 signaling in neurons, and further establishes CALHM1 as a critical ion channel for neuronal signaling and function.

  5. Calhm1 was of rare abundance in brain tissues

  6. Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins.

  7. CALHM1 is a voltage-gated ATP-release channel required for sweet, bitter and umami taste perception

  8. CALHM1 is an evolutionarily conserved ion channel family that detects membrane voltage and extracellular Ca(2 (show CA2 Proteins)+) levels and plays a role in cortical neuronal excitability and Ca(2 (show CA2 Proteins)+) homeostasis

CALHM1 Protein Profile

Protein Summary

This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.

Gene names and symbols associated with CALHM1

  • calcium homeostasis modulator 1 (CALHM1)
  • novel protein similar to vertebrate calcium homeostasis modulator protein family (LOC557535)
  • calcium homeostasis modulator 1 (LOC100349950)
  • calcium homeostasis modulator 1 (Calhm1)
  • EG546729 protein
  • Fam26c protein
  • RGD1564891 protein

Protein level used designations for CALHM1

calcium homeostasis modulator 1 , novel protein similar to vertebrate calcium homeostasis modulator protein family , calcium homeostasis modulator protein 1 , family with sequence similarity 26, member C

GENE ID SPECIES
466194 Pan troglodytes
486871 Canis lupus familiaris
532026 Bos taurus
557535 Danio rerio
100349950 Oryctolagus cuniculus
100069751 Equus caballus
100601788 Nomascus leucogenys
255022 Homo sapiens
499367 Rattus norvegicus
546729 Mus musculus
428977 Gallus gallus
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