anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) Antibodies

CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Kits (50) and CXCR3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR3 2833 P49682
CXCR3 84475 Q9JII9
CXCR3 12766 O88410
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Top anti-CXCR3 Antibodies at antibodies-online.com

Showing 10 out of 295 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB CXCR3 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CXCR3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CXCR3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells, using CXCR3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat exfoliated cells labeled with Anti-CXCR3 Polyclonal Antibody, Unconjugated (ABIN678653) at 1:200 followed by conjugation to the secondary antibody and DAB staining HCCLM3 cells probed with Rabbit Anti-CXCR3 Polyclonal Antibody, Unconjugated  ) at 1:100 for 30 minutes followed by incubation with a conjugated secondary -FITC) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Fluorescein FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 Fluorescein-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$121.80
Details
Human Mouse Allophycocyanin FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 APC-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse PerCP FACS Detection of CXCR3 in Human Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PerCP-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PerCP-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse PE FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse Un-conjugated FACS, IHC, Neut Chemotaxis Induced by CXCL11/I-TAC and Neutralization by Human CXCR3 Antibody. Recombinant Human CXCL11/I-TAC. The ND50 is typically 0.3-1.5 ug/mL. CXCR3 in Human Tonsil. CXCR3 was detected in immersion fixed paraffin-embedded sections of human tonsil using Human CXCR3 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$296.10
Details
Mouse Rat Allophycocyanin FACS Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE-conjugated Monoclonal Antibody. Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$112.35
Details
Mouse Rat Alexa Fluor 488 FACS Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD4 APC-conjugated Monoclonal Antibody. Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD4 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$112.35
Details

CXCR3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CXCR3 Antibodies

  1. Human Monoclonal CXCR3 Primary Antibody for FACS, IHC - ABIN4899102 : Falk, Singh, Faber, Nissen, Hviid, Sørensen: Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration. in Investigative ophthalmology & visual science 2014 (PubMed)
    Show all 30 references for 4899102

  2. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895563 : Clay, Rodrigues, Harvey, Leutenegger, Esser: Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques. in Journal of virology 2005 (PubMed)
    Show all 19 references for 4895563

  3. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895557 : Chihara, Aranami, Oki, Matsuoka, Nakamura, Kishida, Yokoyama, Kuroiwa, Hattori, Okamoto, Murata, Toda, Miyake, Yamamura: Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica. in PLoS ONE 2013 (PubMed)
    Show all 19 references for 4895557

  4. Human Polyclonal CXCR3 Primary Antibody for FACS, IF (p) - ABIN678653 : Zhang, Fei, Gao, Liu, Zhang: The role of CXCR3 in the induction of primary biliary cirrhosis. in Clinical & developmental immunology 2011 (PubMed)
    Show all 5 references for 678653

  5. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895543 : Mackay, Rahimpour, Ma, Collins, Stock, Hafon, Vega-Ramos, Lauzurica, Mueller, Stefanovic, Tscharke, Heath, Inouye, Carbone, Gebhardt: The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. in Nature immunology 2013 (PubMed)
    Show all 4 references for 4895543

  6. Human Polyclonal CXCR3 Primary Antibody for EIA, FACS - ABIN951214 : Zhou, Tang, Qin, Gayed, Li, Skokos, Kyriakides, Pober, Tellides: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. in The Journal of experimental medicine 2010 (PubMed)
    Show all 4 references for 951214

  7. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895547 : Funakoshi, Shimizu, Numata, Ato, Melchers, Ohnishi: BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. in PLoS ONE 2015 (PubMed)

  8. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895553 : Tha-In, Metselaar, Tilanus, Groothuismink, Kuipers, de Man, Kwekkeboom: Intravenous immunoglobulins suppress T-cell priming by modulating the bidirectional interaction between dendritic cells and natural killer cells. in Blood 2007 (PubMed)

  9. Human Polyclonal CXCR3 Primary Antibody for ELISA, WB - ABIN1535574 : Marchese, Heiber, Nguyen, Heng, Saldivia, Cheng, Murphy, Tsui, Shi, Gregor: Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. in Genomics 1996 (PubMed)

  10. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895555 : de-Oliveira-Pinto, Marinho, Povoa, de Azeredo, de Souza, Barbosa, Motta-Castro, Alves, Ávila, de Souza, da Cunha, Damasco, Paes, Kubelka: Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever. in PLoS ONE 2012 (PubMed)

More Antibodies against CXCR3 Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. These data suggest that elevated IP-10 (show CXCL10 Antibodies) levels may impair NK cell function during HIV infection and that IP-10 (show CXCL10 Antibodies)/CXCR3 blocking may be a novel therapeutic strategy in the control and functional cure of HIV.

  2. Our result showed that CXCR2 (show CXCR2 Antibodies) expression was correlated with high grade (P = 0.024), advanced stage (P = 0.029) and metastasis (P = 0.018). The log-rank test revealed that high CXCR2 (show CXCR2 Antibodies) and CXCR3 expressions are related to poorer overall survival (P < 0.001; P < 0.001).

  3. The percentage of CXCR3(+) CD4 (show CD4 Antibodies)(+) TEM (show CYLD Antibodies) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (show SELPLG Antibodies)(+) CD4 (show CD4 Antibodies)(+) TCM cells expressing CCR6 (show CCR6 Antibodies)(+) or CCR4 (show CCR4 Antibodies)(+)CXCR3(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  4. Our studies suggest that CXCR3 is a key contributor to the pathogenesis of Alopecia areata by mediating the infiltration of autoreactive CD8 (show CD8A Antibodies)+NKG2D (show KLRK1 Antibodies)+ T cells into the skin

  5. TNF-alpha (show TNF Antibodies) augments CXCR2 (show CXCR2 Antibodies) and CXCR3 to promote the progression of renal cell carcinoma (show MOK Antibodies) leading to a poor prognosis.

  6. TLR9 (show TLR9 Antibodies) ligands may contribute to the immunopathogenesis of sarcoidosis via induction of CXCL10 (show CXCL10 Antibodies) release in the alveolar macrophages.

  7. The CXCL10 (show CXCL10 Antibodies)/CXCR3 axis mediates T-cell recruitment into the skin in progressive vitiligo (show MITF Antibodies). Blocking this chemotactic mechanism may present a new form of therapy.

  8. IP-10 (show CXCL10 Antibodies) complexes with CXCR3, which in turn activates the ERK1/2 (show MAPK1/3 Antibodies) pathway, thus resulting in upregulation of p-CREB (show CREB1 Antibodies) and increased vascular smooth muscle cell proliferation.

  9. the CXCR3+/CCR5 (show CCR5 PLURAL_@2304@)+ expression was higher in the neoplastic as compared to the hyperplastic nodules.

  10. monocytes and lymphocytes cooperate to enhance migration towards CXCR3 chemokines and CCL5 (show CCL5 Antibodies) in COPD (show ARCN1 Antibodies)

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. These results demonstrate a critical role for both BLT1 and CXCR3 in cytotoxic T lymphocyte (CTL) migration to tumors and thus may be targeted to enhance efficacy of CTL-based immunotherapies.

  2. Our studies suggest that CXCR3 is a key contributor to the pathogenesis of Alopecia areata by mediating the infiltration of autoreactive CD8 (show CD8A Antibodies)+NKG2D (show KLRK1 Antibodies)+ T cells into the skin

  3. Cxcr3 is up-regulated by DNA demethylation and interaction with C/EBPalpha (show CEBPA Antibodies) which contributes to neuropathic pain.

  4. These findings demonstrate that the CXCL10 (show CXCL10 Antibodies)/CXCR3 chemokine (show CCL1 Antibodies) pathway is critical in shaping CD8 (show CD8A Antibodies)(+) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and disease.

  5. this study shows that although T cell-specific expression of CXCR3 promotes the accumulation of CXCR3-expressing T cells during Leishmania donovani infection, this does not enhance resistance to visceral leishmaniasis; hepatic granuloma formation is impaired in CXCR3 transgenic mice

  6. beta4GalT1 can regulate N-glycans of CXCR3 in RA. N-glycans of CXCR3 affects CXCL10 (show CXCL10 Antibodies)/CXCR3 ligand-binding which enhancing fibroblast-like synoviocytes invasion.

  7. this study shows that diosgenin-mediated anti-allergic effects are associated with increased number of Foxp3 (show FOXP3 Antibodies)+ Treg cells expressing CXCR3

  8. Circulating levels of chemokines that activate CXCR3 are elevated in non-obese diabetic (NOD) mice, consistent with clinical findings in human diabetes.

  9. CXCR3 interacts with IL-10 (show IL10 Antibodies) secreted by CD8 (show CD8A Antibodies)+CD122 (show IL2RB Antibodies)+ regulatory T cells in a mouse model of Acute Lung Injury and promotes interferon-gamma (show IFNG Antibodies) and CXCL10 (show CXCL10 Antibodies) release.

  10. This study demonstrates a previously unrecognized role of CXCR3 signaling in glial cells in negatively regulating Th17 cell expansion during experimental autoimmune encephalomyelitis

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression

CXCR3 Antigen Profile

Protein Summary

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene names and symbols associated with CXCR3

  • chemokine (C-X-C motif) receptor 3 (CXCR3) antibody
  • chemokine (C-X-C motif) receptor 3 (cxcr3) antibody
  • chemokine (C-X-C motif) receptor 3 (Cxcr3) antibody
  • CD182 antibody
  • Cd183 antibody
  • CKR-L2 antibody
  • Cmkar3 antibody
  • CXC-R3 antibody
  • CXCR-3 antibody
  • cxcr3 antibody
  • Gpr9 antibody
  • IP10-R antibody
  • Mig-R antibody
  • MigR antibody

Protein level used designations for CXCR3

chemokine (C-X-C motif) receptor 3 , C-X-C chemokine receptor type 3 , CXC-R3 , CXCR-3 , G protein-coupled receptor 9 , IP-10 receptor , IP10 receptor , Mig receptor , chemokine (C-X-C) receptor 3 , interferon-inducible protein 10 receptor , CXC chemokine receptor 3 , Interferon-inducible protein 10 receptor

GENE ID SPECIES
465704 Pan troglodytes
496477 Xenopus (Silurana) tropicalis
699438 Macaca mulatta
2833 Homo sapiens
84475 Rattus norvegicus
12766 Mus musculus
497018 Bos taurus
491952 Canis lupus familiaris
100860874 Capra hircus
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