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Cell Division Cycle 20 Homolog (S. Cerevisiae) Proteins (CDC20)

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. Additionally we are shipping CDC20 Antibodies (82) and CDC20 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDC20 991 Q12834
CDC20 107995 Q9JJ66
Rat CDC20 CDC20 64515 Q62623
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Top CDC20 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,415.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CDC20 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) Interaction Partners

Human Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Results show that CYP1B1 (show CYP1B1 Proteins) may promote renal cell carcinoma (show MOK Proteins) development by inducing CDC20 expression and inhibiting apoptosis through the down-regulation of DAPK1 (show DAPK1 Proteins).

  2. Study describes a positive feedback loop centred on cyclin A2 (show CCNA2 Proteins)-Cdk2 (show CDK2 Proteins) inhibition of interphase APC (show APC Proteins)/C-Cdc20 to allow further cyclin A2 (show CCNA2 Proteins) accumulation and mitotic entry.

  3. Bub1 (show BUB1 Proteins)-Plk1-mediated phosphorylation of Cdc20 constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (show BUB3 Proteins) complex formation.

  4. The presence of this segment correlates with SAC (show ADCY10 Proteins) activity and efficient binding of CDC20 but not of MAD1 (show MXD1 Proteins) to kinetochores.

  5. These results suggest CDC20 is a critical regulator of TIC (show ARNTL Proteins) proliferation and survival, linking two key TIC (show ARNTL Proteins) nodes-FOXM1 (show FOXM1 Proteins) and p21CIP1/WAF1 (show CDKN1A Proteins)-elucidating a potential point for therapeutic intervention.

  6. CDC20 is essential for the in vivo tumorigenicity of glioblastoma stem-like cells. CDC20 is prognostic of overall survival in Proneural subtype glioblastoma patients.

  7. BUB1B (show BUB1B Proteins) expression was highly correlated to CDC20 and CCNB1 (show CCNB1 Proteins) expression in multiple myeloma cells, leading to increased cell proliferation.

  8. spindle checkpoint release further increases APC (show APC Proteins)/C(Cdc20) catalytic activity

  9. a Cdc20 binding site in BubR1 (show BUB1B Proteins) facilitates both spindle assembly checkpoint signalling and silencing

  10. CDC20, MAD2 (show MAD2L1 Proteins) and Aurora-B (show AURKB Proteins) protein (show LEPREL2 Proteins) expression are associated with chromosomal abnormalities and poor prognosis in patients with myelodysplastic syndromes.

Xenopus laevis Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 auto-ubiquitylation does not play a major role in terminating Cdc20 activation.

  2. Dephosphorylation of Cdc20 is required for its loading and activation of the APC/C ubiquitin ligase.

  3. A role for the fizzy/cdc20 family of proteins in activation of the APC (show APC Proteins)/C distinct from substrate recruitment is reported.

Mouse (Murine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.

  2. The physiologically effective threshold level of Cdc20 is high for female meiosis I.

  3. Results indicate that Cdc20 also contributes to post-anaphase activation of the APC (show APC Proteins)/C.

  4. The seven tandem WD motifs of Cdc20 they are required for speriolin binding and for localization of Cdc20 to the centrosomes and nucleus, suggesting that speriolin might regulate or stabilize the folding of Cdc20 during meiosis in spermatogenic cells

  5. Data suggest that Mad2 (show MXI1 Proteins) and BubR1 (show BUB1B Proteins) must cooperate to inhibit Cdc20 activity.

  6. Cdc20 is degraded through two independent degradation signals (degrons), the KEN box and a newly described CRY (show CRY2 Proteins) box.

  7. Cdc20 and securin (show PTTG1 Proteins) double mutant embryos could not maintain the metaphase arrest, suggesting a role of securin (show PTTG1 Proteins) in preventing mitotic exit

  8. Expression of the cdc20 gene is down-regulated by zif268 (show EGR1 Proteins) in neuronal cells; altered expression of proteasome-regulatory genes following zif268 (show EGR1 Proteins) induction may be a key component of long-lasting CNS plasticity.

  9. Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes

  10. findings suggest a novel function of HSF1 (show HSF1 Proteins) frequently overexpressed in cancer cells, to inhibit APC (show APC Proteins)/C activity by interacting with Cdc20, and to result in aneuploidy development and genomic instability

Pig (Porcine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. porcine FZR1 (show FZR1 Proteins) and CDC20 work on the maintenance of meiotic arrest at the first meiotic prophase and on the exit from M1

CDC20 Protein Profile

Protein Summary

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.

Gene names and symbols associated with CDC20

  • cell division cycle 20 (cdc20)
  • cell division cycle 20 (CDC20)
  • cell division cycle 20 (Cdc20)
  • cell division cycle 20 homolog (S. cerevisiae) (CDC20)
  • 2310042N09Rik protein
  • bA276H19.3 protein
  • C87100 protein
  • CDC20A protein
  • fizzy1 protein
  • p55CDC protein
  • X-FZY protein

Protein level used designations for CDC20

cell division cycle 20 homolog , CDC20 cell division cycle 20 homolog , cell division cycle protein 20 homolog , fizzy1 , mmCdc20 , cell cycle protein p55CDC , p55CDC

GENE ID SPECIES
394542 Xenopus (Silurana) tropicalis
991 Homo sapiens
398044 Xenopus laevis
107995 Mus musculus
64515 Rattus norvegicus
424563 Gallus gallus
482534 Canis lupus familiaris
397379 Sus scrofa
515376 Bos taurus
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