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Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Additionally we are shipping CCR10 Kits (4) and CCR10 Proteins (4) and many more products for this protein.
Showing 10 out of 87 products:
Human Monoclonal CCR10 Primary Antibody for FACS - ABIN2662918
Homey, Alenius, Müller, Soto, Bowman, Yuan, McEvoy, Lauerma, Assmann, Bünemann, Lehto, Wolff, Yen, Marxhausen, To, Sedgwick, Ruzicka, Lehmann, Zlotnik: CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. in Nature medicine 2002
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Human Monoclonal CCR10 Primary Antibody for BR, FACS - ABIN2664100
Nakayama, Fujisawa, Izawa, Hieshima, Takada, Yoshie: Human B cells immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5. in Journal of virology 2002
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Human Monoclonal CCR10 Primary Antibody for FACS, CyTOF - ABIN2658423
Kunkel, Kim, Lazarus, Vierra, Soler, Bowman, Butcher: CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. in The Journal of clinical investigation 2003
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Human Polyclonal CCR10 Primary Antibody for WB - ABIN657666
Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010
Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.
some cells, including plasmacytoid dendritic cells, can express both CCR2 (show CCR2 Antibodies) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (show CCL2 Antibodies)-scavenging potential in vitro and in vivo; and that CCR2 (show CCR2 Antibodies) is a much more effective CCL2 (show CCL2 Antibodies) scavenger than ACKR2.
Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 (show CCL27 Antibodies) level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue
Chemokine (show CCL1 Antibodies) decoy receptor D6 limits CC-chemokine (show CCL1 Antibodies)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.
control of CCR2 ligands by D6 regulates the traffic of Ly6C(high) monocytes and controls their immunosuppressive potential.
D6, by suppressing inflammatory chemokine (show CCL1 Antibodies) binding to lymphatic surfaces, and thereby preventing inflammatory leukocyte adherence, is a regulator of lymphatic function and a contributor to the integration of innate and adaptive immune responses.
identify novel D6(active) B1-cell subsets, including those we term B1d, which lack CD5 (show CD5 Antibodies) and CD11b (show ITGAM Antibodies) but exhibit typical B1-cell properties, including spontaneous ex vivo production of IgM (show CD40LG Antibodies), IL-10 (show IL10 Antibodies), and anti-phosphorylcholine antibody
These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development
the chemokine (show CCL1 Antibodies) scavenger receptor D6 has a non-redundant role in acute toxic liver injury in vivo; results support the importance of post-translational chemokine (show CCL1 Antibodies) regulation and describe a new mechanism of immune modulation within the liver
CCR10 engagement by locally produced CCL27 (show CCL27 Antibodies) allows melanoma cells to escape host immune antitumor killing mechanisms (possibly through activation of PI3K/Akt (show AKT1 Antibodies)), thereby providing a means for tumor progression
Findings support the notion that CCR10 and its ligand CCL27 (show CCL27 Antibodies) may contribute to the skin infiltration of malignant T-cells in mycosis fungoides and adult T-cell leukemia/lymphoma.
low CCL27 (show CCL27 Antibodies)/CCR10 and CXCL12 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies) intratumoral mRNA ratios are associated with melanoma progression
CCR7 (show CCR7 Antibodies) overexpression correlated with expression of metallothionein (show MT Antibodies), while CCR10 was associated with cerebral metastases. CCR7 (show CCR7 Antibodies) and CCR10 overexpressions were associated with a worse outcome independent of Breslow's tumor thickness and Clark level.
unlike blood plasmacytoid dendritic cells (pDCs), a subset of tonsil pDCs express functional CCR6 (show CCR6 Antibodies) and CCR10, and their respective ligands CCL20 (show CCL20 Antibodies) and CCL27 (show CCL27 Antibodies) are detected in inflamed epithelia
The high fraction of circulating IgA+ and IgG+ B cells expressing CCR9 (show CCR9 Antibodies) and CCR10 in the first months of life indicates activation of naive B cells in the gut (show GUSB Antibodies), coinciding with bacterial colonization.
TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells.
CCR10 and its ligand CCL27 (show CCL27 Antibodies) may contribute to the skin infiltration of malignant T-cells in cutaneous T-cell lymphoma.
gene expression of CCR10 was increased by recombinant ANXA1 (show ANXA1 Antibodies) and the N-terminal ANXA1 (show ANXA1 Antibodies) peptide
CCR10-CTACK/CCL27 (show CCL27 Antibodies) interactions between circulating T cells and keratinocytes would seem to play an important role in the pathophysiology of mycosis fungoides.
CCR10 allows T regulatory (Treg) cells recruited to chronically inflamed liver tissues to respond to CCL28 (show ENC1 Antibodies) secreted by epithelial cells, resulting in the accumulation of CCR10+ Tregs at mucosal surfaces.
Study showed bovine CCL28 (show CCL28 Antibodies) mediating cellular chemotaxis via CCR10 chemokine receptor (show CCR1 Antibodies).
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues\; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27\; MIM 604833)\; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002
CC chemokine receptor 10
, chemokine C-C motif receptor 10
, C-C chemokine receptor D6
, D6 beta-chemokine receptor
, chemokine binding protein 2
, chemokine-binding protein 2
, chemokine-binding protein D6
, C-C CKR-10
, C-C chemokine receptor type 10
, G protein-coupled receptor 2
, G-protein coupled receptor 2
, chemokine C-C receptor 9