CCL28 Protein

Catalog No. ABIN7455692

This Recombinant CCL28 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CCL28 Protein (ABIN7455692)

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: Greater than 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human C-C Motif Chemokine 28 is produced by our E.coli expression system and the target gene encoding Ser20-Tyr127 is expressed.

Characteristics: Extracellular Domain Protein

Purification: Affinity purification

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: CCL28

Background: C-C Motif Chemokine 28,Mucosae-Associated Epithelial Chemokine,MEC,Protein CCK1,Small-Inducible Cytokine A28,CCL28,SCYA28
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83 % sequence identity in their mature regions.

Molecular Weight: 12.49 KDa

UniProt: Q9NRJ3