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Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 Proteins (CBLL1)

CBLL1 encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. Additionally we are shipping Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 Antibodies (35) and Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CBLL1 104836 Q9JIY2
CBLL1 79872 Q75N03
Rat CBLL1 CBLL1 314028  
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Top Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,386.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,406.33
Details

CBLL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) Interaction Partners

Mouse (Murine) Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) interaction partners

  1. Results suggest that Hakai is an important regulator of cell proliferation and that Hakai may be an oncoprotein and a potential molecular target for cancer treatment.

  2. E-cadherin (show CDH1 Proteins) distribution and expression is altered in utricle epithelia with induction of apoptosis.

Human Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) interaction partners

  1. these observations suggest that the dimeric architecture of the HYB domain is essential for the phosphotyrosine-binding property of Hakai.

  2. By lowering Hakai abundance, miR (show MLXIP Proteins)-203 also reduces Hakai-regulated-cell division.

  3. Hakai dimerization allows the formation of a phosphotyrosine-binding pocket that recognizes specific phosphorylated tyrosines and flanking acidic amino acids of Src (show SRC Proteins) substrates, such as E-cadherin (show CDH1 Proteins), cortactin (show CTTN Proteins) and DOK1 (show DOK1 Proteins).

  4. Hakai mediates E-cadherin (show CDH1 Proteins) ubiquitination and degradation triggered by Slit-Robo signaling during colorectal epithelial cell carcinogenesis.

  5. Together, these data do not support a requirement for CBLL1 during flavivirus entry and rather suggest an essential role of the ubiquitin/proteasome pathway for flavivirus genome amplification.

  6. Results suggest that Hakai is a novel corepressor of ERalpha (show ESR1 Proteins) and may play a negative role in the development and progression of breast cancers.

  7. Results suggest that Hakai is an important regulator of cell proliferation and that Hakai may be an oncoprotein and a potential molecular target for cancer treatment.

Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) Protein Profile

Protein Summary

This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant.

Gene names and symbols associated with CBLL1

  • Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 (CBLL1)
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 (LOC100228392)
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 (LOC100350512)
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 (LOC100358420)
  • Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 (cbll1)
  • Casitas B-lineage lymphoma-like 1 (Cbll1)
  • Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase (CBLL1)
  • Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase (Cbll1)
  • Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 (CBLL1)
  • E3 ubiquitin-protein ligase Hakai (cbll1)
  • AI467391 protein
  • c-Cbl-like protein
  • CBLL1 protein
  • HAKAI protein
  • RNF188 protein
  • zgc:55308 protein

Protein level used designations for CBLL1

E3 ubiquitin-protein ligase Hakai , Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 , E3 ubiquitin-protein ligase Hakai-like , e3 ubiquitin-protein ligase Hakai-like , E-cadherin binding protein E7 , c-Cbl-like protein 1 , casitas B-lineage lymphoma-transforming sequence-like protein 1 , Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 , RING finger protein 188 , Casitas B-lineage lymphoma-like 1

GENE ID SPECIES
524139 Bos taurus
699980 Macaca mulatta
100010322 Monodelphis domestica
100228392 Taeniopygia guttata
100350512 Oryctolagus cuniculus
100358420 Oryctolagus cuniculus
100399104 Callithrix jacchus
100471827 Ailuropoda melanoleuca
394041 Danio rerio
104836 Mus musculus
79872 Homo sapiens
314028 Rattus norvegicus
417701 Gallus gallus
483262 Canis lupus familiaris
734524 Xenopus laevis
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