anti-Cholinergic Receptor, Nicotinic, gamma (CHRNG) Antibodies

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Additionally we are shipping Cholinergic Receptor, Nicotinic, gamma Kits (12) and Cholinergic Receptor, Nicotinic, gamma Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHRNG 1146 P07510
CHRNG 25753 P18916
CHRNG 11449  
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Top anti-Cholinergic Receptor, Nicotinic, gamma Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB CHRNG Antibody (N-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHRNG antibody detected the CHRNG protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using CHRNG antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated FACS, IHC (fro), IP, IHC, WB   0.25 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated WB CHRNG antibody (70R-10544) used at 2.5 ug/ml to detect target protein. 50 μg Log in to see 6 to 8 Days
$473.93
Details
Human Mouse Un-conjugated FACS, IHC (fro), IP, WB   500 μL Log in to see 7 to 9 Days
$566.50
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

CHRNG Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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,
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Rat (Rattus)


Mouse (Murine)


Top referenced anti-Cholinergic Receptor, Nicotinic, gamma Antibodies

  1. Cow (Bovine) Polyclonal CHRNG Primary Antibody for WB - ABIN2774610 : Morgan, Brueton, Cox, Greally, Tolmie, Pasha, Aligianis, van Bokhoven, Marton, Al-Gazali, Morton, Oley, Johnson, Trembath, Brunner, Maher: Mutations in the embryonal subunit of the acetylcholine receptor (CHRNG) cause lethal and Escobar variants of multiple pterygium syndrome. in American journal of human genetics 2006 (PubMed)

More Antibodies against Cholinergic Receptor, Nicotinic, gamma Interaction Partners

Human Cholinergic Receptor, Nicotinic, gamma (CHRNG) interaction partners

  1. CHRNG mutations associated with interfamilial variability of the severity of the Escobar variant of multiple pterygium syndrome

  2. Two siblings with Escobar syndrome caused by homozygous mutations of the CHRNG gene were identified.

  3. Rare cases of congenital arthrogryposis multiplex caused by novel recurrent CHRNG mutations.

  4. No mutations were found in CHRNG, CHRND (show CHRND Antibodies) and CHRNA1 (show CHRNA1 Antibodies) genes of Indian families with Escobar syndrome.

  5. We did not identify a clear difference in mutation spectrum of the CHRNG gene between lethal form and non-lethal forms of multiple pterygium syndromes

  6. A good correlation was found between the expression of PAX3 (show PAX3 Antibodies)/7-FKHR (show FOXO1 Antibodies) and AChR, while MyoD1 (show MYOD1 Antibodies) was more sensitive but less specific.

  7. CHRNG mutations identified in families with Escobar syndrome show that the trait is a congenital dysmorphology caused by transient inactivation of the neuromuscular endplate.

  8. constructed and characterized four AChR gamma extracellular domain variants

  9. Detection of PAX3/7-FKHR fusion gene by one-step RT-PCR is useful in the diagnosis of rhabdomyosarcomas (RMS) and that AChR-gamma is overexpressed in Chinese RMS patients.

Mouse (Murine) Cholinergic Receptor, Nicotinic, gamma (CHRNG) interaction partners

  1. The presence of two new transcript variants (T1 and T2) of chrng expressed in mouse postnatal day 3 and adult skeletal muscles, is reported.

Cholinergic Receptor, Nicotinic, gamma (CHRNG) Antigen Profile

Protein Summary

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

Gene names and symbols associated with CHRNG

  • cholinergic receptor, nicotinic, gamma (muscle) (CHRNG) antibody
  • cholinergic receptor, nicotinic, gamma (muscle) (chrng) antibody
  • cholinergic receptor, nicotinic, gamma (CHRNG) antibody
  • cholinergic receptor, nicotinic, gamma (muscle) (Chrng) antibody
  • cholinergic receptor, nicotinic, gamma (chrng) antibody
  • cholinergic receptor, nicotinic, gamma polypeptide (Chrng) antibody
  • Achr-3 antibody
  • ACHRG antibody
  • Acrg antibody

Protein level used designations for CHRNG

acetylcholine receptor subunit gamma , acetylcholine receptor, muscle, gamma subunit , acetylcholine receptor, nicotinic, gamma (muscle) , cholinergic receptor, nicotinic, gamma polypeptide , acetylcholine receptor gamma-subunit , acetylcholine receptor gamma subunit , cholinergic receptor, nicotinic, gamma , acetylcholine receptor subunit gamma-like , AChR gamma subunit , chrng variant N1 , chrng variant N2 , nicotinic acetylcholine receptor gamma subunit

GENE ID SPECIES
1146 Homo sapiens
281689 Bos taurus
386669 Xenopus laevis
429151 Gallus gallus
470680 Pan troglodytes
713418 Macaca mulatta
100400765 Callithrix jacchus
100443951 Pongo abelii
25753 Rattus norvegicus
486163 Canis lupus familiaris
100125132 Xenopus (Silurana) tropicalis
100593613 Nomascus leucogenys
11449 Mus musculus
101102965 Ovis aries
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