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The protein encoded by CHI3L2 is similar to bacterial chitinases but lacks chitinase activity. Additionally we are shipping Chitinase 3-Like 2 Antibodies (62) and Chitinase 3-Like 2 Proteins (7) and many more products for this protein.
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Human CHI3L2 ELISA Kit for Sandwich ELISA - ABIN1118144
Varghese, Sharma, Mishra, Vijayalakshmi, Harsha, Sathyaprabha, Bharath, Nalini, Alladi, Raju: Chitotriosidase - a putative biomarker for sporadic amyotrophic lateral sclerosis. in Clinical proteomics 2013
cerebrospinal fluid CHI3L1 (show CHI3L1 ELISA Kits) and CHI3L2 and serum CHI3L1 (show CHI3L1 ELISA Kits) might help to define multiple sclerosis disease stage
Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy.
YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis.
ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation.
human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40 (show CHI3L1 ELISA Kits)) is upregulated in osteoarthritic cartilage
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.
chitinase-3-like protein 2
, chondrocyte protein 39