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Chemokine (C-C Motif) Receptor 10 Proteins (CCR10)

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Additionally we are shipping CCR10 Antibodies (86) and CCR10 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCR10 59289 O08707
CCR10 2826 P46092
Rat CCR10 CCR10 363682  
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Top CCR10 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

CCR10 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Chemokine (C-C Motif) Receptor 10 (CCR10) Interaction Partners

Mouse (Murine) Chemokine (C-C Motif) Receptor 10 (CCR10) interaction partners

  1. Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.

  2. some cells, including plasmacytoid dendritic cells, can express both CCR2 (show CCR2 Proteins) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (show CCL2 Proteins)-scavenging potential in vitro and in vivo; and that CCR2 (show CCR2 Proteins) is a much more effective CCL2 (show CCL2 Proteins) scavenger than ACKR2.

  3. Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 (show CCL27 Proteins) level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue

  4. Chemokine (show CCL1 Proteins) decoy receptor D6 limits CC-chemokine (show CCL1 Proteins)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.

  5. control of CCR2 ligands by D6 regulates the traffic of Ly6C(high) monocytes and controls their immunosuppressive potential.

  6. D6, by suppressing inflammatory chemokine (show CCL1 Proteins) binding to lymphatic surfaces, and thereby preventing inflammatory leukocyte adherence, is a regulator of lymphatic function and a contributor to the integration of innate and adaptive immune responses.

  7. identify novel D6(active) B1-cell subsets, including those we term B1d, which lack CD5 (show CD5 Proteins) and CD11b (show ITGAM Proteins) but exhibit typical B1-cell properties, including spontaneous ex vivo production of IgM (show CD40LG Proteins), IL-10 (show IL10 Proteins), and anti-phosphorylcholine antibody

  8. These findings provide definite evidence that CCR10 is important in skin intraepithelial Vgamma3(+) T lymphocyte development

  9. the chemokine (show CCL1 Proteins) scavenger receptor D6 has a non-redundant role in acute toxic liver injury in vivo; results support the importance of post-translational chemokine (show CCL1 Proteins) regulation and describe a new mechanism of immune modulation within the liver

  10. Blocking CCR4 (show CCR4 Proteins) and CCR10 simultaneously, or their ligands, should be beneficial in the treatment of T-cell-mediated skin diseases.

Human Chemokine (C-C Motif) Receptor 10 (CCR10) interaction partners

  1. Findings support the notion that CCR10 and its ligand CCL27 (show CCL27 Proteins) may contribute to the skin infiltration of malignant T-cells in mycosis fungoides and adult T-cell leukemia/lymphoma.

  2. low CCL27 (show CCL27 Proteins)/CCR10 and CXCL12 (show CXCL12 Proteins)/CXCR4 (show CXCR4 Proteins) intratumoral mRNA ratios are associated with melanoma progression

  3. CCR7 (show CCR7 Proteins) overexpression correlated with expression of metallothionein (show MT Proteins), while CCR10 was associated with cerebral metastases. CCR7 (show CCR7 Proteins) and CCR10 overexpressions were associated with a worse outcome independent of Breslow's tumor thickness and Clark level.

  4. unlike blood plasmacytoid dendritic cells (pDCs), a subset of tonsil pDCs express functional CCR6 (show CCR6 Proteins) and CCR10, and their respective ligands CCL20 (show CCL20 Proteins) and CCL27 (show CCL27 Proteins) are detected in inflamed epithelia

  5. The high fraction of circulating IgA+ and IgG+ B cells expressing CCR9 (show CCR9 Proteins) and CCR10 in the first months of life indicates activation of naive B cells in the gut (show GUSB Proteins), coinciding with bacterial colonization.

  6. TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells.

  7. CCR10 and its ligand CCL27 (show CCL27 Proteins) may contribute to the skin infiltration of malignant T-cells in cutaneous T-cell lymphoma.

  8. gene expression of CCR10 was increased by recombinant ANXA1 (show ANXA1 Proteins) and the N-terminal ANXA1 (show ANXA1 Proteins) peptide

  9. CCR10-CTACK/CCL27 (show CCL27 Proteins) interactions between circulating T cells and keratinocytes would seem to play an important role in the pathophysiology of mycosis fungoides.

  10. CCR10 allows T regulatory (Treg) cells recruited to chronically inflamed liver tissues to respond to CCL28 (show ENC1 Proteins) secreted by epithelial cells, resulting in the accumulation of CCR10+ Tregs at mucosal surfaces.

Cow (Bovine) Chemokine (C-C Motif) Receptor 10 (CCR10) interaction partners

  1. Study showed bovine CCL28 (show CCL28 Proteins) mediating cellular chemotaxis via CCR10 chemokine receptor (show CCR1 Proteins).

CCR10 Protein Profile

Protein Summary

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues\; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27\; MIM 604833)\; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002

Gene names and symbols associated with CCR10

  • chemokine (C-C motif) receptor 10 (ccr10)
  • chemokine (C-C motif) receptor 10 (CCR10)
  • atypical chemokine receptor 2 (Ackr2)
  • chemokine (C-C motif) receptor 10 (Ccr10)
  • AI464239 protein
  • Ccbp2 protein
  • CCR9 protein
  • CCR10 protein
  • Cmkbr9 protein
  • D6 protein
  • Gpr2 protein
  • zgc:91924 protein

Protein level used designations for CCR10

CC chemokine receptor 10 , chemokine C-C motif receptor 10 , C-C chemokine receptor D6 , D6 beta-chemokine receptor , chemokine binding protein 2 , chemokine-binding protein 2 , chemokine-binding protein D6 , C-C CKR-10 , C-C chemokine receptor type 10 , CC-CKR-10 , CCR-10 , G protein-coupled receptor 2 , G-protein coupled receptor 2 , chemokine C-C receptor 9

GENE ID SPECIES
436948 Danio rerio
678671 Ovis aries
741917 Pan troglodytes
59289 Mus musculus
2826 Homo sapiens
12777 Mus musculus
363682 Rattus norvegicus
607528 Canis lupus familiaris
733623 Sus scrofa
539108 Bos taurus
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