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Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. Additionally we are shipping CHAD Antibodies (17) and CHAD Kits (6) and many more products for this protein.
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number of cells adhering via their beta(1) integrin receptor to collagen type II or chondroadherin was profoundly and rapidly enhanced by the addition of the heparin-binding peptide (show HP Proteins)
chondroadherin interaction with cells may be central for maintaining the adult chondrocyte phenotype and cartilage homeostasis.
Changes in CHAD abundance or structure could be associated with the pathologic changes occurring in the scoliotic IVD (show IVD Proteins).
Chondroadherin likely affects cartilage modulus by regulating collagen network.
The skeletal phenotype points at a role for chondroadherin in both bone and cartilage homeostasis, however, without leading to altered longitudinal growth.
Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in chondrocytes at all ages.
, cartilage leucine-rich protein
, chondroadherin proteoglycan
, 38 kDa bone protein