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CASP14 encodes a member of the cysteine-aspartic acid protease (caspase) family. Additionally we are shipping Caspase 14, Apoptosis-Related Cysteine Peptidase Kits (45) and Caspase 14, Apoptosis-Related Cysteine Peptidase Proteins (14) and many more products for this protein.
Showing 10 out of 85 products:
Human Monoclonal CASP14 Primary Antibody for IF, WB - ABIN393215
Kim, Park, Kim, Lee, Lim, Song, Yoo, Lee: Mutational analysis of caspase genes in prostate carcinomas. in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010
Show all 5 references for ABIN393215
Human Polyclonal CASP14 Primary Antibody for WB - ABIN1686067
Sundararajan, White: E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis. in Journal of virology 2001
Show all 2 references for ABIN1686067
Human Monoclonal CASP14 Primary Antibody for IF, WB - ABIN567789
Pistritto, Jost, Srinivasula, Baffa, Poyet, Kari, Lazebnik, Rodeck, Alnemri: Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. in Cell death and differentiation 2002
Human Monoclonal CASP14 Primary Antibody for ELISA - ABIN1999341
Hu, Snipas, Vincenz, Salvesen, Dixit: Caspase-14 is a novel developmentally regulated protease. in The Journal of biological chemistry 1998
Human Polyclonal CASP14 Primary Antibody for WB - ABIN318746
Park, Kuechle, Choe, Craik, Lawrence, Presland: Expression and characterization of constitutively active human caspase-14. in Biochemical and biophysical research communications 2006
Human Polyclonal CASP14 Primary Antibody for EIA, IHC (p) - ABIN499557
Martinon, Tschopp: Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. in Cell 2004
Mesotrypsin (show PRSS3 Antibodies) generated saposins A-D from prosaposin (show PSAP Antibodies), and mature caspase-14 contributed to this process by activating mesotrypsinogen (show PRSS3 Antibodies) to mesotrypsin (show PRSS3 Antibodies). Knockdown of these proteases markedly down-regulated saposin A synthesis in skin equivalent models.
caspase-14 overexpression is not the cause of utricle formation
Caspase-14-deficient mice are more prone to the development of parakeratosis.
Mere impairment of filaggrin (show FLG Antibodies) degradation by loss of caspase 14 does not influence the inflammatory threshold of atopic dermatitis.
Caspase-14 is required for filaggrin (show FLG Antibodies) degradation to natural moisturizing factors in the skin.
Transcript profiling studies identified caspase (show GATA3 Antibodies)-14 as a novel downstream target of Gata-3, in keeping with its roles in differentiation (show GATA3 Antibodies) and tumorigenesis.
We investigated whether cardiac autonomic control is impaired during sleep in ob/ob mice with morbid obesity caused by congenital leptin (show LEP Antibodies) deficiency.
processing of caspase 14 in epidermal differentiation
SH2-B (show SH2B1 Antibodies) dramatically enhanced leptin (show LEP Antibodies)-stimulated tyrosine phosphorylation of IRS1 (show IRS1 Antibodies) and IRS2 (show IRS2 Antibodies) in human and mouse cells (this is supposed to be a NEWENTRY for mice--SH2-B (show SH2B1 Antibodies)).
Caspase-14, but not caspase-3 (show CASP3 Antibodies) activation coincides temporally and spatially with embryonic KC differentiation, suggesting a role for caspase-14 in terminally differentiated KC.
overexpression of S100A7 (show S100A7 Antibodies) in A431 skin squamous carcinoma cells significantly promoted cell proliferation in vitro and tumor growth in vivo, whereas it suppressed the expression of GATA-3 (show GATA3 Antibodies) and caspase-14
caspase-14 contributes to retinal pigment epithelium cell barrier disruption under hyperglycemic conditions.
Caspase-14 was decreased in inflammatory lesions compared to non-lesion in atopic dermatitis. The amount of caspase-14 in the lesions correlated with clinical severity as determined by eczema area and severity index score and the skin barrier functions.
partial loss of caspase 14 is not associated with dedifferentiation in neoplastic lesions of the oral mucosa
genetic polymorphisms in AICDA (show AICDA Antibodies) and CASP14 are associated with risk for brain tumor in Korean children.
Suggest caspase-14 is a marker of human skin differentiation during development.
Results suggest that caspase-14 may interact with GCM1 (show GCM1 Antibodies) to participate in syncytiotrophoblast differentiation during placental development.
ceramides, an important structural lipid, stimulate caspase-14 expression, coordinating formation of lipid lamellar membranes with the formation of corneocytes
Caspase-14 might play a significant role in the pathogenesis of diabetic retinopathy by accelerating retinal endothelial and epithelial cells death.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
, apoptosis-related cysteine protease
, caspase 14, apoptosis-related cysteine protease