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Cholecystokinin B Receptor Proteins (CCKBR)

CCKBR encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. Additionally we are shipping CCKBR Antibodies (82) and CCKBR Kits (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCKBR 887 P32239
Rat CCKBR CCKBR 25706 P30553
CCKBR 12426 P56481
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Top CCKBR Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

CCKBR Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Cholecystokinin B Receptor (CCKBR) Interaction Partners

Human Cholecystokinin B Receptor (CCKBR) interaction partners

  1. The neurotransmitter cholecystokinin (CCK (show CCK Proteins)), along with its receptors, CCKAR and CCKBR, have been previously associated with psychiatric disorders, suggesting that variants near these genes may play a role in the pre-pulse/startle response in this cohort

  2. There is functional synergy between cholecystokinin (show CCK Proteins) receptors CCKAR and CCKBR in mammalian brain development.

  3. CCK-BR SNP predicts survival and should be studied as a candidate genetic biomarker for those at risk of pancreatic cancer.

  4. treatment with gastrin (show GAST Proteins), a CCK2R agonist, stimulated the secretion of GLP-1 (show GCG Proteins), and that this effect was likely due to increased expression of proglucagon (show GCG Proteins) and PCSK1 (show PCSK1 Proteins) (also known as prohormone convertase 3 (PC3 (show PCSK1 Proteins) gene)).

  5. Our results indicate a promoting role of CCK2R on GIST tumourigenesis, particularly in tumours of gastric origin.

  6. The gastrin receptor is a promising tumor cell surface target for future prostate-cancer-specific imaging applications.

  7. DeltaFosB induction in prelimbic area occurred selectively in susceptible mice after chronic social defeat stress and produced these effects partly through induction of the cholecystokinin (CCK (show CCK Proteins))-B receptor.

  8. some CCKBR polymorphisms may contribute to an underlying predisposition towards suicidal behaviour in bipolar disorder.

  9. CCKBR and Bcl-2 (show BCL2 Proteins) were identified as targets of miR (show MLXIP Proteins)-148a.

  10. Gastric mucosal injury with H. pylori infection destroys the pH barrier on the foveolar epithelium and may induce gastrin receptor expression through pH changes.

Mouse (Murine) Cholecystokinin B Receptor (CCKBR) interaction partners

  1. CCKBR and D5R synergistically interact in the kidney, which may contribute to the maintenance of normal sodium balance following an increase in sodium intake

  2. findings provide novel evidence that Cnr1 (show CNR1 Proteins) contributes to cued fear expression via an interaction with the CCKB receptor.

  3. There is functional synergy between cholecystokinin (show CCK Proteins) receptors CCKAR and CCKBR in mammalian brain development.

  4. mice lacking CCK (show CCK Proteins) receptors exhibited a functional shift from the gastrin (show GAST Proteins)-CCK (show CCK Proteins) pathways to the neuronal pathway in control of the ECL (show APOC4 Proteins) cells and eventually the acid secretion

  5. CCK2R labels +4 antral stem cells that can be activated and expanded by progastrin, thus identifying one hormonal trigger for gastric stem cell interconversion and a potential target for gastric cancer chemoprevention and therapy.

  6. CCK-1 (show CCL28 Proteins) and -2 receptors may function synergistically in single PaPo neurons and deletion of CCK-1 (show CCL28 Proteins) receptors may facilitate CCK (show CCK Proteins)-2 receptor signaling.

  7. cholecystokinin receptor-2 has a role in stress-triggered fear memory and anxiety in the mouse

  8. shift of breakpoint on Arrhenius plot established in CCK (show CCK Proteins)(2) receptor-deficiency confirms that such kind of alteration in Na(+),K(+)-ATPase (show ATP1A1 Proteins) temperature dependence is likely related to the homeostatic adjustment of altered function of the sodium pump.

  9. Environmental enrichment has beneficial effects in neuropathic conditions and reinforce the causal link between CCK(2) receptors, mechanical sensitivity and the development of CCI-induced hypersensitivity.

  10. The gastrin receptor promotes pancreatic growth in transgenic mice.

CCKBR Protein Profile

Protein Summary

This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.

Gene names and symbols associated with CCKBR

  • cholecystokinin B receptor (CCKBR)
  • cholecystokinin B receptor (LOC100232835)
  • cholecystokinin B receptor (Cckbr)
  • CCK-B protein
  • CCK-BR protein
  • CCK-CHR protein
  • CCK2-R protein
  • Cck2r protein
  • CCKBR protein
  • CCKR-2 protein
  • Cholrec protein
  • GASR protein
  • LOC100232835 protein

Protein level used designations for CCKBR

cholecystokinin B receptor , gastrin/cholecystokinin type B receptor , CCK-B receptor , CCK-BR , CCK2 receptor , CCK2-R , cholecystokinin-2 receptor , gastrin receptor , CCK(B) receptor , CCK-B/gastrin receptor , CCK2/gastrin receptor , Cholecystokinin-2 receptor , gastrin , gastrin/CCK-B receptor , cholecystokinin receptor

GENE ID SPECIES
466414 Pan troglodytes
100055073 Equus caballus
100174772 Pongo abelii
100232835 Taeniopygia guttata
100595663 Nomascus leucogenys
887 Homo sapiens
25706 Rattus norvegicus
12426 Mus musculus
281665 Bos taurus
100328939 Oryctolagus cuniculus
100720322 Cavia porcellus
485333 Canis lupus familiaris
414885 Gallus gallus
101118381 Ovis aries
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