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anti-Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) Antibodies

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. Additionally we are shipping CDC20 Proteins (6) and CDC20 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDC20 991 Q12834
CDC20 107995 Q9JJ66
CDC20 64515 Q62623
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Top anti-CDC20 Antibodies at antibodies-online.com

Showing 10 out of 211 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/HeLa cells, using p55CDC Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Log in to see 6 to 8 Days
$419.10
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP Western Blot: CDC20 Antibody [ABIN252980] - Detection of Human CDC20 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CDC20 antibody ABIN252980 used for IP at 3 mcg/mg lysate. CDC20 was also immunoprecipitated by rabbit anti- CDC20 antibody ABIN252981, which recognizes a downstream epitope. Immunohistochemistry-Paraffin: Cdc20 Antibody [ABIN2529807] - Detection of Mouse CDC20 by Immunohistochemistry. FFPE section of mouse teratoma. Affinity purified rabbit anti-CDC20 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a 100 μL Log in to see 2 to 3 Days
$379.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, PLA, WB Western Blot and Immunoprecipitation: CDC20 Antibody [ABIN252981] - Detection of Human CDC20 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CDC20 antibody ABIN252981 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CDC20 was also immunoprecipitated by rabbit anti-CDC20 antibody ABIN252980, which recognizes an upstream epitope. Immunohistochemistry-Paraffin: Cdc20 Antibody [ABIN2529818] - FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-CDC20 used at a dilution of 1:250. 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Rat Rabbit Un-conjugated WB Anti-Cdc20 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: Rat Spleen Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CDC20 Antibody (N-term) (ABIN653082) in Hela cell line lysates (35 µg/lane). CDC20 (arrow) was detected using the purified polyclonal antibody. CDC20 Antibody (N-term) (ABIN653082) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Cdc20 Polyclonal Antibody. 100 μL Log in to see 14 Days
$175.80
Details

CDC20 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) , ,


Rat (Rattus)


Top referenced anti-CDC20 Antibodies

  1. Human Polyclonal CDC20 Primary Antibody for EIA, IP - ABIN117946 : Jentsch, Pyrowolakis: Ubiquitin and its kin: how close are the family ties? in Trends in cell biology 2000 (PubMed)
    Show all 8 references for ABIN117946

  2. Human Polyclonal CDC20 Primary Antibody for ICC, IF - ABIN252981 : Di Fiore, Pines: How cyclin A destruction escapes the spindle assembly checkpoint. in The Journal of cell biology 2010 (PubMed)
    Show all 3 references for ABIN252981

  3. Human Polyclonal CDC20 Primary Antibody for ICC, IF - ABIN252980 : Ahlskog, Björk, Elsing, Aspelin, Kallio, Roos-Mattjus, Sistonen: Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress. in Molecular and cellular biology 2010 (PubMed)
    Show all 2 references for ABIN252980

  4. Cow (Bovine) Polyclonal CDC20 Primary Antibody for IHC, WB - ABIN2774602 : Wolthuis, Clay-Farrace, van Zon, Yekezare, Koop, Ogink, Medema, Pines: Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. in Molecular cell 2008 (PubMed)

  5. Human Polyclonal CDC20 Primary Antibody for IP, WB - ABIN233786 : Yamamuro, Kano, Naito: Functions of FZR1 and CDC20, activators of the anaphase-promoting complex, during meiotic maturation of swine oocytes. in Biology of reproduction 2008 (PubMed)

  6. Human Polyclonal CDC20 Primary Antibody for ELISA, WB - ABIN1534317 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

More Antibodies against CDC20 Interaction Partners

Human Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. These results provide novel insight into the mechanisms underlying the aberrant capability of NUP98 (show NUP98 Antibodies) oncoproteins to interact with APC (show APC Antibodies)/C(Cdc20) and to interfere with its function.

  2. In lung adenocarcinoma patients, overexpression of cell division cycle 20 was significantly associated with bigger primary tumor size, higher MKI67 (show MKI67 Antibodies) level, higher DNA ploidy level, and poor prognosis.

  3. CDC20 may have a role in carcinoma of the breast, colon, endometrium, and prostate

  4. Overexpression of Cdc20 may serve as an independent predictor for biochemical recurrence in patients of clinically localized prostate cancer undergoing laparoscopic radical prostatectomy without neoadjuvant therapy.

  5. Results show that CYP1B1 (show CYP1B1 Antibodies) may promote renal cell carcinoma (show MOK Antibodies) development by inducing CDC20 expression and inhibiting apoptosis through the down-regulation of DAPK1 (show DAPK1 Antibodies).

  6. Study describes a positive feedback loop centred on cyclin A2 (show CCNA2 Antibodies)-Cdk2 (show CDK2 Antibodies) inhibition of interphase APC (show APC Antibodies)/C-Cdc20 to allow further cyclin A2 (show CCNA2 Antibodies) accumulation and mitotic entry.

  7. Bub1 (show BUB1 Antibodies)-Plk1 (show PLK1 Antibodies)-mediated phosphorylation of Cdc20 constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (show BUB3 Antibodies) complex formation.

  8. The presence of this segment correlates with SAC (show ADCY10 Antibodies) activity and efficient binding of CDC20 but not of MAD1 (show MXD1 Antibodies) to kinetochores.

  9. These results suggest CDC20 is a critical regulator of TIC (show ARNTL Antibodies) proliferation and survival, linking two key TIC (show ARNTL Antibodies) nodes-FOXM1 (show FOXM1 Antibodies) and p21CIP1/WAF1 (show CDKN1A Antibodies)-elucidating a potential point for therapeutic intervention.

  10. CDC20 is essential for the in vivo tumorigenicity of glioblastoma stem-like cells. CDC20 is prognostic of overall survival in Proneural subtype glioblastoma patients.

Xenopus laevis Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 auto-ubiquitylation does not play a major role in terminating Cdc20 activation.

  2. Dephosphorylation of Cdc20 is required for its loading and activation of the APC/C ubiquitin ligase.

  3. A role for the fizzy/cdc20 family of proteins in activation of the APC (show APC Antibodies)/C distinct from substrate recruitment is reported.

Mouse (Murine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. Cdc20 hypomorphism causes chromatin bridging and chromosome misalignment, revealing a requirement for Cdc20 in efficient sister chromosome separation and chromosome-microtubule attachment.

  2. The physiologically effective threshold level of Cdc20 is high for female meiosis I.

  3. Results indicate that Cdc20 also contributes to post-anaphase activation of the APC (show APC Antibodies)/C.

  4. The seven tandem WD motifs of Cdc20 they are required for speriolin binding and for localization of Cdc20 to the centrosomes and nucleus, suggesting that speriolin might regulate or stabilize the folding of Cdc20 during meiosis in spermatogenic cells

  5. Data suggest that Mad2 (show MXI1 Antibodies) and BubR1 (show BUB1B Antibodies) must cooperate to inhibit Cdc20 activity.

  6. Cdc20 is degraded through two independent degradation signals (degrons), the KEN (show PCNT Antibodies) box and a newly described CRY (show CRY2 Antibodies) box.

  7. Cdc20 and securin (show PTTG1 Antibodies) double mutant embryos could not maintain the metaphase arrest, suggesting a role of securin (show PTTG1 Antibodies) in preventing mitotic exit

  8. Expression of the cdc20 gene is down-regulated by zif268 (show EGR1 Antibodies) in neuronal cells; altered expression of proteasome-regulatory genes following zif268 (show EGR1 Antibodies) induction may be a key component of long-lasting CNS plasticity.

  9. Cdc20 is required for the anaphase onset of the first meiosis but not the second meiosis in mouse oocytes

  10. findings suggest a novel function of HSF1 (show HSF1 Antibodies) frequently overexpressed in cancer cells, to inhibit APC (show APC Antibodies)/C activity by interacting with Cdc20, and to result in aneuploidy development and genomic instability

Pig (Porcine) Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20) interaction partners

  1. porcine FZR1 (show FZR1 Antibodies) and CDC20 work on the maintenance of meiotic arrest at the first meiotic prophase and on the exit from M1

CDC20 Antigen Profile

Protein Summary

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.

Gene names and symbols associated with CDC20

  • cell division cycle 20 (cdc20) antibody
  • cell division cycle 20 (CDC20) antibody
  • cell division cycle 20 (Cdc20) antibody
  • cell division cycle 20 homolog (S. cerevisiae) (CDC20) antibody
  • 2310042N09Rik antibody
  • bA276H19.3 antibody
  • C87100 antibody
  • CDC20A antibody
  • fizzy1 antibody
  • p55CDC antibody
  • X-FZY antibody

Protein level used designations for CDC20

cell division cycle 20 homolog , CDC20 cell division cycle 20 homolog , cell division cycle protein 20 homolog , fizzy1 , mmCdc20 , cell cycle protein p55CDC , p55CDC

GENE ID SPECIES
394542 Xenopus (Silurana) tropicalis
991 Homo sapiens
398044 Xenopus laevis
107995 Mus musculus
64515 Rattus norvegicus
424563 Gallus gallus
482534 Canis lupus familiaris
397379 Sus scrofa
515376 Bos taurus
Selected quality suppliers for anti-CDC20 (CDC20) Antibodies
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