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Chemokine (C-X3-C Motif) Receptor 1 Proteins (CX3CR1)

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. Additionally we are shipping CX3CR1 Antibodies (184) and CX3CR1 Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CX3CR1 CX3CR1 171056 P35411
CX3CR1 1524 P49238
CX3CR1 13051 Q9Z0D9
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Top CX3CR1 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

CX3CR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Interaction Partners

Human Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) interaction partners

  1. CX3CR1 is expressed in the normal, cancer adjacent normal, inflammatory, and malignant fallopian epithelium.

  2. CX3CR1 T allele of rs3732379 might have a positive association with the susceptibility of age-related macular degeneration

  3. CX3CR1 is expressed differentially in human monocytes during differentiation.

  4. This meta-analysis suggested that CX3CR1 T280M and V249I polymorphisms may not be associated with an increased risk of AMD (show AMD1 Proteins) based on current published data.

  5. Data show that fractalkine receptor CX3CR1 expression is decreased in both murine and human glioblastoma (GBM) tissue.

  6. Respiratory syncytial virus G protein and host CX3CR1 interaction is important in infection and infection-induced responses of the airway epithelium.

  7. Association of hydrogen sulfide (show SQRDL Proteins) with alterations of monocyte chemokine (show CCL1 Proteins) receptors, CCR2 (show CCR2 Proteins) and CX3CR1 in patients with coronary artery disease

  8. Specific pro-inflammatory monocyte subpopulations positive for CD16 (show CD16 Proteins) and the co-expressed chemokine receptor (show CCR1 Proteins), CX3CR1, are discriminative for chronic kidney disease stage 5 on hemodialysis patients.

  9. CX3CR1 is expressed in differentiated human ciliated airway cells and co-localizes with respiratory syncytial virus on cilia in a G protein-dependent manner.

  10. CX3CL1 (show CX3CL1 Proteins) and CX3CR1 may contribute to the formation of coronary atherosclerotic plaque in coronary artery disease

Mouse (Murine) Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) interaction partners

  1. Some mononuclear phagocyte subsets that develop from monocytes and are distinguished by their expression of CX3CR1. CX3CR1 expression can be regulated using in vivo depletion techniques and genetic targeting.

  2. CD11c (show ITGAX Proteins)(+) CX3CR1(+) F4/80(-) DCs significantly increased during intestinal schistosomiasis in the ileal lamina propria

  3. activation of canonical Wnt (show WNT2 Proteins) signaling might contribute to the focal retinal degeneration of mouse models with Ccl2 (show CCL2 Proteins) and Cx3cr1 deficiency

  4. Results show that CX3CR1 knockout decreases phagocytosis in microglia resulting in decreased inflammation associated with alpha-syn internalization SUGGESTING THAT CX3CR1 is important in disease progression of synucleinopathies.

  5. Also icariin reduced CX3CR1 and CX3CL1 (show CX3CL1 Proteins) protein levels in the artery wall. In conclusion, icariin could be a potential anti-atherosclerosis agent by downregulating the expression of CX3CR1.

  6. Results of this study demonstrate for the first time that CX3CR1 modulates responses to mild TBI (show TBPL1 Proteins) in a time-dependent manner

  7. Results demonstrate that dysregulated microglial responses in absence of CX3CR1 contribute to inflammatory-mediated damage of neurons in the diabetic retina

  8. survival of resident arterial macrophages depends on a CX3CR1-CX3CL1 (show CX3CL1 Proteins) axis within the vascular niche.

  9. CX3CR1 is important to acute skeletal muscle injury repair by regulating macrophage phagocytosis.

  10. This study showed CX3CR1 deficiency promotes muscle repair and rescues Ccl2 (show CCL2 Proteins)(-/-) mice from impaired muscle regeneration as a result of altered macrophage function, including upregulated Apolipoprotein E (ApoE (show APOE Proteins)).

CX3CR1 Protein Profile

Protein Summary

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with CX3CR1

  • chemokine (C-X3-C motif) receptor 1 (CX3CR1)
  • chemokine (C-C motif) receptor-like 1 (CCRL1)
  • CX3C chemokine receptor 1-like (LOC100028655)
  • CX3C chemokine receptor 1-like (LOC100391413)
  • CX3C chemokine receptor 1-like (LOC100453042)
  • CX3C chemokine receptor 1-like (LOC100481132)
  • CX3C chemokine receptor 1-like (LOC100544445)
  • CX3C chemokine receptor 1-like (LOC100559882)
  • CX3C chemokine receptor 1-like (LOC100622126)
  • CX3C chemokine receptor 1-like (LOC100622491)
  • chemokine (C-X-C motif) receptor 1 (Cxcr1)
  • chemokine (C-X3-C motif) receptor 1 (Cx3cr1)
  • chemokine (C-X3-C) receptor 1 (Cx3cr1)
  • CCRL1 protein
  • CMKBRL1 protein
  • CMKDR1 protein
  • GPR13 protein
  • GPRV28 protein
  • Rbs11 protein
  • V28 protein

Protein level used designations for CX3CR1

CX3C chemokine receptor 1 , chemokine (C-C motif) receptor-like 1 , CX3C chemokine receptor 1-like , c-C chemokine receptor type 11-like , chemokine (C-X3-C motif) receptor 1 , C-X-C chemokine receptor type 1 , chemokine receptor CXCR1 , C-X3-C CKR-1 , chemokine (C-X3-C) receptor 1 , fractalkine receptor , CMK-BRL-1 , CMK-BRL1 , G protein-coupled receptor 13 , G-protein coupled receptor 13 , beta chemokine receptor-like 1 , chemokine (C-C) receptor-like 1 , Fractalkine receptor , chemokine receptor 1

GENE ID SPECIES
460281 Pan troglodytes
693926 Macaca mulatta
470928 Pan troglodytes
608898 Canis lupus familiaris
717701 Macaca mulatta
100028655 Monodelphis domestica
100391413 Callithrix jacchus
100440536 Pongo abelii
100453042 Pongo abelii
100481132 Ailuropoda melanoleuca
100544445 Meleagris gallopavo
100559882 Anolis carolinensis
100604041 Nomascus leucogenys
100622126 Sus scrofa
100622491 Sus scrofa
100379619 Cavia porcellus
171056 Rattus norvegicus
1524 Homo sapiens
485599 Canis lupus familiaris
100124525 Bos taurus
100008874 Oryctolagus cuniculus
100735615 Cavia porcellus
420719 Gallus gallus
101113016 Ovis aries
13051 Mus musculus
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