CEP63 Protein (AA 1-495, full length) (His-SUMO Tag)
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- Target See all CEP63 Proteins
- CEP63 (Centrosomal Protein 63kDa (CEP63))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-495, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CEP63 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MEALLEGIQN RGHGGGFLTS CEAELQELMK QIDIMVAHKK SEWEGRTHAL ETCLKIREQE LKSLRSQLDV THKEVGMLHQ QVEEHEKIKQ EMTMEYKQEL KKLHEELCIL KRSYEKLQKK QMREFRGNTK NHREDRSEIE RLTAKIEEFR QKSLDWEKQR LIYQQQVSSL EAQRKALAEQ SEIIQAQLVN RKQKLESVEL SSQSEIQHLS SKLERANDTI CANELEIERL TMRVNDLVGT SMTVLQEQQQ KEEKLRESEK LLEALQEEKR ELKAALQSQE NLIHEARIQK EKLQEKVKAT NTQHAVEAIS LESVSATCKQ LSQELMEKYE ELKRMEAHNN EYKAEIKKLK EQILQGEQSY SSALEGMKME ISHLTQELHQ RDITIASTKG SSSDMEKRLR AEMQKAEDKA VEHKEILDQL ESLKLENRHL SEMVMKLELG LHECSLPVSP LGSIATRFLE EEELRSHHIL ERLDAHIEEL KRESEKTVRQ FTALK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CEP63 Protein
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Centrosomal Protein 63kDa (CEP63) (AA 1-703) protein (Strep Tag)
Crystallography grade CEP63 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Centrosomal Protein 63kDa (CEP63) (AA 1-700) protein (Strep Tag)Crystallography grade CEP63 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Centrosomal Protein 63kDa (CEP63) protein (His tag)CEP63 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CEP63 (Centrosomal Protein 63kDa (CEP63))
- Alternative Name
- CEP63 (CEP63 Products)
- Synonyms
- 4921501M07 Protein, AL450317.13gm1 Protein, AW107703 Protein, CD20R Protein, D9Mgc41 Protein, D9Mgc48e Protein, ET2 Protein, zgc:63548 Protein, Cep63-A Protein, Cep63-B Protein, Xcep63 Protein, centrosomal protein 63 Protein, centrosomal protein 63kDa Protein, centrosomal protein 63kDa L homeolog Protein, CEP63 Protein, SYO3AOP1_1060 Protein, Cep63 Protein, cep63 Protein, cep63.L Protein
- Background
- Required for normal spindle assbly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is roved from centrosomes, this leads to the inactivation of spindle assbly and delay in mitotic progression.
- Molecular Weight
- 73.87 kDa
- UniProt
- Q96MT8
- Pathways
- M Phase
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