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CHRNA7 Proteins

(Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) CHRNA7 Protein (AA 25-129) (His-IF2DI Tag) (ABIN7122359)

CHRNA7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

CHRNA7 Protein (AA 318-469) (His tag) CHRNA7 Protein (AA 318-469) (His tag) CHRNA7 Protein (AA 318-469) (His tag) (ABIN3088463)

Crystallography grade CHRNA7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

CHRNA7 Protein (AA 23-230) (His tag) CHRNA7 Protein (AA 23-230) (His tag) CHRNA7 Protein (AA 23-230) (His tag) (ABIN3088462)

Crystallography grade CHRNA7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

CHRNA7 Proteins by Grade

Find CHRNA7 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CHRNA7 Proteins by Origin

Find CHRNA7 Proteins for a variety of species such as anti-Human CHRNA7, anti-Mouse CHRNA7, anti-Rat CHRNA7. The species listed below are among those available. Click on a link to go to the corresponding products.

CHRNA7 Proteins by Source

Here you will find CHRNA7 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CHRNA7 Proteins by Protein Type

Here you can find CHRNA7 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CHRNA7 Proteins by Application

Find CHRNA7 Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CHRNA7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122359
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088463
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088462
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134257
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134255
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113499
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134256
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN7508493
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413079
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424392
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750643
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our CHRNA7 Proteins

Chandley, Miller, Kwasigroch, Wilson, Miller: "Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia." in: Schizophrenia research, Vol. 109, Issue 1-3, pp. 98-101, (2009) (PubMed).

Aliases for CHRNA7 Proteins

cholinergic receptor nicotinic alpha 7 subunit (CHRNA7) Proteins
neuronal acetylcholine receptor subunit alpha-7 (LOC100374356) Proteins
cholinergic receptor, nicotinic, alpha 7 (neuronal) (chrna7) Proteins
cholinergic receptor, nicotinic, alpha polypeptide 7 (Chrna7) Proteins
cholinergic receptor nicotinic alpha 7 subunit (Chrna7) Proteins
cholinergic receptor, nicotinic, alpha 7 (CHRNA7) Proteins
neuronal acetylcholine receptor subunit alpha-7 (LOC100060521) Proteins
Acra7 Proteins
alpha7 Proteins
BTX Proteins
CHRNA7 Proteins
CHRNA7-2 Proteins
dZ70B1.1 Proteins
NACHRA7 Proteins
nAChRa7 Proteins
NARAD Proteins
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