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Cation Channel, Sperm Associated 3 Proteins (CATSPER3)

Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Additionally we are shipping Cation Channel, Sperm Associated 3 Antibodies (17) and Cation Channel, Sperm Associated 3 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CATSPER3 347732 Q86XQ3
CATSPER3 76856 Q80W99
Rat CATSPER3 CATSPER3 290989  
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Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CATSPER3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Cation Channel, Sperm Associated 3 (CATSPER3) Interaction Partners

Human Cation Channel, Sperm Associated 3 (CATSPER3) interaction partners

  1. Catsper3 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer.

  2. PMID: 12646162 concludes Alu repeats interfere with splicing of DCOHM (show PCBD2 Proteins) and CAVL such that transcripts containing exons of both genes exist.

Mouse (Murine) Cation Channel, Sperm Associated 3 (CATSPER3) interaction partners

  1. Hydrogen peroxide induced upregulation of catsper3 in brain.

  2. Catsper3 has a single channel-forming domain, a pore-loop with the consensus sequence TxDxW, & a coiled-coil protein-protein interaction domain in the C-terminal tail. CatSpers 1,2,3 & 4 may interact directly or indirectly to form a functional tetramer.

  3. CATSPER3 is a cation-channel (show TRPV1 Proteins) protein and has role in acrosome reaction and male fertility

  4. Catsper3 and Catsper4 (show CATSPER4 Proteins) knockout male mice are completely infertile due to a quick loss of motility and a lack of hyperactivated motility under capacitating conditions.

Cation Channel, Sperm Associated 3 (CATSPER3) Protein Profile

Protein Summary

Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation. Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Activated by intracellular alkalinization. Contrary to the human ortholog, not activated by progesterone.

Gene names and symbols associated with CATSPER3

  • cation channel, sperm associated 3 (CATSPER3)
  • cation channel, sperm associated 3 (Catsper3)
  • 4921522D01Rik protein
  • CACRC protein
  • CATSPER3 protein

Protein level used designations for CATSPER3

cation channel, sperm associated 3 , cation channel sperm-associated protein 3 , cation channel sperm-associated protein 3-like , ca(v)-like protein , calcium channel repeat containing 1 , one-repeat calcium channel-like protein , putative ion channel CatSper3

GENE ID SPECIES
471637 Pan troglodytes
481512 Canis lupus familiaris
540820 Bos taurus
100340055 Oryctolagus cuniculus
100435751 Pongo abelii
347732 Homo sapiens
76856 Mus musculus
290989 Rattus norvegicus
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