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Cdk5 and Abl Enzyme Substrate 1 (CABLES1) ELISA Kits

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. Additionally we are shipping Cdk5 and Abl Enzyme Substrate 1 Antibodies (23) and Cdk5 and Abl Enzyme Substrate 1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CABLES1 91768 Q8TDN4
CABLES1 63955 Q9ESJ1
Anti-Rat CABLES1 CABLES1 307585  
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Top Cdk5 and Abl Enzyme Substrate 1 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for Cdk5 and Abl Enzyme Substrate 1 Interaction Partners

Zebrafish Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. cables1 is important for neural differentiation during embryogenesis, in a mechanism that likely involves interactions with the Cdk5 (show CDK5 ELISA Kits)/p35 (show CDK5R1 ELISA Kits) kinase pathway.

Human Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. CABLES1 is a critical regulator of corticotrope proliferation that defines a pathway often inactivated in Cushing disease

  2. the results suggest Cables1 as a novel p21 (show CDKN1A ELISA Kits) regulator through maintaining p21 (show CDKN1A ELISA Kits) stability and support the model that the tumor-suppressive function of Cables1 occurs at least in part through enhancing the tumor-suppressive activity of p21 (show CDKN1A ELISA Kits).

  3. Results illuminated a dynamic regulatory system through which activated Akt (show AKT1 ELISA Kits) and 14-3-3 (show YWHAQ ELISA Kits) work directly together to neutralize a potent tumor suppressor function of Cables1.

  4. The results did not detect a significant association. It indicated that common genetic variations in CDK5 (show CDK5 ELISA Kits) genes might not play a role in the genetic predisposition to autism.

  5. Analysis of the RT-PCR prducts of the CABLES1 gene showed eight intragenic deletions in its mRNA transcripts; 5/8 are the result of RNA splicing.

  6. Mechanisms of CABLES1 gene inactivation in ovarian cancer development are reported.

Mouse (Murine) Cdk5 and Abl Enzyme Substrate 1 (CABLES1) interaction partners

  1. Loss of Cables1 enhances tumor progression in the Apc (show APC ELISA Kits)(Min/+) mouse model and activates the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.

  2. Agenesis of the corpus callosum frequency in Cables1(+/TAS (show MAP3K4 ELISA Kits)) mice was significantly lower than that in Cables1(-/TAS (show MAP3K4 ELISA Kits)) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS (show MAP3K4 ELISA Kits)).

  3. Data show that oocytes lacking Cables1 exhibit lower basal levels of TAp63alpha and reduced accumulation of phosphorylated TAp63alpha in response to genotoxic stress.

  4. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood.

Cdk5 and Abl Enzyme Substrate 1 (CABLES1) Antigen Profile

Antigen Summary

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CABLES1

  • Cdk5 and Abl enzyme substrate 1 (CABLES1) antibody
  • Cdk5 and Abl enzyme substrate 1 (cables1) antibody
  • Cdk5 and Abl enzyme substrate 1 (CpipJ_CPIJ019832) antibody
  • CDK5 and Abl enzyme substrate 1 (Cables1) antibody
  • Cdk5 and Abl enzyme substrate 1 (Cables1) antibody
  • CABL1 antibody
  • Cables antibody
  • CABLES1 antibody
  • HsT2563 antibody
  • ik3-1 antibody
  • si:dkey-2p18.3 antibody

Protein level used designations for CABLES1

Cdk5 and Abl enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1 , CDK5 and ABL1 enzyme substrate 1-like , interactor with CDK3 1 , cdk3-binding protein ik3-1 , interactor-1 with cdk3

GENE ID SPECIES
455335 Pan troglodytes
100059359 Equus caballus
100126070 Danio rerio
100345850 Oryctolagus cuniculus
100479459 Ailuropoda melanoleuca
6054063 Culex quinquefasciatus
100562423 Anolis carolinensis
100603520 Nomascus leucogenys
91768 Homo sapiens
63955 Mus musculus
768914 Gallus gallus
100682687 Canis lupus familiaris
100526114 Sus scrofa
100138286 Bos taurus
307585 Rattus norvegicus
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