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Cellular Repressor of E1A-Stimulated Genes 1 Proteins (CREG1)

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Additionally we are shipping CREG1 Antibodies (90) and CREG1 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CREG1 8804 O75629
CREG1 433375 O88668
Rat CREG1 CREG1 289185  
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Top CREG1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Mouse His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Mouse His tag   10 μg Log in to see 5 Days
$154.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.1 mg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CREG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) , ,
,

Top referenced CREG1 Proteins

  1. Human CREG1 Protein expressed in Escherichia coli (E. coli) - ABIN1098379 : Han, Luan, Sun, Guo, Guo, Tao, Deng, Wu, Liu, Yan, Li et al.: Glycosylation-independent binding to extracellular domains 11-13 of mannose-6-phosphate/insulin-like growth factor-2 receptor mediates the effects of soluble CREG on the phenotypic modulation of ... in Journal of molecular and cellular cardiology 2011 (PubMed)
    Show all 2 references for ABIN1098379

More Proteins for Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) Interaction Partners

Human Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) interaction partners

  1. These results indicate that CREG1 is a down-stream effector of KRAS in a sub-type of non-small cell lung cancer cells and a novel candidate biomarker or therapeutic target for KRAS mutant non-small cell lung cancer.

  2. Results indicate that cellular repressor of E1A (show BCKDHA Proteins)-stimulated gene 1 protein (CREG1) increases endothelial cell (EC) filopodia formation.

  3. The results suggest a novel role of CREG to promote HUVEC proliferation through the ERK (show EPHB2 Proteins)/cyclin E (show CCNE1 Proteins) signaling pathway.

  4. CREG can inhibit NF-kappaB (show NFKB1 Proteins) activation, TNF-alpha (show TNF Proteins)-induced inflammatory responses and the hyperpermeability of endothelial cells.

  5. miR (show MLXIP Proteins)-31 not only directly binds to its target gene CREG and modulates the vascular smooth muscle cells(VSMC) phenotype through this interaction, but also can be an important biomarker in diseases involving VSMC phenotypic modulation.

  6. Suggest that CREG is a novel adventitial fibroblast phenotypic modulator in a p38MAPK (show MAPK14 Proteins)-dependent manner.

  7. CREG plays a critical role in protecting the vascular endothelium from apoptosis, and the protective effort of CREG against ECs apoptosis is through the activation of the VEGF (show VEGFA Proteins)/PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling pathway

  8. Upregulation of CREG expression induced HUVEC migration.

  9. Cooperation of CREG1 and p16 (INK4a) inhibits the expression of cyclin A (show CCNA2 Proteins) and cyclin B by inhibiting promoter activity thereby decreasing mRNA and protein levels; these proteins are required for S-phase entry and G2/M transition.

  10. Data suggest that soluble CREG protein can exert its biological function via glycosylation-independent binding to the extracellular domains 11-13 of cell surface M6P/IGF2R (show IGF2R Proteins), modulating SMC (show DYM Proteins) phenotypic switching from contractile to proliferative.

Mouse (Murine) Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) interaction partners

  1. CREG inhibits inflammation and promotes autophagy mediated by lysosome formation; it might be a potential therapeutic target in atherosclerosis.

  2. CREG1 deficiency influenced the maturation of lysosomes and reduced the espression of Rab7 (show RAB7A Proteins), which might be involved in CREG1-induced cardiomyocyte autophagy.

  3. Data indicate cellular repressor of E1A (show BCKDHA Proteins)-stimulated gene (CREG) as a factor in regulating endothelial differentiation and vasculogenesis via VEGF (show VEGFA Proteins)/PI3K/Akt (show AKT1 Proteins) pathway.

  4. Suggest that CREG is a novel adventitial fibroblast phenotypic modulator in a p38MAPK (show MAPK14 Proteins)-dependent manner.

  5. CREG plays a critical role in protecting the vascular endothelium from apoptosis, and the protective effort of CREG against ECs apoptosis is through the activation of the VEGF (show VEGFA Proteins)/PI3K/AKT (show AKT1 Proteins) signaling pathway

  6. These results indicate that CREG is expressed during mouse embryogenesis and might participate in the differentiation of these organs during embryogenesis.

  7. Results show that CREG is a lysosomal protein that undergoes proteolytic maturation during biosynthesis, carries the mannose 6-phosphate recognition marker and depends on the interaction with M-6-P receptors for efficient delivery to lysosomes.

  8. Secreted Creg inhibits cell proliferation mediated by mannose-6-phosphate/insulin-like growth factor II receptor (show IGF2R Proteins) in NIH 3T3 fibroblasts.

CREG1 Protein Profile

Protein Summary

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

Gene names and symbols associated with CREG1

  • cellular repressor of E1A-stimulated genes 1 (CREG1)
  • cellular repressor of E1A-stimulated genes 1 (creg1)
  • cellular repressor of E1A-stimulated genes 1 (Creg1)
  • AA755314 protein
  • Creg protein
  • CREG1 protein

Protein level used designations for CREG1

cellular repressor of E1A-stimulated genes 1 , protein CREG1 , Protein CREG1 , hypothetical protein

GENE ID SPECIES
701021 Macaca mulatta
734028 Xenopus (Silurana) tropicalis
747516 Pan troglodytes
8804 Homo sapiens
530908 Bos taurus
433375 Mus musculus
289185 Rattus norvegicus
768680 Gallus gallus
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