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anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) Antibodies

CXCL12 encodes a stromal cell-derived alpha chemokine member of the intercrine family. Additionally we are shipping CXCL12 Proteins (145) and CXCL12 Kits (76) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCL12 6387 P48061
CXCL12 20315 P40224
CXCL12 24772  
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Top anti-CXCL12 Antibodies at

Showing 10 out of 156 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-SD... 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated EIA, Func, IHC (p), WB   50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
Human Goat Un-conjugated EIA, Func, IHC (p), WB   50 μg Log in to see 10 to 12 Days
Human Rabbit Biotin EIA, WB   25 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Human Skin, Fibroblasts (formalin-fixed, paraffin-embedded) stained wi... Human Breast, Fibroblasts (formalin-fixed, paraffin-embedded) stained ... 50 μg Log in to see 8 to 10 Days
Mouse Rabbit Un-conjugated WB Western blot with SDF1 alpha antibody: Lane 1: 10 ng Recombinant mouse... 100 μg Log in to see 2 to 3 Days
Dog Rabbit Un-conjugated IP, WB Western blot analysis of CXCL12 expression in Jurkat (A), NCIH292 (B) ... 200 μL Log in to see 9 Days
Rat Rabbit Un-conjugated IHC (p), IP, WB Human Thymus (formalin-fixed, paraffin-embedded) stained with CXCL12 a... 50 μg Log in to see 8 to 10 Days

CXCL12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CXCL12 Antibodies

  1. Chicken Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605 : Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN2774605

  2. Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329 : Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014 (PubMed)
    Show all 2 references for ABIN1386329

  3. Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227 : Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  4. Human Polyclonal CXCL12 Primary Antibody for IHC, WB - ABIN2160439 : de Paz, Moseman, Noti, Polito, von Andrian, Seeberger: Profiling heparin-chemokine interactions using synthetic tools. in ACS chemical biology 2007 (PubMed)

More Antibodies against CXCL12 Interaction Partners

Rhesus Monkey Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells

  2. following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.

  3. The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

Medaka Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs

Human Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. CXCL12 could trigger epithelial to mesenchymal transition of breast cancer cells.

  2. that elevated serum CXCL12 level at admission was an independent diagnostic and prognostic marker in patients with acute ischemic stroke

  3. Its remarkable effect on inhibiting CXCR4 (show CXCR4 Antibodies)/CXCL12-mediated adhesion and migration of AML (show RUNX1 Antibodies) cells.

  4. Endomyocardial expression of SDF-1 is enhanced in inflammatory cardiomyopathy, positively correlates with myocardial fibrosis and identifies high-risk patients with suspected myocarditis.

  5. extremely high levels of SDF-1 provide a crucial microenvironment for epidermal keratinocyte proliferation in both physiologic and pathologic skin conditions

  6. Blood fibrocytes are recruited during COPD (show ARCN1 Antibodies) exacerbations and related to mortality and low lung function. The CXCL12/CXCR4 (show CXCR4 Antibodies) axis is involved in such fibrocyte recruitment.

  7. Membranous expression of SDF-1 was a marker of poor prognosis and proved to be an independent prognostic parameter for the entire cohort and for patients with adenocarcinoma

  8. Developmental expression patterns of chemokines CXCL11 (show CXCL11 Antibodies), CXCL12 and their receptor CXCR7 (show CXCR7 Antibodies) in testes

  9. documented that CXCL12-3'A polymorphic variant can facilitate hematopoietic stem cell transplantation outcome from unrelated donors; presence of the CXCL12-3'A allele was found to be associated with a lower risk of early viral and toxic complications, as well as decreased risk of aGvHD if present in donor or recipient genotype

  10. This suggests that N-WASP's failure to compensate for WASP (show WASL Antibodies) in rescuing chemotaxis could be due to the absence of this I30 region.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Time-dependent changes in endometrial hypoxia during menstruation correlated with the regulation of mRNAs encoding for the angiogenic genes Vegfa (show VEGFA Antibodies) and Cxcl12.

  2. The results of this study findings the post-CNS-inflammation role of CXCL12 in augmenting the endogenous myelin/neuronal repair capacity in MS-like disease, likely via CXCL12/CXCR4 (show CXCR4 Antibodies) autocrine signaling.

  3. CXCR4 (show CXCR4 Antibodies)/CXCL12 signaling may control movement of epithelial progenitors from the dental stem cell niche.

  4. our present study provided evidence that SDF-1 mediated CSCs migration through CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) via MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) and PI3K/Akt (show AKT1 Antibodies) pathway

  5. Following fracture, a CXCL12(+)-BMP2 (show BMP2 Antibodies)(+) perivascular cell population is recruited along the endosteum.

  6. Data suggest that the conditional chemokine (show CCL1 Antibodies) CXCL12 line can be used as a powerful tool to manipulate CXCL12 signaling and function in vivo.

  7. SDF-1 expressed by liver sinusoidal endothelial cells can be a major player in the recruitment of hematopoietic stem and progenitor cells to the liver during extramedullary hematopoiesis induced by hematopoietic mobilizers

  8. EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.

  9. Combination of bone morphogenetic protein-2 (show BMP2 Antibodies) plasmid DNA with chemokine (show CCL1 Antibodies) CXCL12 creates an additive effect on bone formation

  10. Independent of the reduction of blood pressure, aliskiren enhanced ischemia-induced neovasculogenesis in a dose-dependent manner via VEGF/SDF-1alpha related mechanisms in diabetic mice.

Xenopus laevis Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7

  2. SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus

  3. A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.

  4. SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.

  2. Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle

CXCL12 Antigen Profile

Protein Summary

This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CXCL12

  • chemokine (C-X-C motif) ligand 12 (CXCL12) antibody
  • CXCL12 (LOC100304642) antibody
  • stromal cell-derived factor 1a (sdf1a) antibody
  • stromal cell-derived factor 1a (a-sdf1a) antibody
  • chemokine (C-X-C motif) ligand 12 (Cxcl12) antibody
  • chemokine (C-X-C motif) ligand 12 (cxcl12) antibody
  • a-sdf1a antibody
  • IRH antibody
  • Pbsf antibody
  • Scyb12 antibody
  • SDF-1 antibody
  • sdf1 antibody
  • sdf1a antibody
  • Tlsf antibody
  • Tpar1 antibody
  • xSDF-1 antibody

Protein level used designations for CXCL12

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) , chemokine CXCL12/SDF-1ALPHA , stromal cell-derived factor 1 , stromal cell-derived factor 1 isoform alpha , stromal cell-derived factor 1 isoform gamma , CXCL12 , stromal cell-derived factor 1a , intercrine reduced in hepatomas , pre-B cell growth-stimulating factor , 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 , pre-B-cell growth-stimulating factor , thymic lymphoma cell-stimulating factor , C-X-C motif chemokine 12 , stromal-derived factor 1 , chemokine ligand 12b , stromal cell derived factor 1 , stromal cell-derived factor-1 beta , CXC chemokine , CXCL12 chemokine , SDF-1 gamma , Stromal cell-derived factor 1 , stromal cell-derived factor-1 gamma

574334 Macaca mulatta
100173045 Pongo abelii
100304642 Ictalurus punctatus
100049305 Oryzias latipes
100170634 Oryzias latipes
6387 Homo sapiens
20315 Mus musculus
399030 Xenopus laevis
395180 Gallus gallus
449622 Canis lupus familiaris
494460 Sus scrofa
613811 Bos taurus
24772 Rattus norvegicus
100721137 Cavia porcellus
493806 Felis catus
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