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Cell Division Cycle Associated 5 Proteins (CDCA5)

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. Additionally we are shipping Cell Division Cycle Associated 5 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CDCA5 CDCA5 499310  
CDCA5 113130 Q96FF9
CDCA5 67849 Q9CPY3
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Top Cell Division Cycle Associated 5 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,700.50
Details

CDCA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cell Division Cycle Associated 5 (CDCA5) Interaction Partners

Human Cell Division Cycle Associated 5 (CDCA5) interaction partners

  1. the C-terminus of Sororin functions as an anchor binding to SA2 (show STAG2 Proteins), which facilitates other conserved motifs on Sororin to interact with other proteins to regulate sister chromatid cohesion and separation.

  2. We propose that the Prp19 (show PRPF19 Proteins) complex and the splicing machinery contribute to the establishment of cohesion by promoting Sororin accumulation during S phase, and are, therefore, essential to the maintenance of genome stability.

  3. A transcriptome-wide analysis revealed that SNW1 (show SNW1 Proteins) or PRPF8 depletion affects the splicing of specific introns in a subset of pre-mRNAs, including pre-mRNAs encoding the cohesion protein sororin and the APC (show APC Proteins)/C subunit APC2.

  4. Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia.

  5. Data show that the MEK (show MAP2K1 Proteins)-ERK (show EPHB2 Proteins) pathway regulates cell cycle-related neuronal apoptosis (CRNA) by elevating the levels of cyclin D1 (show CCND1 Proteins), and the increase in cyclin D1 (show CCND1 Proteins) attenuates the activation of cyclin-dependent kinase 5 (cdk5 (show CDK5 Proteins)) by its neuronal activator p35 (show ANXA1 Proteins).

  6. Sororin is phosphorylated by Cdk1/cyclin B at prophase and acts as a docking protein to bring Plk1 into proximity with SA2, resulting in the phosphorylation of SA2 and the removal of cohesin complexes from chromosomal arms.

  7. the interaction of the highly conserved motif at the C terminus of sororin with the cohesin complex (show SMC3 Proteins) is critical to its ability to mediate sister chromatid cohesion.

  8. Transactivation of CDCA5 and its phosphorylation at Ser209 by ERK (show EPHB2 Proteins) play an important role in lung cancer proliferation.

  9. data indicate that sororin interacts with chromatin-bound cohesin and functions during the establishment or maintenance of cohesion in S or G2 phase, respectively

  10. Sororin protects centromeric cohesion in response to the spindle checkpoint, but prevents the removal of cohesion by a mechanism independent of the anaphase-promoting complex.

Mouse (Murine) Cell Division Cycle Associated 5 (CDCA5) interaction partners

  1. The authors show that sororin is essential for embryonic development, cohesion maintenance, and proper chromosome segregation.

Cell Division Cycle Associated 5 (CDCA5) Protein Profile

Protein Summary

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of wapal which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair (Probable).

Gene names and symbols associated with CDCA5

  • cell division cycle associated 5 (CDCA5)
  • cell division cycle associated 5 (Cdca5)
  • cell division cycle associated 5 (cdca5)
  • cell division cycle associated 5 (cdca5-a)
  • 2610036L13Rik protein
  • AL024086 protein
  • AW536684 protein
  • C85404 protein
  • cdca5 protein
  • RGD1560863 protein
  • SORORIN protein

Protein level used designations for CDCA5

cell division cycle associated 5 , cell division cycle-associated protein 5 , p35 , sororin , sororin p35 , cell division cycle-associated protein 5-A , xp35

GENE ID SPECIES
451310 Pan troglodytes
499310 Rattus norvegicus
100145078 Xenopus (Silurana) tropicalis
113130 Homo sapiens
67849 Mus musculus
612071 Canis lupus familiaris
613318 Bos taurus
684771 Rattus norvegicus
733230 Xenopus laevis
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