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Chemokine (C-C Motif) Receptor-Like 2 Proteins (CCRL2)

CCRL2 encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Additionally we are shipping CCRL2 Antibodies (64) and CCRL2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CCRL2 CCRL2 316019  
CCRL2 9034 O00421
CCRL2 54199 O35457
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Top CCRL2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

CCRL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) Interaction Partners

Human Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) interaction partners

  1. CCRL2 inhibited the growth of breast cancer cells in vitro and in vivo.

  2. in breast cancer, CRAM-A becomes specifically upregulated under inflammatory stimuli and may serve as a potential marker of immune response.

  3. these results suggest for the first time that elevated CCRL2 in glioma promotes cell migration and invasion.

  4. Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor (show CCR1 Proteins) may affect pneumocystis pneumonia through immune regulation and inducing inflammation.

  5. demonstration that the homeostatic chemokine CCL19 (show CCL19 Proteins) is a specific ligand for CRAM

  6. CCRL2 expression is up-regulated on synovial neutrophils of rheumatoid arthritis patients

  7. Results identify chemerin (show RARRES2 Proteins) as a natural nonsignaling protein ligand for both human and mouse CCRL2.

Mouse (Murine) Chemokine (C-C Motif) Receptor-Like 2 (CCRL2) interaction partners

  1. Proinflammatory stimuli upregulate atypical chemerin receptor (show CMKLR1 Proteins) CCRL2 and VCAM-1 (show VCAM1 Proteins) on endothelial cells via NF-kappaB (show NFKB1 Proteins) and JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) intracellular signaling pathways.

  2. Ccrl2(-/-) mice showed normal recruitment of circulating dendritic cells (DC) into the lung, but a defective trafficking of antigen-loaded lung DC to mediastinal lymph nodes.

  3. Expression of L-CCR mRNA is reported in murine astrocytes and microglia and is greatly enhanced under proinflammatory conditions; this receptor may play a role in neuroinflammatory processes.

  4. Prominent expression of L-CCR mRNA is detected in astrocytes and microglia at early time points throughout the brain and spinal cord in experimental autoimmune encephalomyelitis supporting the proposed relationship of L-CCR expression to CNS inflammation.

  5. Results identify chemerin (show RARRES2 Proteins) as a natural nonsignaling protein ligand for both human and mouse CCRL2.

CCRL2 Protein Profile

Protein Summary

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

Gene names and symbols associated with CCRL2

  • chemokine (C-C motif) receptor-like 2 (Ccrl2)
  • chemokine (C-C motif) receptor-like 2 (CCRL2)
  • chemokine C-C motif receptor-like 2-like (LOC515976)
  • 1810047I05Rik protein
  • Ackr5 protein
  • CCR11 protein
  • CCRL2 protein
  • CKRX protein
  • Cmkbr1l2 protein
  • CRAM protein
  • CRAM-A protein
  • CRAM-B protein
  • E01 protein
  • HCR protein
  • L-CCR protein

Protein level used designations for CCRL2

C-C chemokine receptor-like 2 , chemokine (C-C motif) receptor-like 2 , c-C chemokine receptor-like 2-like , atypical chemokine receptor 5 , chemokine receptor CCR11 , chemokine receptor X , putative MCP-1 chemokine receptor , G-protein coupled beta chemokine receptor , chemokine (C-C) receptor 1,-like 2 , chemokine (C-C) receptor 1-like 2 , lipopolysaccharide inducible C-C chemokine receptor related , lipopolysaccharide-inducible C-C chemokine receptor , lipopolysacharide-inducible C-C chemokine receptor , chemokine C-C motif receptor-like 2

GENE ID SPECIES
316019 Rattus norvegicus
460324 Pan troglodytes
484788 Canis lupus familiaris
100439180 Pongo abelii
100582482 Nomascus leucogenys
9034 Homo sapiens
54199 Mus musculus
414370 Sus scrofa
515976 Bos taurus
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