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Centrosomal Protein 63kDa Proteins (CEP63)

CEP63 encodes a protein with six coiled-coil domains. Additionally we are shipping CEP63 Antibodies (31) and CEP63 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CEP63 300963 Q4KLY0
CEP63 28135  
CEP63 80254 Q96MT8
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Top CEP63 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,536.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CEP63 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human
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More Proteins for Centrosomal Protein 63kDa (CEP63) Interaction Partners

Mouse (Murine) Centrosomal Protein 63kDa (CEP63) interaction partners

  1. Cep63-deficient mice recapitulate Seckel syndrome pathology, microcephaly and dwarfism. Cep63 loss severely impairs meiotic recombination, leading to profound male infertility.

  2. both mouse and human Cep63 and Cep152 cooperate to ensure efficient centriole duplication by promoting the accumulation of essential centriole duplication factors upstream of SAS-6 (show SASS6 Proteins) recruitment and procentriole formation.

  3. Cep63 regulates mother-centriole-dependent centriole duplication.

Human Centrosomal Protein 63kDa (CEP63) interaction partners

  1. CEP63 is particularly important for brain development and might control the proliferation and migration of cells when those two events need to be highly coordinated.

  2. centrosomal Cdk1 (show CDK1 Proteins) signals were strongly diminished in cells treated with Cep63 siRNA when sc-54 was used for Cdk1 (show CDK1 Proteins) labeling

  3. both mouse and human Cep63 and Cep152 cooperate to ensure efficient centriole duplication by promoting the accumulation of essential centriole duplication factors upstream of SAS-6 (show SASS6 Proteins) recruitment and procentriole formation.

  4. Cep57, Cep63, and Cep152 are parts of a ring-like complex localizing around the proximal end of centrioles.

  5. One new SNP (rs112926188) in CEP63O was reported. Analysis showed that rs112926188 allele substituting proline at the 61st residue position of CEP63 produced more flexibility in three-deimensional space.

  6. Findings define Cep63 as a centrosomal recruitment factor for Cdk1 (show CDK1 Proteins) that is essential for mitotic entry, providing a physical link between the centrosome and the cell-cycle machinery.

  7. CEP63 transcripts exhibited three different expression patterns, downregulation was found in about 50% of the cases analyzed and CEP63 gene transcription was associated with invasive tumors.

Xenopus laevis Centrosomal Protein 63kDa (CEP63) interaction partners

  1. ATM (show ATM Proteins) and ATR control mitotic events in vertebrate cells by targeting CEP63 and centrosome dependent spindle assembly.

CEP63 Protein Profile

Protein Summary

This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Gene names and symbols associated with CEP63

  • centrosomal protein 63kDa (CEP63)
  • centrosomal protein 63kDa (SYO3AOP1_1060)
  • centrosomal protein 63kDa (Cep63)
  • centrosomal protein 63 (Cep63)
  • centrosomal protein 63 (cep63)
  • centrosomal protein 63kDa (cep63)
  • 4921501M07 protein
  • AL450317.13gm1 protein
  • AW107703 protein
  • CD20R protein
  • Cep63-A protein
  • Cep63-B protein
  • D9Mgc41 protein
  • D9Mgc48e protein
  • ET2 protein
  • Xcep63 protein
  • zgc:63548 protein

Protein level used designations for CEP63

centrosomal protein 63kDa , centrosomal protein 63 , centrosomal protein of 63 kDa-like , centrosomal protein of 63 kDa , centrosome protein Cep63 , centrosome protein CEP63 , Centrosomal protein of 63 kDa-A , Centrosomal protein of 63 kDa-B

GENE ID SPECIES
460713 Pan troglodytes
477075 Canis lupus familiaris
717266 Macaca mulatta
6332695 Sulfurihydrogenibium sp. YO3AOP1
100023216 Monodelphis domestica
100053151 Equus caballus
100597769 Nomascus leucogenys
300963 Rattus norvegicus
28135 Mus musculus
393574 Danio rerio
80254 Homo sapiens
424873 Gallus gallus
496369 Xenopus laevis
100174110 Pongo abelii
100722754 Cavia porcellus
521932 Bos taurus
101114919 Ovis aries
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