Carbonyl Reductase 3 Proteins (CBR3)

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. Additionally we are shipping CBR3 Antibodies (77) and CBR3 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CBR3 874 O75828
CBR3 109857 Q8K354
Rat CBR3 CBR3 304078  
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Top CBR3 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 2 to 3 Days
$3,035.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$672.00
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

CBR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Top referenced CBR3 Proteins

  1. Human CBR3 Protein expressed in Escherichia coli (E. coli) - ABIN2006310 : Lakhman, Ghosh, Blanco: Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3). in Drug metabolism and disposition: the biological fate of chemicals 2005 (PubMed)
    Show all 2 references for 2006310

  2. Human CBR3 Protein expressed in Escherichia coli (E. coli) - ABIN667118 : Miura, Nishinaka, Terada: Importance of the substrate-binding loop region of human monomeric carbonyl reductases in catalysis and coenzyme binding. in Life sciences 2009 (PubMed)
    Show all 2 references for 667118

  3. Human CBR3 Protein expressed in Wheat germ - ABIN1348188 : Bains, Karkling, Lubieniecka, Grigliatti, Reid, Riggs: Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism. in The Journal of pharmacology and experimental therapeutics 2010 (PubMed)

More Proteins for Carbonyl Reductase 3 (CBR3) Interaction Partners

Human Carbonyl Reductase 3 (CBR3) interaction partners

  1. No significant correlation between cardiotoxicity and SNPs within the CBR (show CBR1 Proteins) pathway. Further investigation into CBR (show CBR1 Proteins) SNPs in a larger adult sample is needed.

  2. association of SNPs in ABCB1 (show ABCB1 Proteins) and CBR3 with chronic cardiotoxicity in a cohort of breast cancer patients treated with anthracyclines.

  3. Variants of CBR3 and GSTP1 (show GSTP1 Proteins) enzymes may be associated with changes in short-term functional cardiac parameters.

  4. genetic polymorphism in the CBR3 gene conferred risk of type 2 diabetes and insulin (show INS Proteins) resistance in Chinese. The association was probably mediated through modulation of adipogenesis.

  5. CBR3 polymorphisms contribute to increased cardiomyopathy risk associated with anthracycline treatment of childhood cancer.

  6. CBR3 is a novel target gene of inflammatory stimuli; elucidation of its detailed role in inflammation deserves further investigation.

  7. Computational searches identify a conserved antioxidant response element(ARE) in the distal carbonyl reductase 3 (CBR3) promoter region.

  8. The CBR3 distal promoter contains an activating cis (show CISH Proteins)-regulatory element that is responsive to Trichostatin A (TSA (show PRDX2 Proteins)) treatment according to promoter reporter assays in HEK (show EPHA3 Proteins) 293 cells.

  9. a physiological role of CBR1 (show CBR1 Proteins), but not for CBR3, in S-nitrosoglutathione reduction and thus ultimately in regulation of NO signaling

  10. CBR3 is regulated via NRF2 (show GABPA Proteins)-dependent signaling pathways, a finding and plays an important role in the cellular response to oxidative stress.

CBR3 Protein Profile

Protein Summary

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

Gene names and symbols associated with Carbonyl Reductase 3 Proteins (CBR3)

  • carbonyl reductase 3 (cbr3)
  • carbonyl reductase 3 (CBR3)
  • carbonyl reductase 3 (Cbr3)
  • 1110001J05Rik protein
  • C81353 protein
  • CBR3 protein
  • hCBR3 protein
  • MGC81473 protein
  • SDR21C2 protein

Protein level used designations for Carbonyl Reductase 3 Proteins (CBR3)

carbonyl reductase 3 , NADPH-dependent carbonyl reductase 3 , carbonyl reductase (NADPH) 3 , carbonyl reductase [NADPH] 3 , short chain dehydrogenase/reductase family 21C, member 2

GENE ID SPECIES
443787 Xenopus laevis
458533 Pan troglodytes
100145008 Xenopus (Silurana) tropicalis
874 Homo sapiens
109857 Mus musculus
304078 Rattus norvegicus
487748 Canis lupus familiaris
100512990 Sus scrofa
516036 Bos taurus
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