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Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) ELISA Kit Abstract

CDC25A is a member of the CDC25 family of phosphatases. antibodies-online currently ships Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) Antibodies (370), and to destinations worldwide.

list all ELISA KIts Gene Name GeneID UniProt
CDC25A 993 P30304
CDC25A 171102 P48965
CDC25A 12530  

Show Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) Antigene Profile

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Showing 9 out of 13 Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) ELISA Kits

ABIN Reactivity Sensitivity Range Quantity Delivery Validation Price Details
ABIN812241 Human n/a n/a 96 Tests 11 to 13 Days Data Validation Level 4/5
910.56 $
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ABIN812243 Rat n/a n/a 96 Tests 11 to 13 Days Data Validation Level 4/5
910.56 $
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ABIN826321 Cow n/a n/a 96 Tests 11 to 13 Days Data Validation Level 4/5
1,026.67 $
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ABIN812242 Mouse n/a n/a 96 Tests 11 to 13 Days Data Validation Level 4/5
910.56 $
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ABIN1380385 Human n/a n/a 96 Tests 21 to 31 Days Data Validation Level 3/5
450.00 $
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ABIN1380539 Human n/a n/a 96 Tests 21 to 31 Days Data Validation Level 3/5
450.00 $
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ABIN1380738 Human n/a n/a 96 Tests 21 to 31 Days Data Validation Level 3/5
450.00 $
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ABIN1381006 Human n/a n/a 96 Tests 21 to 31 Days Data Validation Level 3/5
350.00 $
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ABIN1380143 n/a n/a 96 Tests 2 to 3 Days Data Validation Level 1/5
450.00 $
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More ELISA Kits for Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) Interaction Partners

Human Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. accelerated cholangiocyte cystogenesis is likely due to overexpression of Cdc25A

  2. CDC 25A dephosphorylates NFAT (show NFATC1 ELISA Kits), resulting in translocation to nucleus and NFAT (show NFATC1 ELISA Kits) in co-operation with Smad2 (show SMAD2 ELISA Kits) promotes the tumor progression.

  3. RSK (show RPS6KA1 ELISA Kits) promotes G2/M transition in mammalian cells through activating phosphorylation of Cdc25A and Cdc25B (show CDC25B ELISA Kits)

  4. Triptolide induces S phase arrest via the promotion of p21 (show CDKN1A ELISA Kits) and p27 and the inhibition of cyclin A (show CCNA2 ELISA Kits) and CDC25A expression.

  5. Overexpression of CDC25A was associated with the decrease of overall survival rates and disease-free survival in breast cancer patients.CDC25a is a target of HER2 (show ERBB2 ELISA Kits) signaling in human breast cancer.

  6. Overexpression of EGFR (show EGFR ELISA Kits) in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes.

  7. Data indicate that protein phosphatase inhibitor RE142 binds to one of the residues Cys384-Tyr386 of CDC25A, within a pocket adjacent to the catalytic site.

  8. Our work provides novel insight into the underlying mechanisms by which FOXM1 controls the cell cycle through its association with CDC25A.

  9. Studies indicate that the ATR (show ATR ELISA Kits)-Chk1 (show CHEK1 ELISA Kits)-Cdc25 (show CDC25C ELISA Kits) pathway is the sole checkpoint route in a majority of cancer cells.

  10. destabilization of Cdc25A through inhibition of Hsp90 was boosted by the phosphorylation of Ser177 which tags Cdc25A to proteasomal degradation and this added up to the cell-cycle inhibitory effect

Mouse (Murine) Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. accelerated cholangiocyte cystogenesis is likely due to overexpression of Cdc25A

  2. Cdc25A activity is required for the metaphase II arrest in mouse oocytes.

  3. deletion of Cdc25a increased apoptosis and accelerated the elimination of DNA damage following UV

  4. In the DNA damage response, instead of inhibiting cyclin B (show CCNB1 ELISA Kits)-CDK1 (show CDK1 ELISA Kits) through destruction of Cdc25A phosphatase, oocytes utilize an inhibitory phosphorylation of Cdc25B (show CDC25B ELISA Kits).

  5. Cdc25A inhibitors block cell-cycle progression and proliferation, reduce liver and kidney weights and cyst growth in animal models of polycystic kidney/liver disease.

  6. CDC25A and CDC25B (show CDC25B ELISA Kits) but not CDC25C (show CDC25C ELISA Kits) compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells

  7. IL-7 (show IL7 ELISA Kits) drives Cdc25A-mediated T-cell proliferation, which prevents the nuclear translocation of Foxo1 (show FOXO1 ELISA Kits), leading to reduced expression of CD62L (show SELL ELISA Kits) and the migration of T cells into circulation.

  8. Results reveal an unexpected role of Cdc25A down-regulation and the inhibitory phosphorylation of cdk2 (show CDK2 ELISA Kits) T14 (show CD27 ELISA Kits) and Y15 in cell cycle quiescence during muscle differentiation and implicate miRNAs-322 and -503 in the process.

  9. Cdc25A degradation does not inhibit Cdk2 (show CDK2 ELISA Kits) activity because a considerable proportion of Cdk2 (show CDK2 ELISA Kits) molecules localize to the cytoplasm and centrosomes in mESCs, where they may be sheltered from regulation by nuclear Cdc25A.

  10. human papillomavirus type 16 E7 maintains elevated levels of the cdc25A tyrosine phosphatase during deregulation of cell cycle arrest

Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) Antigen Profile

Gene names and symbols associated with CDC25A

cell division cycle 25 homolog A (S. pombe) (CDC25A) , cell division cycle 25A (cdc25a) , cell division cycle 25 homolog (cdc25) , cell division cycle 25A (CDC25A) , cell division cycle 25A (Cdc25a)

cdc25a2 , cdc25A , sb:cb317 , CDC25A2 , D9Ertd393e

Protein level used designations for CDC25A

cell division cycle 25A , cell division cycle 25 homolog A , M-phase inducer phosphatase 1 , Dual specificity phosphatase Cdc25A , CDC25A2-CAG isoform , dual specificity phosphatase CDC25A , dual specificity phosphatase Cdc25A

Antigen Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

GENE ID SPECIES
460341 Pan troglodytes
733851 Xenopus (Silurana) tropicalis
57925 Danio rerio
420375 Gallus gallus
484780 Canis lupus familiaris
520188 Bos taurus
100064223 Equus caballus
993 Homo sapiens
171102 Rattus norvegicus
12530 Mus musculus
734734 Xenopus laevis
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