anti-Chemokine (C-C Motif) Receptor 4 (CCR4) Antibodies

The protein encoded by CCR4 belongs to the G-protein-coupled receptor family . Additionally we are shipping CCR4 Kits (25) and CCR4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCR4 104625 Q8K3P5
CCR4 287249 Q6AXU9
CCR4 1233 P51679
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Top anti-CCR4 Antibodies at antibodies-online.com

Showing 10 out of 212 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-CCR4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Fluorescein FACS Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human/Rat CCR4 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse PE FACS Detection of CCR4 in Rat Peripheral Blood Cells by Flow Cytometry. Rat peripheral blood cells were stained with Mouse Anti-Human/Rat CCR4 PE-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse Allophycocyanin FACS Detection of CCR4 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Mouse Anti-Human/Rat CCR4 APC-conjugated Monoclonal Antibody. Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$140.70
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody. Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$309.75
Details
Cow Rabbit Un-conjugated WB Western blot analysis of CCR4 expression in HL60 (A), MCF7 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Dog Rabbit Un-conjugated WB Western blot analysis of CCR4 expression in HEK293T (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat exfoliated cells tissue labeled with Anti-CCR4 Polyclonal Antibody, Unconjugated (ABIN738666) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat cells labeled with Anti-CCR4/CD194 Polyclonal Antibody, Unconjugated (ABIN738666) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Dog Rabbit Un-conjugated WB Western blot analysis of CCR4 using Jurkat cell lysates. 100 μg Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated WB Western Blot: CCR4 Antibody [ABIN42890606] - analysis of CCR4 in A) Daudi and B) NIH 3T3 cell lysate using this antibody. 0.1 mg Log in to see 7 to 9 Days
$343.88
Details

CCR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CCR4 Antibodies

  1. Human Monoclonal CCR4 Primary Antibody for CyTOF, FACS - ABIN4899090 : Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2013 (PubMed)
    Show all 12 Pubmed References

  2. Human Monoclonal CCR4 Primary Antibody for CyTOF, FACS - ABIN4899091 : Zola, Swart, Banham, Barry, Beare, Bensussan, Boumsell, D Buckley, Bühring, Clark, Engel, Fox, Jin, Macardle, Malavasi, Mason, Stockinger, Yang: CD molecules 2006--human cell differentiation molecules. in Journal of immunological methods 2007 (PubMed)
    Show all 12 Pubmed References

  3. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895504 : Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer. in Journal of translational medicine 2014 (PubMed)
    Show all 11 Pubmed References

  4. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895505 : Muller, Sonkoly, Eulert, Gerber, Kubitza, Schirlau, Franken-Kunkel, Poremba, Snyderman, Klotz, Ruzicka, Bier, Zlotnik, Whiteside, Homey, Hoffmann: Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. in International journal of cancer 2006 (PubMed)
    Show all 11 Pubmed References

  5. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN2689051 : Bonecchi, Bianchi, Bordignon, DAmbrosio, Lang, Borsatti, Sozzani, Allavena, Gray, Mantovani, Sinigaglia: Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. in The Journal of experimental medicine 1998 (PubMed)
    Show all 9 Pubmed References

  6. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN2689052 : Campbell, Haraldsen, Pan, Rottman, Qin, Ponath, Andrew, Warnke, Ruffing, Kassam, Wu, Butcher: The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. in Nature 1999 (PubMed)
    Show all 7 Pubmed References

  7. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895501 : James, Gates, LaFond, Yamamoto, Ni, Mai, Gersuk, OBrien, Nguyen, Zeitner, Lanteri, Norris, Chaussabel, Malhotra, Kwok: Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome. in PLoS pathogens 2016 (PubMed)
    Show all 7 Pubmed References

  8. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895502 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 7 Pubmed References

  9. Human Polyclonal CCR4 Primary Antibody for ICC, FACS - ABIN152140 : Power, Meyer, Nemeth, Bacon, Hoogewerf, Proudfoot, Wells: Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. in The Journal of biological chemistry 1995 (PubMed)
    Show all 6 Pubmed References

  10. Human Monoclonal CCR4 Primary Antibody for FACS - ABIN4895497 : Antonelli, Mahnke, Hodge, Porter, Barber, DerSimonian, Greenwald, Roby, Mican, Sher, Roederer, Sereti: Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. in Blood 2010 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CCR4 Interaction Partners

Mouse (Murine) Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  2. CCR4 is critically involved in regional lymph node dendritic cell-Th17 cell interactions that are necessary for Th17 cell-mediated induction of antitumor CD8 (show CD8A Antibodies)+ effector T cells in mice bearing B16 melanoma.

  3. CCR4 is involved in immunosuppression after severe sepsis and suggest that CCR4+ Regulatory T Cells negatively modulate the short and long-term immune responses.

  4. CCL22 (show CCL22 Antibodies) was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells

  5. CCR4 is involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocytes

  6. results show that the IL-4 (show IL4 Antibodies)/CCL22 (show CCL22 Antibodies)/CCR4 axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators

  7. These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  8. that effective engagement of CCR4 by CCL17 (show CCL17 Antibodies) involves two distinct binding domains and interaction with both is required for signaling

  9. NF-kappaB (show NFKB1 Antibodies) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 might play a crucial role

  10. CCR4-expressing Th2cells play a critical role in the pathogenesis of bronchial asthma by producing Th2 cytokines.

Human Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. Chemokine (show CCL1 Antibodies) receptors CCR3 (show CCR3 Antibodies) and CCR4, and the mucosa specific chemokine (show CCL1 Antibodies) CCL28 (show ENC1 Antibodies) have predominant roles in oral wound healing by increasing human gingiva fibroblast proliferation, migration, and the secretion of IL-6 (show IL6 Antibodies) and HGF (show HGF Antibodies) and reducing the secretion of TIMP-1 (show TIMP1 Antibodies).

  2. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

  3. The percentage of CXCR3 (show CXCR3 Antibodies)(+) CD4 (show CD4 Antibodies)(+) TEM (show CYLD Antibodies) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (show SELPLG Antibodies)(+) CD4 (show CD4 Antibodies)(+) TCM cells expressing CCR6 (show CCR6 Antibodies)(+) or CCR4(+)CXCR3 (show CXCR3 Antibodies)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  4. Case Report: CCR4+ T-cell depletion by mogamulizumab treatment of adult T-cell leukaemia/lymphoma results in CD8 (show CD8A Antibodies)-positive T-cell mediated dermatitis.

  5. CCL22 (show CCL22 Antibodies)-specific antibodies reveal that engagement of two distinct binding domains on CCL22 (show CCL22 Antibodies) is required for CCR4-mediated function.

  6. CCR4 mutation is an important determinant of the clinical course in ATLL cases, and that NS and FS mutations of CCR4 behave differently with respect to ATLL pathophysiology.

  7. Distinctive Treg associated CCR4-CCL22 (show CCL22 Antibodies) expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (show DSG3 Antibodies).

  8. Data show that CCR4 was over-expressed in lymph node-negative human gastric cancer tissues and suggest its involvement in promoting tumor invasion probably, through up-regulation of MMP9 (show MMP9 Antibodies).

  9. CCR4 C1014T and CCL22 (show CCL22 Antibodies) C16A genetic variations were neither associated with the risk, nor with the progression of colorectal cancer in Iranian population

  10. Higher percentages of CCR4+ CD4 (show CD4 Antibodies) TEM (show CYLD Antibodies) cells in acute RSV infection were accompanied with higher percentages of CXCR3 (show CXCR3 Antibodies)+ CD8 (show CD8A Antibodies) TEM (show CYLD Antibodies) cells, whereas the development of long-lived memory CXCR3 (show CXCR3 Antibodies)+ CD4 (show CD4 Antibodies) and CD8 (show CD8A Antibodies) TCM cells seems to be compromised

CCR4 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene names and symbols associated with CCR4

  • chemokine (C-C motif) receptor 4 (CCR4) antibody
  • CCR4-NOT transcription complex, subunit 6 (Cnot6) antibody
  • chemokine (C-C motif) receptor 4 (Ccr4) antibody
  • A230103N10Rik antibody
  • AA407540 antibody
  • AW456442 antibody
  • C-C CKR-4 antibody
  • CC-CKR-4 antibody
  • CCR4 antibody
  • CD194 antibody
  • CHEMR1 antibody
  • ChemR13 antibody
  • CKR4 antibody
  • Cmkbr4 antibody
  • HGCN:14099 antibody
  • K5-5 antibody
  • LESTR antibody
  • RGD1310783 antibody
  • Sdf1r antibody

Protein level used designations for CCR4

chemokine (C-C motif) receptor 4 , C-C chemokine receptor type 4-like , c-C chemokine receptor type 4-like , CCR4-NOT transcription complex subunit 6 , carbon catabolite repressor protein 4 homolog , cytoplasmic deadenylase , C-C CKR-4 , C-C chemokine receptor type 4 , CCR-4 , chemokine (C-C) receptor 4 , CC chemokine receptor 4 , CC-CKR-4 , fusin , leukocyte-expressed seven-transmembrane-domain receptor , C-C chemokine receptor 4

GENE ID SPECIES
100397096 Callithrix jacchus
100445664 Pongo abelii
100585668 Nomascus leucogenys
104625 Mus musculus
287249 Rattus norvegicus
1233 Homo sapiens
403541 Canis lupus familiaris
408019 Bos taurus
12773 Mus musculus
171054 Rattus norvegicus
Selected quality suppliers for anti-CCR4 (CCR4) Antibodies
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