Chemokine (C-C Motif) Ligand 17 Proteins (CCL17)

CCL17 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Additionally we are shipping CCL17 Antibodies (188) and CCL17 Kits (65) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL17 6361 Q92583
CCL17 20295  
CCL17 117518  
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Top CCL17 Proteins at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 60 to 65 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$672.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$723.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$752.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Rhesus Monkey His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$103.27
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$114.15
Details

CCL17 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Top referenced CCL17 Proteins

  1. Human CCL17 Protein expressed in - ABIN620943 : García, Cidoncha, Bote, Hinchado, Ortega: Altered profile of chemokines in fibromyalgia patients. in Annals of clinical biochemistry 2014 (PubMed)

More Proteins for Chemokine (C-C Motif) Ligand 17 (CCL17) Interaction Partners

Human Chemokine (C-C Motif) Ligand 17 (CCL17) interaction partners

  1. TARC is a candidate biomarker for PTSD only in males.

  2. High CCL17 expression is associated with colon cancer cell migration.

  3. GM-CSF (show CSF2 Proteins) can mediate inflammation and pain by regulating IRF4 (show IRF4 Proteins)-induced CCL17 production

  4. Based on the ADEPT study data set, we report that airway mucosal expression of CCL26 (show CCL26 Proteins) was a robust discriminator of type 2 inflammation from healthy nonatopic subjects. Furthermore, airway mucosal CCL26 (show CCL26 Proteins) expression was best identified by using a panel of clinical biomarkers, including Feno values, bEOS counts, and expression of 2 novel markers, sCCL17 and sCCL26

  5. Low CCL17 expression is a potential independent adverse prognostic biomarker for recurrence and survival of patients with clear cell renal cell carcinoma (show MOK Proteins) after nephrectomy.

  6. IP-10 (show CXCL10 Proteins) serum increase or TARC/IP-10 (show CXCL10 Proteins) ratio decrease along with abnormal hepatic enzymatic alteration could signify early rejection of the transplanted liver.

  7. elevated pre-treatment levels of sGal-1, sCD163 (show CD163 Proteins), sCD30 and TARC can be found in patients with classic Hodgkin lymphoma. However, only plasma TARC accurately reflects disease activity and correlates with clinical treatment response.

  8. levels elevated in rheumatoid arthritis synovial fluid, due to production by mononuclear cells, particularly CD1c (show CD1C Proteins) classical dendritic cells

  9. Serum TARC levels are well correlated with blood eosinophil counts in patients with generalized drug eruptions, indicating that Th2-type immune reactions underlie TARC production. Serum TARC measurements also have potent diagnostic value for DIHS, with high sensitivity and specificity.

  10. Data suggest that Th1 (show TH1L Proteins) (IFN-gamma (show IFNG Proteins)-inducible protein-10 IP-10/CXCL10 (show CXCL10 Proteins)) and Th2 (thymus and activation regulated chemokine TARC/CCL17) and (macrophage derived chemokine MDC/CCL22 (show CCL22 Proteins)) cooperatively play a role in the development of ankylosing spondylitis (AS).

Mouse (Murine) Chemokine (C-C Motif) Ligand 17 (CCL17) interaction partners

  1. GM-CSF (show CSF2 Proteins) can mediate inflammation and pain by regulating IRF4 (show IRF4 Proteins)-induced CCL17 production

  2. the M2 macrophage chemokine CCL17 was identified as an essential factor for enhanced survival in the absence of CB2, because CCL17 x Cnr2 double-deficient mice were fully susceptible to experimental cerebral malaria.

  3. Aged mice had similar levels of IL-1beta (show IL1B Proteins), TNF (show TNF Proteins), IFN-gamma (show IFNG Proteins), IL-17 (show IL17A Proteins), and granulocyte colony-stimulating factor (show CSF3 Proteins) following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9 (show CXCL9 Proteins), CXCL12 (show CXCL12 Proteins), CCL3 (show CCL3 Proteins), CCL4 (show CCL4 Proteins), CCL5 (show CCL5 Proteins), CCL11, and CCL17.

  4. that effective engagement of CCR4 (show CCR4 Proteins) by CCL17 involves two distinct binding domains and interaction with both is required for signaling

  5. murine tumor-associated neutrophils secrete significant amounts of CCL17. Migration assays showed recruitment of T-regs by tumor-associated neutrophils, which was inhibited with anti-CCL17 monoclonal antibodies.

  6. TSLP (show TSLP Proteins) activated a subset of CD11b (show ITGAM Proteins)(+) DCs in the skin to produce CCL17, upregulate CCR7 (show CCR7 Proteins), and migrate to the draining lymph node to initiate Th2 differentiation.

  7. CCL17 is required for induction of intestinal inflammation in mice and has an autocrine effect on dendritic cells that promotes production of inflammatory cytokines and activation of Th1 (show HAND1 Proteins) and Th17 cells and reduces expansion of Treg cells.

  8. Kinetics of CCL17 mRNA expression in an allergic contact dermatitis model.

  9. Thymus and activation-regulated chemokine (TARC)/CC chemokine (show CCL1 Proteins) ligand (CCL) 17 accelerates wound healing by enhancing fibroblast migration.

  10. Data identify DC-derived CCL17 as a central regulator of Treg homeostasis, implicate DCs and their effector functions in atherogenesis, and suggest that CCL17 might be a target for vascular therapy.

CCL17 Protein Profile

Protein Summary

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Gene names and symbols associated with CCL17

  • chemokine (C-C motif) ligand 17 (CCL17)
  • chemokine (C-C motif) ligand 17 (Ccl17)
  • A-152E5.3 protein
  • Abcd-2 protein
  • CCL17 protein
  • Scya17 protein
  • Scya17l protein
  • Tarc protein

Protein level used designations for CCL17

chemokine (C-C motif) ligand 17 , C-C motif chemokine 17 , CC chemokine TARC , T cell-directed CC chemokine , small inducible cytokine subfamily A (Cys-Cys), member 17 , small-inducible cytokine A17 , thymus and activation-regulated chemokine , small inducible cytokine subfamily A17 , chemokine ligand 17-like protein , chemokine CCL17/TARC , small inducible cytokine A17

GENE ID SPECIES
467985 Pan troglodytes
6361 Homo sapiens
20295 Mus musculus
493832 Felis catus
100140488 Bos taurus
403586 Canis lupus familiaris
415652 Gallus gallus
100715805 Cavia porcellus
780408 Sus scrofa
117518 Rattus norvegicus
101120186 Ovis aries
574180 Macaca mulatta
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