Chemokine (C-X-C Motif) Ligand 10 Proteins (CXCL10)

CXCL10 encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Additionally we are shipping CXCL10 Antibodies (341) and CXCL10 Kits (122) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CXCL10 3627 P02778
CXCL10 15945 P17515
CXCL10 245920 P48973
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Top CXCL10 Proteins at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$206.55
Details
HOST_Escherichia coli (E. coli) Cow His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$845.00
Details
HOST_Escherichia coli (E. coli) Human His tag Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Dog His tag 100 μg Log in to see 15 to 18 Days
$1,280.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$103.27
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 20 to 21 Days
$437.80
Details

CXCL10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , ,
Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced CXCL10 Proteins

  1. Human CXCL10 Protein expressed in Escherichia coli (E. coli) - ABIN1305104 : Farber: Mig and IP-10: CXC chemokines that target lymphocytes. in Journal of leukocyte biology 1997 (PubMed)
    Show all 4 Pubmed References

More Proteins for Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaction Partners

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

  2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 (show CCL2 Proteins) mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR (show MYLIP Proteins)-21.

  4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

  5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. IL-27 (show IL27 Proteins) stimulation activated STAT1 (show STAT1 Proteins) and STAT3 (show STAT3 Proteins) in HeLa and T98G cells, suggesting that IL-27 (show IL27 Proteins) engages the STAT1 (show STAT1 Proteins)/3 pathway, which then leads to the upregulation of IL-6 (show IL6 Proteins), IP-10, and MIG (show CXCL9 Proteins)

  2. Data suggest that, unlike non-metastatic intestinal epithelial cells (IECs), metastatic IECs express TLR3 (show TLR3 Proteins) and that TLR3 (show TLR3 Proteins) agonists induce inflammatory cytokine (CXCL10) production and promote invasiveness of IECs. (TLR3 (show TLR3 Proteins) = toll-like receptor 3 (show TLR3 Proteins); CXCL10 = chemokine (show CCL1 Proteins) [C-X-C motif] ligand 10 protein)

  3. Studied perinatally HIV-infected children on cART and in good clinical status with respect to HIV disease; found that high plasma levels of Interferon-gamma-inducible protein 10 (IP10) associate with increased numbers of abnormal memory B cells (MBCs) phenotypes. IP10 appears to be a sensitive marker to predict the presence of exhausted MBC.

  4. These data suggest that elevated IP-10 levels may impair NK cell function during HIV infection and that IP-10/CXCR3 (show CXCR3 Proteins) blocking may be a novel therapeutic strategy in the control and functional cure of HIV.

  5. Results provide evidence for an association between an increase level of CCL21 (show CCL21 Proteins) and IP-10 in the blood and pulmonary involvement in systemic lupus erythematosus patients.

  6. findings show that S. aureus downregulates superantigen-induced IP-10 production and prevents Th1 (show TH1L Proteins) cell recruitment; S. aureus triggered activation of MAPKs p38 (show CRK Proteins) and ERK (show EPHB2 Proteins), as well as inhibition of STAT1 (show STAT1 Proteins) signaling in monocytes, altogether contributing to the downregulation of IP-10

  7. Mothers of children affected by autoimmune congenital heart block did not have significantly elevated levels of IP-10 expression.

  8. results indicate that rhinovirus (RV) stimulates CXCL-10 expression via the IL-33 (show IL33 Proteins)/ST2 (show SULT2A1 Proteins) signaling axis, and that TLR2 signaling limits RV-induced CXCL-10 via IRAK-1 (show IRAK1 Proteins) depletion at least in airway epithelial cells

  9. This would suggest that the change in IP-10 is genotypically driven, while the change in IL-6 (show IL6 Proteins) may be reflective of systemic lupus erythematosus (SLE) transition status. These data suggest that IFIH1 (show IFIH1 Proteins) may contribute to SLE pathogenesis via altered inflammatory mechanisms.

  10. HCV infection leads to upregulated expression of CXCL10 in brain microvascular endothelial cells, which is probably via the phosphorylation of NF-kappaB (show NFKB1 Proteins).

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10/CXCR3 (show CXCR3 Proteins) axis

  2. CXCL10 chemokine (show CCL1 Proteins) levels correlate negatively with gremlin-1 (show GREM1 Proteins) levels in mouse and human lung.

  3. Increased CXCL10 expression led to decreased tumour burden and malignant ascites accumulation in the ID8 syngeneic murine model of HGSC.

  4. These findings demonstrate that the CXCL10/CXCR3 (show CXCR3 Proteins) chemokine (show CCL1 Proteins) pathway is critical in shaping CD8 (show CD8A Proteins)(+) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and disease.

  5. CXCL10 plays in the pathogenesis of recurrent Herpetic stromal keratitis, and that CXCL9 (show CXCL9 Proteins) displays its importance when CXCL10 is absent.

  6. PERK (show EIF2AK3 Proteins) and IRE1alpha (show ERN1 Proteins)/XBP1 (show XBP1 Proteins) in the unfolded protein response differentially regulate the expression of CXCL10 and CCL2 (show CCL2 Proteins) likely through modulation of ER stress-induced NF-kappaB (show NFKB1 Proteins) RelA (show NFkBP65 Proteins) and STAT3 (show STAT3 Proteins) activation.

  7. CXCL10 might influence the cellular composition locally in the islet graft, thereby playing a role in the autoimmune destruction. CXCL10 might therefore constitute a potential therapeutic target to prolong islet graft survival

  8. Data provide first evidence for a link between oncogenic JAK2V617F signaling and cell intrinsic induction of CXCL10 induced by activated NFkB signaling.

  9. Genome-wide expression of isolated Kupffer cells following pressure-controlled hemorrhage revealed a significant increase of gene expression of Cxcl10, Il4ra, Csf2rb2, Lcn2, and Gbp5, which might represent new biomarkers for early diagnosis of post-traumatic complications.

  10. Donor interleukin-22 (show IL22 Proteins) and host type I interferon (show IFNA Proteins) signaling pathway participate in intestinal graft-versus-host disease via STAT1 (show STAT1 Proteins) activation and CXCL10.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF (show CSF2 Proteins) gene transcription.

  2. IL-17A (show IL17A Proteins) was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.

CXCL10 Protein Profile

Protein Summary

This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Gene names and symbols associated with CXCL10

  • chemokine (C-X-C motif) ligand 10 (CXCL10)
  • C-X-C motif chemokine 10 (cxl10)
  • chemokine (C-X-C motif) ligand 10 (Cxcl10)
  • C7 protein
  • CRG-2 protein
  • CXCL10 protein
  • gIP-10 protein
  • Ifi10 protein
  • INP10 protein
  • IP-10 protein
  • IP10 protein
  • mob-1 protein
  • Scyb10 protein

Protein level used designations for CXCL10

chemokine (C-X-C motif) ligand 10 , C-X-C motif chemokine 10 , chemokine CXC-like protein , chemokine C-X-C motif ligand 10 , C-X-C motif chemokine 10-like protein , 10 kDa interferon gamma-induced protein , gamma IP10 , gamma-IP10 , interferon-inducible cytokine IP-10 , protein 10 from interferon (gamma)-induced cell line , small inducible cytokine subfamily B (Cys-X-Cys), member 10 , small-inducible cytokine B10 , interferon activated gene 10 , interferon-gamma induced protein CRG-2 , interferon-gamma-induced protein CRG-2 , small inducible cytokine B subfamily (Cys-X-Cys), member 10 , interferon-inducible protein 10 , protein Mob-1 , small inducible cytokine B subfamily (Cys-X-Cys) member 10 , gamma interferon inducible protein 10 , CXC chemokine ligand 10 , interferon-gamma-inducible protein 10 , interferon-gamma-inducible protein-10 , 10 kDa interferon-gamma-induced protein , 10 kDa interferon-gamma-inducible protein CXCL10 , IP-10 , small inducible cytokine B10

GENE ID SPECIES
461242 Pan troglodytes
494019 Sus scrofa
100050993 Equus caballus
100195999 Salmo salar
3627 Homo sapiens
15945 Mus musculus
245920 Rattus norvegicus
615107 Bos taurus
478432 Canis lupus familiaris
442997 Ovis aries
574243 Macaca mulatta
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