CREG1 Protein (Fc Tag)
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- Target See all CREG1 Proteins
- CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CREG1 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse CREG/CREG1 Protein (Fc Tag)
- Sequence
- Met1-Gln220
- Characteristics
- A DNA sequence encoding the mouse CREG (O88668)(Met1-Gln220) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 90 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CREG1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))
- Alternative Name
- CREG/CREG1 (CREG1 Products)
- Synonyms
- CREG1 Protein, CREG Protein, AA755314 Protein, Creg Protein, cellular repressor of E1A stimulated genes 1 Protein, cellular repressor of E1A-stimulated genes 1 Protein, CREG1 Protein, creg1 Protein, Creg1 Protein
- Background
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Background: CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.
Synonym: CREG1, cellular repressor of E1A-stimulated genes, cellular repressor of E1A-stimulated genes 1CREG, protein CREG1
- Molecular Weight
- 48.5 kDa
- UniProt
- O88668
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