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Calpain 6 Proteins (CAPN6)

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Additionally we are shipping Calpain 6 Antibodies (52) and Calpain 6 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CAPN6 827 Q9Y6Q1
CAPN6 12338 O35646
CAPN6 83685 O88501
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Top Calpain 6 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 13 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CAPN6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Calpain 6 (CAPN6) Interaction Partners

Human Calpain 6 (CAPN6) interaction partners

  1. syndecan-2 (show SDC2 Proteins) exerts its pro-apoptotic function through modulation of the endothelin-1 (show EDN1 Proteins)/NFkappaB (show NFKB1 Proteins) signaling and through downregulation of calpain-6.

  2. results indicated that calpain 6 supported tumorigenesis by inhibiting apoptosis and facilitating angiogenesis. To our knowledge, this result is the first evidence implicating calpain 6 in tumorigenesis

Mouse (Murine) Calpain 6 (CAPN6) interaction partners

  1. These results collectively showed that a loss of CAPN6 promotes skeletal muscle differentiation during both development and regeneration, suggesting a novel physiological function of CAPN6 as a suppressor of skeletal muscle differentiation.

  2. CAPN6 acts as a regulator of Rac1 and cell motility through interaction with GEF-H1 (show ARHGEF2 Proteins).

  3. Capn6 promotes cytoskeletal organization and microtubule stability in osteoclasts.

  4. Capn6 is a microtubule-stabilizing protein expressed in embryonic tissues that may be involved in the regulation of microtubule dynamics and cytoskeletal organization.

Calpain 6 (CAPN6) Protein Profile

Protein Summary

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Gene names and symbols associated with Calpain 6 Proteins (CAPN6)

  • calpain 6 (CAPN6)
  • calpain 6 (LOC100348781)
  • calpain 6 (Capn6)
  • CalpM protein
  • CANPX protein
  • CAPN6 protein
  • CAPNX protein
  • DJ914P14.1 protein

Protein level used designations for Calpain 6 Proteins (CAPN6)

calpain 6 , calpain-6 , calpain-6-like , calpain-like protease X-linked , calpamodulin

422341 Gallus gallus
465810 Pan troglodytes
492068 Canis lupus familiaris
539360 Bos taurus
100054264 Equus caballus
100348781 Oryctolagus cuniculus
100414757 Callithrix jacchus
100445314 Pongo abelii
100480750 Ailuropoda melanoleuca
100522971 Sus scrofa
100593880 Nomascus leucogenys
827 Homo sapiens
12338 Mus musculus
83685 Rattus norvegicus
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