anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) Antibodies

CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Additionally we are shipping CXCR3 Kits (53) and CXCR3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR3 2833 P49682
CXCR3 84475 Q9JII9
CXCR3 12766 O88410
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Top anti-CXCR3 Antibodies at antibodies-online.com

Showing 10 out of 339 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562 cells, using CXCR3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC, Neut Chemotaxis Induced by CXCL11/I-TAC and Neutralization by Human CXCR3 Antibody. Recombinant Human CXCL11/I-TAC. The ND50 is typically 0.3-1.5 ug/mL. CXCR3 in Human Tonsil. CXCR3 was detected in immersion fixed paraffin-embedded sections of human tonsil using Human CXCR3 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$296.10
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CXCR3 Picoband antibody,  IHC(P): Human Lung Cancer Tissue Anti-CXCR3 Picoband antibody,  All lanes: Anti-CXCR3 at 0.5ug/ml Lane 1: Colo320 Whole Cell Lysate at 40ug Lane 2: SGC Whole Cell Lysate at 40ug Predicted bind size: 41KD Observed bind size: 41KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$221.76
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB CXCR3 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CXCR3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CXCR3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rat Un-conjugated CyTOF, FACS Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody. Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$266.70
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat exfoliated cells labeled with Anti-CXCR3 Polyclonal Antibody, Unconjugated (ABIN678653) at 1:200 followed by conjugation to the secondary antibody and DAB staining HCCLM3 cells probed with Rabbit Anti-CXCR3 Polyclonal Antibody, Unconjugated  ) at 1:100 for 30 minutes followed by incubation with a conjugated secondary -FITC) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Fluorescein FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 Fluorescein-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$121.80
Details
Human Mouse Allophycocyanin FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 APC-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse PE FACS Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody. Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details

CXCR3 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CXCR3 Antibodies

  1. Human Monoclonal CXCR3 Primary Antibody for CyTOF, FACS - ABIN4899102 : Falk, Singh, Faber, Nissen, Hviid, Sørensen: Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration. in Investigative ophthalmology & visual science 2014 (PubMed)
    Show all 30 Pubmed References

  2. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895557 : Chihara, Aranami, Oki, Matsuoka, Nakamura, Kishida, Yokoyama, Kuroiwa, Hattori, Okamoto, Murata, Toda, Miyake, Yamamura: Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica. in PLoS ONE 2013 (PubMed)
    Show all 19 Pubmed References

  3. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895558 : Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 19 Pubmed References

  4. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895563 : Clay, Rodrigues, Harvey, Leutenegger, Esser: Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques. in Journal of virology 2005 (PubMed)
    Show all 19 Pubmed References

  5. Human Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895564 : Hosomi, Oshitani, Kamata, Sogawa, Okazaki, Tanigawa, Yamagami, Watanabe, Tominaga, Watanabe, Fujiwara, Maeda, Hirakawa, Arakawa: Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. in Clinical and experimental immunology 2011 (PubMed)
    Show all 19 Pubmed References

  6. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895552 : Christensen, de Lemos, Moos, Christensen, Thomsen: CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 9 Pubmed References

  7. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895551 : Horikawa, Fujimoto, Hasegawa, Matsushita, Hamaguchi, Kawasuji, Matsushita, Fujita, Ogawa, Takehara, Steeber, Sato: E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis. in The American journal of pathology 2006 (PubMed)
    Show all 9 Pubmed References

  8. Human Polyclonal CXCR3 Primary Antibody for FACS, IF (p) - ABIN678653 : Zhang, Fei, Gao, Liu, Zhang: The role of CXCR3 in the induction of primary biliary cirrhosis. in Clinical & developmental immunology 2011 (PubMed)
    Show all 5 Pubmed References

  9. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895544 : Angkasekwinai, Sringkarin, Supasorn, Fungkrajai, Wang, Chayakulkeeree, Ngamskulrungroj, Angkasekwinai, Pattanapanyasat: Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts. in Infection and immunity 2014 (PubMed)
    Show all 4 Pubmed References

  10. Mouse (Murine) Monoclonal CXCR3 Primary Antibody for FACS - ABIN4895543 : Mackay, Rahimpour, Ma, Collins, Stock, Hafon, Vega-Ramos, Lauzurica, Mueller, Stefanovic, Tscharke, Heath, Inouye, Carbone, Gebhardt: The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. in Nature immunology 2013 (PubMed)
    Show all 4 Pubmed References

More Antibodies against CXCR3 Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. approach has been able to describe the structural events which dynamically characterize the molecular mechanisms involved in the binding of CXCR3 to CXCL11 (show CXCL11 Antibodies) and the critical role exerted by its N-terminal region in "hunting" and capturing the ligand.

  2. High CXCR3 expression is associated with chronic lymphocytic leukaemia in comparison to small lymphocytic lymphoma.

  3. CD4(+)CXCR3(+) T cells are h (show LY75 Antibodies)ighly enriched in the inflamed mucosa (show IL10 Antibodies) of intestinal bowel disease patients.

  4. CCL27 (show CCL27 Antibodies) drives baseline recruitment of Herpes simplex virus-specific CD8 (show CD8A Antibodies) T cells expressing CCR10 (show CCR10 Antibodies), while interferon (show IFNA Antibodies)-responsive CXCR3 ligands recruit additional cells in response to virus-driven inflammation.

  5. Up-regulation of CXCR3 chemokine (show CCL1 Antibodies) and its ligands in bronchoalveolar lavage fluid during organizing pneumonia increases the risk of chronic lung allograft dysfunction after lung transplantation.

  6. These data suggest that elevated IP-10 (show CXCL10 Antibodies) levels may impair NK cell function during HIV infection and that IP-10 (show CXCL10 Antibodies)/CXCR3 blocking may be a novel therapeutic strategy in the control and functional cure of HIV.

  7. Our result showed that CXCR2 (show CXCR2 Antibodies) expression was correlated with high grade (P = 0.024), advanced stage (P = 0.029) and metastasis (P = 0.018). The log-rank test revealed that high CXCR2 (show CXCR2 Antibodies) and CXCR3 expressions are related to poorer overall survival (P < 0.001; P < 0.001).

  8. The percentage of CXCR3(+) CD4 (show CD4 Antibodies)(+) TEM (show CYLD Antibodies) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (show SELPLG Antibodies)(+) CD4 (show CD4 Antibodies)(+) TCM cells expressing CCR6 (show CCR6 Antibodies)(+) or CCR4 (show CCR4 Antibodies)(+)CXCR3(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  9. Our studies suggest that CXCR3 is a key contributor to the pathogenesis of Alopecia areata by mediating the infiltration of autoreactive CD8 (show CD8A Antibodies)+NKG2D (show KLRK1 Antibodies)+ T cells into the skin

  10. TNF-alpha (show TNF Antibodies) augments CXCR2 (show CXCR2 Antibodies) and CXCR3 to promote the progression of renal cell carcinoma (show MOK Antibodies) leading to a poor prognosis.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Data suggest that the CXCL9 (show CXCL9 Antibodies)-CXCR3 axis plays a pivotal role in the liver-specific distribution of TRAIL+ NK cells in mice.

  2. ATF3 (show ATF3 Antibodies)-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10 (show CXCL10 Antibodies)-CXCR3 axis at multiple levels.

  3. study thus shows that lung mucosal-resident memory T cells are not generated following systemic TB immunization and that local inflammation is required for systemically activated T cells to home to lung mucosa, which is mediated by interaction between CXCR3 upregulated in these cells and its ligands IP-10 (show CXCL10 Antibodies) and MIG (show CXCL9 Antibodies)

  4. Antigen targeting to DEC-205 (show LY75 Antibodies) on dendritic cells leads to an IL-10 (show IL10 Antibodies)-dependent downregulation of CXCR3 expression on differentiated antigen-specific Th1 (show HAND1 Antibodies) cells in vivo. This downregulation interferes with the migration of Th1 (show HAND1 Antibodies) cells into the gut (show GUSB Antibodies) and protects mice against severe acute and relapsing intestinal inflammation.

  5. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10 (show CXCL10 Antibodies)/CXCR3 axis

  6. These results demonstrate a critical role for both BLT1 and CXCR3 in cytotoxic T lymphocyte (CTL) migration to tumors and thus may be targeted to enhance efficacy of CTL-based immunotherapies.

  7. Our studies suggest that CXCR3 is a key contributor to the pathogenesis of Alopecia areata by mediating the infiltration of autoreactive CD8 (show CD8A Antibodies)+NKG2D (show KLRK1 Antibodies)+ T cells into the skin

  8. Cxcr3 is up-regulated by DNA demethylation and interaction with C/EBPalpha (show CEBPA Antibodies) which contributes to neuropathic pain.

  9. These findings demonstrate that the CXCL10 (show CXCL10 Antibodies)/CXCR3 chemokine (show CCL1 Antibodies) pathway is critical in shaping CD8 (show CD8A Antibodies)(+) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and disease.

  10. this study shows that although T cell-specific expression of CXCR3 promotes the accumulation of CXCR3-expressing T cells during Leishmania donovani infection, this does not enhance resistance to visceral leishmaniasis; hepatic granuloma formation is impaired in CXCR3 transgenic mice

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 3 (CXCR3) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CXCR3 expression

CXCR3 Antigen Profile

Protein Summary

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Gene names and symbols associated with CXCR3

  • C-X-C motif chemokine receptor 3 (CXCR3) antibody
  • chemokine (C-X-C motif) receptor 3 (cxcr3) antibody
  • C-X-C motif chemokine receptor 3 (Cxcr3) antibody
  • chemokine (C-X-C motif) receptor 3 (Cxcr3) antibody
  • CD182 antibody
  • Cd183 antibody
  • CKR-L2 antibody
  • Cmkar3 antibody
  • CXC-R3 antibody
  • CXCR-3 antibody
  • cxcr3 antibody
  • Gpr9 antibody
  • IP10-R antibody
  • Mig-R antibody
  • MigR antibody

Protein level used designations for CXCR3

chemokine (C-X-C motif) receptor 3 , C-X-C chemokine receptor type 3 , CXC-R3 , CXCR-3 , G protein-coupled receptor 9 , IP-10 receptor , IP10 receptor , Mig receptor , chemokine (C-X-C) receptor 3 , interferon-inducible protein 10 receptor , CXC chemokine receptor 3 , Interferon-inducible protein 10 receptor

GENE ID SPECIES
465704 Pan troglodytes
496477 Xenopus (Silurana) tropicalis
699438 Macaca mulatta
2833 Homo sapiens
84475 Rattus norvegicus
12766 Mus musculus
497018 Bos taurus
491952 Canis lupus familiaris
100860874 Capra hircus
Selected quality suppliers for anti-CXCR3 (CXCR3) Antibodies
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