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Chemokine (C-C Motif) Ligand 28 Proteins (CCL28)

CCL28 belongs to the subfamily of small cytokine CC genes. Additionally we are shipping CCL28 Antibodies (58) and CCL28 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL28 114492  
CCL28 56477 Q9NRJ3
CCL28 56838 Q9JIL2
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Top CCL28 Proteins at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details

CCL28 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human ,
, ,
Mouse (Murine)
,

Top referenced CCL28 Proteins

  1. Human CCL28 Protein expressed in Escherichia coli (E. coli) - ABIN2666749 : Hieshima, Kawasaki, Hanamoto, Nakayama, Nagakubo, Kanamaru, Yoshie: CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 7 references for ABIN2666749

  2. Human CCL28 Protein expressed in Escherichia coli (E. coli) - ABIN2666974 : Eksteen, Miles, Curbishley, Tselepis, Grant, Walker, Adams: Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 7 references for ABIN2666974

  3. Mouse (Murine) CCL28 Protein expressed in Escherichia coli (E. coli) - ABIN2666751 : Facciabene, Peng, Hagemann, Balint, Barchetti, Wang, Gimotty, Gilks, Lal, Zhang, Coukos: Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. in Nature 2011 (PubMed)
    Show all 7 references for ABIN2666751

  4. Mouse (Murine) CCL28 Protein expressed in Escherichia coli (E. coli) - ABIN2666975 : Liu, Wilson: The antimicrobial activity of CCL28 is dependent on C-terminal positively-charged amino acids. in European journal of immunology 2010 (PubMed)
    Show all 7 references for ABIN2666975

  5. Human CCL28 Protein expressed in Escherichia coli (E. coli) - ABIN666664 : Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 2 references for ABIN666664

More Proteins for Chemokine (C-C Motif) Ligand 28 (CCL28) Interaction Partners

Cow (Bovine) Chemokine (C-C Motif) Ligand 28 (CCL28) interaction partners

  1. Results identified chemotactic and antimicrobial properties of bCCL28 indicating that this chemokine (show CCL1 Proteins) may contribute to immune protection of the mammary gland, and the resolution or prevention of bovine mastitis.

Human Chemokine (C-C Motif) Ligand 28 (CCL28) interaction partners

  1. CCL28 was absent in saliva of primary Sjogren's syndrome patients. This finding did not correlate with salivary IgA levels.

  2. disease severity of atopic dermatitis in children is not correlated to the level of CCL28, but rather related to that of total IgE

  3. CCL28 (show ENC1 Proteins)-CCR3 (show CCR3 Proteins) interactions are involved in the homeostatic trafficking of CD4 (show CD4 Proteins)(+) T cells to the upper airways.

  4. High CCL28 (show ENC1 Proteins) gene methylation is associated with gastric tumor aggressiveness.

  5. CCL28 (show ENC1 Proteins) is a potent growth-promoting factor with the ability to support the in vitro and in vivo functional properties of cultured human hematopoietic cells.

  6. These results indicate a role for IL-17A in the human lung by enhancing the expression of CCL28 and hence driving the recruitment of IgE-secreting B cells.

  7. tumour hypoxia promotes the recruitment of regulatory T (T(reg (show EXTL3 Proteins))) cells through induction of expression of the chemokine (show CCL1 Proteins) CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis

  8. CCL28 (show ENC1 Proteins) may play dual roles in mucosal immunity as a chemoatt (show CCL1 Proteins)ractant for cells expressing CCR10 (show CCR10 Proteins) and/or CCR3 (show CCR3 Proteins) such as plasma cells and also as a broad-spectrum antimicrobial protein secreted into low-salt body fluids.

  9. CCR10 and its mucosal epithelial ligand CCL28 have roles in the migration of circulating IgA plasmablasts

  10. CCL28 (show ENC1 Proteins) produced by keratinocytes is mediated by different signal pathways from CCL27 (show CCL27 Proteins), and both CCL27 (show CCL27 Proteins) and CCL28 (show ENC1 Proteins) are involved in the pathogenesis of inflammatory skin diseases.

Pig (Porcine) Chemokine (C-C Motif) Ligand 28 (CCL28) interaction partners

  1. Mucosae associated-epithelial chemokine (MEC/CCL28) cloned from porcine salivary gland and colon tissues consisted of an open reading frame (ORF) of 384-bp coding for 127 amino-acids protein with 22 residues signal sequence.

Mouse (Murine) Chemokine (C-C Motif) Ligand 28 (CCL28) interaction partners

  1. Plasmid codelivery of murine CCL19 (show CCL19 Proteins) and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1 (show HAND1 Proteins)/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues.

  2. These data suggest that CCL28 could be useful in enhancing the IgA immune response that will likely play a pivotal role in prophylactic HIV vaccines.

  3. tumour hypoxia promotes the recruitment of regulatory T (T(reg (show KCNH2 Proteins))) cells through induction of expression of the chemokine (show CCL1 Proteins) CC-chemokine ligand 28 (CCL28), which, in turn, promotes tumour tolerance and angiogenesis

  4. demonstrate that interactions between the antimicrobial C-terminus of CCL28 with an appropriate CC chemokine (show CCL1 Proteins) N-terminal domain is important for the full antimicrobial activity of CCL28.

  5. CCL28 has dual functions in mucosal immunity as a chemokine (show CCL1 Proteins) attracting cells expressing CCR10 (show CCR10 Proteins) and/or CCR3 (show CCR3 Proteins) and also as an apically secreted molecule with a potent antimicrobial activity against a broad spectrum of microbes.

  6. MEC attracts IgA- but not IgG- or IgM-producing plasmablasts from both intestinal and nonintestinal lymphoid and effector tissues, including the intestines, lungs, and lymph nodes draining the bronchopulmonary tree and oral cavity.

  7. Epithelial cells and venular endothelium of both small intestine and colon are positive for CCL28; CCL28 plays a direct role in intestinal homing of IgA antibody-secreting cells by mediating their extravasation into intestinal lamina propria.

  8. CCL28 is a key regulator of IgA ASC accumulation in the mammary gland and thus controls the passive transfer of IgA antibodies from mother to infant.

  9. CCL28 appears to play a role in regulating eosinophil recruitment to peribronchial regions of the lung possibly by coordinated temporal production with eotaxin

  10. CCL28 mediates mucosal immunity in HIV exposure and infection

CCL28 Protein Profile

Protein Summary

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.

Gene names and symbols associated with CCL28

  • chemokine (C-C motif) ligand 28 (Ccl28)
  • chemokine (C-C motif) ligand 28 (CCL28)
  • C-C motif chemokine 28 (ccl28)
  • ectodermal-neural cortex (with BTB-like domain) (enc1)
  • CCL28 (LOC100303767)
  • CCK1 protein
  • ccl28 protein
  • enc-1 protein
  • Encr-3 protein
  • klhl35 protein
  • LOC100303767 protein
  • MEC protein
  • nrpb protein
  • pig10 protein
  • SCYA28 protein
  • tp53i10 protein
  • Xencr-3 protein

Protein level used designations for CCL28

C-C motif chemokine 28 , CC chemokine CCL28 , chemokine ligand 28 , chemokine CCL28/MEC , chemokine (C-C motif) ligand 28 , ectodermal-neural cortex (with BTB-like domain) , ectoderm neural cortex related-3 , CCL28 , chemokine (C-C motif) ligand 28 splice variant chi , mucosae-associated epithelial chemokine , small inducible cytokine A28 , small inducible cytokine subfamily A (Cys-Cys), member 28 , small-inducible cytokine A28 , chemokine CCL28 , mucosae-associated epithelial chemokine CCL28 , CC chemokine ligand 28

GENE ID SPECIES
114492 Rattus norvegicus
535328 Bos taurus
574221 Macaca mulatta
735978 Pan troglodytes
780500 Ovis aries
100196449 Salmo salar
100271761 Xenopus (Silurana) tropicalis
100303767 Oryctolagus cuniculus
56477 Homo sapiens
554303 Sus scrofa
56838 Mus musculus
448795 Canis lupus familiaris
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