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CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Additionally we are shipping CCL18 Antibodies (66) and CCL18 Proteins (36) and many more products for this protein.
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Human CCL18 ELISA Kit for Sandwich ELISA - ABIN2683652
Genin, Clement, Fattaccioli, Raes, Michiels: M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide. in BMC cancer 2015
Matrigel invasion assays revealed that tumor ECM (show MMRN1 ELISA Kits)-educated macrophages efficiently stimulated cancer cell invasion through a mechanism involving CCL18.
Our results indicate that CCL18 acts in an autocrine manner via Akt (show AKT1 ELISA Kits) activation to stimulate oral squamous cell carcinoma cell growth and invasion during disease progression
Our data indicate that hypoxic inhibition of JMJD3 (show Kdm6b ELISA Kits) activity reduces demethylation of H3K27me3, nucleosome removal, and hence induction of the STAT6 (show STAT6 ELISA Kits) target gene CCL18, while induction of other STAT6 (show STAT6 ELISA Kits)-inducible genes such as SPINT2 (show SPINT2 ELISA Kits) remained unaffected by JMJD3 (show Kdm6b ELISA Kits).
There was no association between serial CCL18 concentrations with tumor response and overall survival.
CCL-18 is a promising biomarker in COPD (show ARCN1 ELISA Kits), as it is associated with frequency of exacerbations, particularly with severe COPD (show ARCN1 ELISA Kits) exacerbations requiring hospitalization, as well as with functional parameters and symptom scores.
Data suggested that CCL18 upregulated Slug expression to promote epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)) and stem cell-like features by activating the mTOR (show FRAP1 ELISA Kits) pathway in oral cancer.
An increased lung protein expression of PARC (show CUL9 ELISA Kits) in chronic obstructive pulmonary disease patients
CCL18 can increase the invasive ability of non-small cell lung cancer cells by binding to its receptor Nir1.
Results demonstrate that high levels of CCL18 are present in ovarian cancer (OC) ascites and that CCL18 is an important component of ascites for the ascites-mediated migration of OC cells. Ascites and CCL18 stimulate the phosphorylation and expression of Pyk2 (show PTK2B ELISA Kits), which is critical for mediated CCL18-induced migration.
Data suggest that circulating CCL18 and abdominal subcutaneous white adipose tissue-secreted CCL18 correlates with insulin (show INS ELISA Kits) resistance and metabolic syndrome risk score; because CCL18 is macrophage-specific and associates with adipose immune gene expression, it may constitute a marker of adipose tissue inflammation (panniculitis).
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
C-C motif chemokine 18
, CC chemokine PARC
, CC chemokine ligand 18
, alternative macrophage activation-associated CC chemokine 1
, chemokine (C-C), dendritic
, dendritic cell chemokine 1
, macrophage inflammatory protein 4
, pulmonary and activation-regulated chemokine
, small inducible cytokine A18
, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
, small-inducible cytokine A18
, chemokine CCL18/PARC