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The product of CASC3 is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). Additionally we are shipping Cancer Susceptibility Candidate 3 Proteins (5) and many more products for this protein.
Showing 10 out of 90 products:
Human Polyclonal CASC3 Primary Antibody for EIA, IHC (p) - ABIN359493
Macchi, Kroening, Palacios, Baldassa, Grunewald, Ambrosino, Goetze, Lupas, St Johnston, Kiebler: Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA-dependent manner. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2003
Show all 2 references for ABIN359493
Human Polyclonal CASC3 Primary Antibody for EIA, IHC (p) - ABIN359492
Degot, Régnier, Wendling, Chenard, Rio, Tomasetto: Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer. in Oncogene 2002
Show all 2 references for ABIN359492
Human Polyclonal CASC3 Primary Antibody for WB - ABIN2785902
Baguet, Degot, Cougot, Bertrand, Chenard, Wendling, Kessler, Le Hir, Rio, Tomasetto: The exon-junction-complex-component metastatic lymph node 51 functions in stress-granule assembly. in Journal of cell science 2007
MLN51, alone or as part of the EJC, interacts directly with the pivotal eukaryotic translation initiation factor (show EIF2A Antibodies) eIF3 (show EIF3A Antibodies)
MLN51 is a key factor in fibroblast-like synoviocyte hyperplasia of rheumatoid arthritis patients.
data demonstrate that metastatic lymph node(MLN)51 protein associates with exon junction complex in the nucleus and remains stably associated with messenger RNA in the cytoplasm
crystal structure of a tetrameric exon junction core complex containing the DEAD-box adenosine triphosphatase eukaryotic initiation factor 4AIII (show EIF4A3 Antibodies) bound to an ATP analog, MAGOH (show MAGOH Antibodies), Y14 (show RBM8A Antibodies), a fragment of MLN51, and a polyuracil mRNA mimic
MLN51 is recruited into cytoplasmic aggregates known as stress granules (SGs (show FBN1 Antibodies)) together with the SG-resident proteins.
data suggest that the mRNA transport machinery is conserved during evolution, and that mammalian Btz is an additional component of the dendritic ribonucleoprotein particles in hippocampal neurons
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.
metastatic lymph node 51
, cancer susceptibility candidate 3
, Cancer susceptibility candidate gene 3 protein homolog
, Metastatic lymph node protein 51 homolog
, Protein MLN 51 homolog
, protein CASC3
, MLN 51
, cancer susceptibility candidate gene 3 protein
, metastatic lymph node gene 51 protein
, protein barentsz
, MLN 51 homolog
, cancer susceptibility candidate gene 3 protein homolog
, metastatic lymph node gene 51 protein homolog
, barentsz protein
, metastatic lymph node protein 51 homolog
, protein MLN 51 homolog