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CXCL12 encodes a stromal cell-derived alpha chemokine member of the intercrine family. Additionally we are shipping CXCL12 Proteins (147) and CXCL12 Kits (60) and many more products for this protein.
Showing 10 out of 186 products:
Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329
Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014
Show all 3 references for ABIN1386329
Chicken Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605
Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004
Show all 2 references for ABIN2774605
Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227
Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal CXCL12 Primary Antibody for IHC, WB - ABIN2160439
de Paz, Moseman, Noti, Polito, von Andrian, Seeberger: Profiling heparin-chemokine interactions using synthetic tools. in ACS chemical biology 2007
these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs
Data suggest that microRNA miR (show MLXIP Antibodies)-454 specifically targets 3' untranslated region (3'-UTR (show UTS2R Antibodies)) of stromal cell derived factor-1 (SDF-1) mRNA to inhibit its translation.
These results indicate that in gingiva, upon allergen exposure, MUTZ-3 LC migrate in a CXCL12 independent manner from epithelium-to-lamina propria and in doing so mature become CD1a (show CD1A Antibodies)- and increase CD83 (show CD83 Antibodies)+ mRNA.
The SDF-1 rs1801157 G>A polymorphism demonstrated no significant differences in genotype distributions and allele frequency between acute myeloid leukemia (show BCL11A Antibodies) patients and healthy controls.
sorafenib-induced increase of SDF1-alpha expression in paratumor and intratumor microenvironments is suppressed by aspirin, which is associated with aspirin-mediated suppression of the pro-metastasis effect of sorafenib in hepatocellular carcinoma
These findings suggested Epac (show RAPGEF3 Antibodies) is connected to the SDF-1 signaling cascades. In conclusion, our study revealed that Epac (show RAPGEF3 Antibodies) plays a role in human mesenchymal stem cells (hMSCs)homing by promoting adhesion and migration. Appropriate manipulation of Epac (show RAPGEF3 Antibodies) may enhance the homing of hMSCs and facilitate their future clinical applications.
In this study HL-60 cells were treated with SDF-1/CXCL12 for 2 and 24h. Oxygen consumption rates (OCR), mitochondrial-associated ATP production, mitochondrial mass, and mitochondrial membrane potential of HL-60 cells were significantly reduced at 2h and increased at 24h as compared to untreated control cells.
SDF-1 and VEGF (show VEGFA Antibodies) expression levels were both significantly associated with osteosarcoma, and SDF-1 expression is a potential independent prognostic indicator in patients with osteosarcoma.
Results show that CXCL12 expression was increased in papillary thyroid carcinoma (PTC (show F9 Antibodies)) tissues and was inversely correlated with miR (show MLXIP Antibodies)-137 which binds to its 3'UTR (show UTS2R Antibodies).
Low plasma SDF-1 is associated with high mortality in African Americans with type 1 diabetes.
CXCL12 and percentage embryonal carcinoma both stratify patients' relapse risk over and above vascular invasion alone
crosstalk between astrocytic CXCL12 and microglial CXCR4 (show CXCR4 Antibodies) in the pathogenesis of neuropathic pain.
A model of SDF-1 regulation in the hypoxia pathway was constructed; the underlying mechanisms of SDF-1 kinetics and a novel incoherent feed forward loop regulating SDF-1 expression were proposed.
We showed that CXCL12, a potent chemoattractant for CXCR4 (show CXCR4 Antibodies)-expressing NSPCs, was upregulated in the ischemic lesion of N-PRbeta-KO mice.
DPP-4 (show DPP4 Antibodies) inhibition may have direct protective effects on the post-myocardial infarction heart by inducing an antiapoptotic effect and inhibiting a decrease in vessel number through the SDF-1a/CXCR4 (show CXCR4 Antibodies)-mediated STAT3 (show STAT3 Antibodies) signaling pathway.
findings demonstrate that Twist-1 (show TWIST1 Antibodies), which maintains BMSC at an immature state, endows them with an increased capacity for supporting hematopoiesis via direct activation of CXCL12 gene expression.
confirm a pivotal role of the SDF-1/CXCR4 (show CXCR4 Antibodies)/CXCR7 (show CXCR7 Antibodies) axis for chronic allograft vasculopathy development
Time-dependent changes in endometrial hypoxia during menstruation correlated with the regulation of mRNAs encoding for the angiogenic genes Vegfa (show VEGFA Antibodies) and Cxcl12.
The results of this study findings the post-CNS-inflammation role of CXCL12 in augmenting the endogenous myelin/neuronal repair capacity in MS-like disease, likely via CXCL12/CXCR4 (show CXCR4 Antibodies) autocrine signaling.
CXCR4 (show CXCR4 Antibodies)/CXCL12 signaling may control movement of epithelial progenitors from the dental stem cell niche.
our present study provided evidence that SDF-1 mediated CSCs migration through CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) via MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) and PI3K/Akt (show AKT1 Antibodies) pathway
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, stromal cell-derived factor 1a
, intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma