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anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antibodies

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (57) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHI3L1 12654 Q61362
CHI3L1 1116 P36222
CHI3L1 89824 Q9WTV1
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Top anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB WB Suggested Anti-CHI3L1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$163.90
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extract of various cells, using CHI3L1 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Western blot analysis of YKL-40 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) HepG2 cells probed with Rabbit Anti-CHI3L1 Polyclonal Antibody  Alexa Fluor 488 Secondary 100 μL Log in to see 14 to 21 Days
$295.90
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
$357.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB CGP-39 staining of endometrium carcinoma. Paraffin-embedded human endometrium carcinoma tissue is stained with CGP-39 Antibody used at 1:300 dilution ON at 4°C. Tissue is fixed with 4% paraformaldehyde and antigen retrieval protocol consists in boiling for 15 min in 0.01M citrate buffer, pH6.0. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details

CHI3L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human , , , ,
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Rat (Rattus)


Top referenced anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies

  1. Human Monoclonal CHI3L1 Primary Antibody for EIA, IHC (p) - ABIN356240 : Bonneh-Barkay, Bissel, Wang, Fish, Nicholl, Darko, Medina-Flores, Murphey-Corb, Rajakumar, Nyaundi, Mellors, Bowser, Wiley: YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor. in The American journal of pathology 2008 (PubMed)
    Show all 2 references for ABIN356240

  2. Human Polyclonal CHI3L1 Primary Antibody for ELISA - ABIN1998531 : Rehli, Niller, Ammon, Langmann, Schwarzfischer, Andreesen, Krause: Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN1998531

  3. Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693 : Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008 (PubMed)

More Antibodies against Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Interaction Partners

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (show S100A9 Antibodies) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (show S100A9 Antibodies) receptor, RAGE (show AGER Antibodies) (Receptor for Advanced Glycation End products).

  2. IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  3. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  4. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  5. Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.

  6. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

  7. mechanism of BRP (show GDF5 Antibodies)-39 in bleomycin-induced pulmonary fibrosis

  8. Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis

  9. Data show that IL-1 (show IL1A Antibodies)-induced transcriptin factor RelB (show RELB Antibodies)/NF-kappa B p50 (show NFKB1 Antibodies) Subunit complex formation was further promoted by oncostatin M (show OSM Antibodies) and that these complexes directly bound to the secreted protein cartilage glycoprotein 39 (YKL-40) promoter.

  10. These results indicate that catalytically inactive BRP (show GDF5 Antibodies)-39 and Ym1 (show CHI3L3 Antibodies) are constitutive genes in normal mouse lung.

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. This is the first report on the association between low-frequency and common variants in the chitinases-related genes CHIA and CHI3L1 with the intensity of specific IgE to ABA-1 in a population naturally exposed to Ascaris and with Bet v 1 in a Swedish population.

  2. results indicate that patients with CHI3L1 rs880633 variant genotypes TC+CC are at a higher risk of HCC (show FAM126A Antibodies). CHI3L1 polymorphisms rs880633 or rs4950928 may be potential candidates for predicting poor HCC (show FAM126A Antibodies) prognosis and clinical status.

  3. High YKL-40 levels were associated with a 2-fold increased risk of venous thromboembolism, but the association was not causal.

  4. 83 preterm infants with Bronchopulmonary dysplasia born <28-wk gestation and still inpatients at 36-wk corrected age received an echocardiogram and blood tests of B-type natriuretic peptide (BNP (show BNP Antibodies)), troponin I, and YKL-40.

  5. Serum YKL-40 levels were increased in rheumatoid arthritis patients compared to controls. The highest levels were found in synovial fluid.

  6. this study shows that CHI3L1 levels in donor cells may be related to the risk of acute graft-versus-host disease and targeting CHI3L1 may be a promising clinical strategy to control acute graft-versus-host disease

  7. The study showed that serum YKL-40 levels were signi fi cantly elevated in patients with moderate and severe asthma compared with reference group. Although there was a positive correlation with disease severity, the study did not suggest serum YKL-40 to be a diagnostic marker of mild asthma as the difference in levels of serum YKL-40 between reference and mild asthma group was not found to be statistically signi fi cant.

  8. YKL-40 concentration in the serum of Kawasaki disease (KD) patients significantly increased during the acute disease phase compared with those of disease controls and healthy controls. Increased YKL-40 levels may provide a useful inflammatory marker for patients with KD

  9. CHI3L1 is associated with tumor metastasis and might be a prognostic biomarker for papillary thyroid carcinoma.

  10. YKL-40 expression was observed in 45 (58.4%) of 77 SVZ type II Glioblastomas (GBs (show GNB5 Antibodies)) and in 17 (22.6%) of 75 SVZ type III GBs (show GNB5 Antibodies)

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antigen Profile

Protein Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Gene names and symbols associated with CHI3L1

  • chitinase 3-like 1 (Chi3l1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (Chi3l1) antibody
  • ASRT7 antibody
  • AW208766 antibody
  • BP40 antibody
  • Brp39 antibody
  • CGP-39 antibody
  • Chil1 antibody
  • CLP-1 antibody
  • GP-39 antibody
  • GP38K antibody
  • GP39 antibody
  • HC-gp39 antibody
  • HCGP-3P antibody
  • hCGP-39 antibody
  • MGP-40 antibody
  • SPC-40 antibody
  • SPS-40 antibody
  • YKL-40 antibody
  • YKL40 antibody
  • YYL-40 antibody

Protein level used designations for CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPECIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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