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Cathepsin H Proteins (CTSH)

The protein encoded by CTSH is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. Additionally we are shipping Cathepsin H Antibodies (79) and Cathepsin H Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CTSH 1512 P09668
CTSH 13036 P49935
Rat CTSH CTSH 25425 P00786
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Top Cathepsin H Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Human Un-conjugated   5 μg Log in to see 2 to 3 Days
$199.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Mouse His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,548.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,548.33
Details
HOST_Human Mouse His tag   10 μg Log in to see 5 Days
$203.50
Details
HOST_Human Human Un-conjugated 0.1 mg Log in to see 2 to 3 Days
$792.00
Details
HOST_Human Human Un-conjugated   25 μg Log in to see 7 to 9 Days
$178.21
Details

CTSH Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) , ,

Top referenced Cathepsin H Proteins

  1. Human Cathepsin H Protein expressed in Human - ABIN413149 : Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. in The Journal of biological chemistry 2010 (PubMed)

More Proteins for Cathepsin H (CTSH) Interaction Partners

Human Cathepsin H (CTSH) interaction partners

  1. Especially, rs3825932 in CTSH has integrative functional evidence supporting the association with type 1 diabetes mellitus.

  2. p41 (show EPB41 Proteins) fragment is also shown to reduce the secretion of interleukin-12 (IL-12 (show IL12A Proteins)/p70 (show ANXA6 Proteins)) during the subsequent maturation of treated dendritic cells.

  3. In conclusion, CTSH/rs3825932 and ERBB3 (show ERBB3 Proteins)/rs2292239 SNPs were associated with reduced risk of progression to proliferative diabetic retinopathy and two-step progression of diabetic retinopathy on the ETDRS scale accordingly.

  4. mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2.

  5. The data provide strong evidence that CTSH is an important regulator of beta-cell function during progression of T1D

  6. Quantification of immunohistochemistry showed that there is no difference in the global expression of CTSD (show CTSD Proteins), CTSH and CTSK (show CTSK Proteins) between asthmatics and non-asthmatics.

  7. CtsH-mediated processing of talin might promote cancer cell progression by affecting integrin alphaVbeta3 (show ITGAV Proteins) activation and adhesion strength

  8. The processing of procathepsin H is an autocatalytic, multistep process proceeding from an inactive 41kDa (show GPM374 Proteins) pro-form, through a 30kDa (show SAP30 Proteins) intermediate form, to the 28kDa mature form.

  9. CTSH overexpression in a subset hepatoma may be thyroid hormone receptor (show THRA Proteins) dependent and suggests that this overexpression has an important role in hepatoma progression.

  10. production of cathepsins B and H by tumor cells along with concomitant decrease of their inhibitor, cystatin C (show CST3 Proteins), in the CSF (show CSF2 Proteins) might contribute in the process of metastasis and spread of the cancer cells in the leptomeningeal tissues

Mouse (Murine) Cathepsin H (CTSH) interaction partners

  1. The data provide strong evidence that CTSH is an important regulator of beta-cell function during progression of T1D

  2. Cathepsin H knockout mice show reduced brain levels of (Met)enkephalin and galanin (show GAL Proteins).

  3. cathepsin H is involved in the SP-B production.

  4. CTSH overexpression in a subset hepatoma may be thyroid hormone receptor (show THRA Proteins) dependent and suggests that this overexpression has an important role in hepatoma progression.

  5. In two mouse models of pancreatic islet cancer, deletion of CtsH reduced tumor progression; mechanisms involved impaired angiogenic switching from premalignant state, poor vascularization of tumors, and increased apoptosis.

  6. In proteolipid protein transgenic mice cathepsin H is upregulated primarily in microglia/macrophages of white matter.

  7. Presence of cathepsin H and (bone morphogenetic protein 4)BMP4 (show BMP4 Proteins) in lung or other developing organs suggest that cathepsin H regulates BMP4 (show BMP4 Proteins) proteolysis in morphogenesis.

Cathepsin H (CTSH) Protein Profile

Protein Summary

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.

Gene names and symbols associated with Cathepsin H Proteins (CTSH)

  • cathepsin H (ctsh)
  • cathepsin H (CTSH)
  • cathepsin H (LOC100101597)
  • cathepsin H (Ctsh)
  • ACC-4 protein
  • ACC-5 protein
  • AL022844 protein
  • CPSB protein
  • CTSH protein
  • fc44c02 protein
  • minichain protein
  • wu:fc44c02 protein
  • zgc:85774 protein

Protein level used designations for Cathepsin H Proteins (CTSH)

cathepsin H , cathepsin H-like , N-benzoylarginine-beta-naphthylamide hydrolase , aleurain , cathepsin B3 , cathepsin BA , pro-cathepsin H , Cat H

GENE ID SPECIES
324818 Danio rerio
496748 Xenopus (Silurana) tropicalis
711437 Macaca mulatta
740462 Pan troglodytes
770109 Gallus gallus
100036949 Xenopus laevis
100101597 Oryctolagus cuniculus
100413104 Callithrix jacchus
100584322 Nomascus leucogenys
1512 Homo sapiens
13036 Mus musculus
25425 Rattus norvegicus
479065 Canis lupus familiaris
396969 Sus scrofa
510524 Bos taurus
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