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CXCL12 encodes a stromal cell-derived alpha chemokine member of the intercrine family. Additionally we are shipping CXCL12 Proteins (145) and CXCL12 Kits (76) and many more products for this protein.
Showing 10 out of 156 products:
Chicken Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605
Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004
Show all 2 references for ABIN2774605
Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
Show all 2 references for ABIN1386329
Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal CXCL12 Primary Antibody for IHC, WB - ABIN2160439
de Paz, Moseman, Noti, Polito, von Andrian, Seeberger: Profiling heparin-chemokine interactions using synthetic tools. in ACS chemical biology 2007
these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs
Study shows that serum concentrations of CXCL12 were significantly higher, while those of its receptor CXCR4 (show CXCR4 Antibodies) were significantly lower in esophageal cancer (EC) patients suggesting that suggest that serum CXCR4 (show CXCR4 Antibodies) and CXCl12 may improve the diagnosis of EC patients.
Data suggest targeting the stromal cell-derived factor-1 (SDF-1)/chemokine receptor 4 (CXCR4) axis might provide a therapeutic strategy for endometrial cancer (EC) treatment.
In breast cancer patients, CXCL12 exhibited significant differences in expression between primary tumor and lymph node metastasis tumor
We conclude that the CXCL12 G801A polymorphism is a risk factor that increases susceptibility to gliomas in a subset of the general Han Chinese population.
these results indicate that the chemokine receptor CXCR4 (show CXCR4 Antibodies) and its ligand CXCL12 play important roles in the occurrence and development of bladder cancer.
mRNA expression of SDF-1 was significantly elevated in colorectal cancer.
CXCL12 could trigger epithelial to mesenchymal transition of breast cancer cells.
that elevated serum CXCL12 level at admission was an independent diagnostic and prognostic marker in patients with acute ischemic stroke
Its remarkable effect on inhibiting CXCR4 (show CXCR4 Antibodies)/CXCL12-mediated adhesion and migration of AML (show RUNX1 Antibodies) cells.
Endomyocardial expression of SDF-1 is enhanced in inflammatory cardiomyopathy, positively correlates with myocardial fibrosis and identifies high-risk patients with suspected myocarditis.
confirm a pivotal role of the SDF-1/CXCR4 (show CXCR4 Antibodies)/CXCR7 (show CXCR7 Antibodies) axis for chronic allograft vasculopathy development
Time-dependent changes in endometrial hypoxia during menstruation correlated with the regulation of mRNAs encoding for the angiogenic genes Vegfa (show VEGFA Antibodies) and Cxcl12.
The results of this study findings the post-CNS-inflammation role of CXCL12 in augmenting the endogenous myelin/neuronal repair capacity in MS-like disease, likely via CXCL12/CXCR4 (show CXCR4 Antibodies) autocrine signaling.
CXCR4 (show CXCR4 Antibodies)/CXCL12 signaling may control movement of epithelial progenitors from the dental stem cell niche.
our present study provided evidence that SDF-1 mediated CSCs migration through CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) via MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) and PI3K/Akt (show AKT1 Antibodies) pathway
Following fracture, a CXCL12(+)-BMP2 (show BMP2 Antibodies)(+) perivascular cell population is recruited along the endosteum.
Data suggest that the conditional chemokine (show CCL1 Antibodies) CXCL12 line can be used as a powerful tool to manipulate CXCL12 signaling and function in vivo.
SDF-1 expressed by liver sinusoidal endothelial cells can be a major player in the recruitment of hematopoietic stem and progenitor cells to the liver during extramedullary hematopoiesis induced by hematopoietic mobilizers
EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.
Combination of bone morphogenetic protein-2 (show BMP2 Antibodies) plasmid DNA with chemokine (show CCL1 Antibodies) CXCL12 creates an additive effect on bone formation
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, stromal cell-derived factor 1a
, intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma