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CREG1 Protein (Fc Tag)

CREG1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Catalog No. ABIN7320061
  • Target See all CREG1 Proteins
    CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
    Protein Type
    Recombinant
    Origin
    • 6
    • 5
    Mouse
    Source
    • 4
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CREG1 protein is labelled with Fc Tag.
    Purpose
    Recombinant Mouse CREG/CREG1 Protein (Fc Tag)
    Sequence
    Met1-Gln220
    Characteristics
    A DNA sequence encoding the mouse CREG (O88668)(Met1-Gln220) was expressed with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 90 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product CREG1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
    Alternative Name
    CREG/CREG1 (CREG1 Products)
    Synonyms
    CREG1 Protein, CREG Protein, AA755314 Protein, Creg Protein, cellular repressor of E1A stimulated genes 1 Protein, cellular repressor of E1A-stimulated genes 1 Protein, CREG1 Protein, creg1 Protein, Creg1 Protein
    Background

    Background: CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.

    Synonym: CREG1, cellular repressor of E1A-stimulated genes, cellular repressor of E1A-stimulated genes 1CREG, protein CREG1

    Molecular Weight
    48.5 kDa
    UniProt
    O88668
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