CDC25A Products
(Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
Categories
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured CDC25A Categories
CDC25A Antibodies
High quality antibodies with extensive validation data.
CDC25A ELISA Kits
Reliable ELISA kits for a wide range of species.
CDC25A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CDC25A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (6)
Cat. No.
ABIN389527
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3021626
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6255495
Quantity
100 μL
Datasheet
Datasheet
Recommended CDC25A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380539
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380385
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380738
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended CDC25A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348790
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348792
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6386706
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CDC25A products
: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).: "Silencing CDC25A inhibits the proliferation of liver cancer cells by downregulating IL‑6 in vitro and in vivo." in: International journal of molecular medicine, Vol. 45, Issue 3, pp. 743-752, (2020) (PubMed).
: "Regulation of Signaling Pathways Involved in the Anti-proliferative and Apoptosis-inducing Effects of M22 against Non-small Cell Lung Adenocarcinoma A549 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 992, (2018) (PubMed).
: "Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways." in: The Science of the total environment, Vol. 589, pp. 97-106, (2017) (PubMed).
: "A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in ..." in: Mutation research, Vol. 777, pp. 79-90, (2015) (PubMed).
: "Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
: "A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk." in: Oncogene, (2015) (PubMed).
: "Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 5, pp. 761-71, (2015) (PubMed).
: "CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute." in: Oncogene, Vol. 31, Issue 4, pp. 403-18, (2012) (PubMed).
: "An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis." in: International journal of oncology, Vol. 40, Issue 6, pp. 2131-9, (2012) (PubMed).
Synonyms and alternative names related to CDC25A
cell division cycle 25A (CDC25A), cell division cycle 25A (cdc25a), cell division cycle 25B (cdc25b), cell division cycle 25A (Cdc25a), cell division cycle 25A S homeolog (cdc25a.S), cdc25A, cdc25a2, CDC25A2, D9Ertd393e, sb:cb317Protein level used designations for CDC25A
- cell division cycle 25A
- cell division cycle 25 homolog A
- M-phase inducer phosphatase 1
- Dual specificity phosphatase Cdc25A
- CDC25A2-CAG isoform
- dual specificity phosphatase CDC25A
- dual specificity phosphatase Cdc25A
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